Apparatus and process using second derivative of oscillometric waveform for producing sphygmometric information
First Claim
1. An apparatus for producing information indicative of the physical condition of a living test subject comprising:
- means for applying a selectively changeable pressure to the test subject adjacent a blood vessel;
means for measuring a fluctuating quantity proportional to a sum, said sum comprising a time-dependent fluctuating component representative of the pulsatile pressure within the blood vessel, plus the selectively changeable pressure applied externally adjacent the blood vessel;
means for converting said quantity into a representation of a time derivative of at least the fluctuating component thereof, said time derivative being at least the second time derivative of said fluctuating component;
means for analyzing changes in said representation of said at least second time derivative induced by changing the applied pressure, said analyzing means including means for determining and representing whether or not said at least second time derivative at least attains a particular negative threshold value, and means responsive to a change in the state of said threshold attainment representation as a function of said applied pressure for producing an output corresponding substantially with the applied pressure which results in a respective said state-change and is to a close approximation equal to at least one of either the diastolic or the systolic pressures of the blood vessel of the living test subject as determined by the direction of said state-change as a function of the direction of applied pressure change.
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0 Petitions
Accused Products
Abstract
An improved method and apparatus for determining blood pressure in a system employing a variable pressure cuff and having means for sensing a quantity comprising the sum of applied cuff pressure and a component representative of pulsatile pressure in a blood vessel, a particular time derivative of at least the fluctuating component of the quantity is obtained and utilized for determining blood pressure. More specifically, the particular time derivative comprises the second (or greater) derivative and it is analyzed to determine at what applied pressure it first and last crosses a negative threshold value, those pressures then being indicated as diastolic and systolic pressure depending on whether applied pressure is increased or decreased. The threshold value may be dynamically determined.
63 Citations
15 Claims
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1. An apparatus for producing information indicative of the physical condition of a living test subject comprising:
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means for applying a selectively changeable pressure to the test subject adjacent a blood vessel; means for measuring a fluctuating quantity proportional to a sum, said sum comprising a time-dependent fluctuating component representative of the pulsatile pressure within the blood vessel, plus the selectively changeable pressure applied externally adjacent the blood vessel; means for converting said quantity into a representation of a time derivative of at least the fluctuating component thereof, said time derivative being at least the second time derivative of said fluctuating component; means for analyzing changes in said representation of said at least second time derivative induced by changing the applied pressure, said analyzing means including means for determining and representing whether or not said at least second time derivative at least attains a particular negative threshold value, and means responsive to a change in the state of said threshold attainment representation as a function of said applied pressure for producing an output corresponding substantially with the applied pressure which results in a respective said state-change and is to a close approximation equal to at least one of either the diastolic or the systolic pressures of the blood vessel of the living test subject as determined by the direction of said state-change as a function of the direction of applied pressure change. - View Dependent Claims (2, 3, 4, 5, 6)
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7. In an apparatus for producing information indicative of the physical condition of a living test subject, said apparatus including means for applying a selectively changeable pressure to the test subject adjacent a blood vessel and means for measuring a fluctuating quantity proportional to a sum, said sum comprising a time-dependent fluctuating component representative of the pulsatile pressure within the blood vessel, plus the selectively changeable pressure applied externally adjacent the blood vessel, the improvement comprising:
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means for converting said quantity into a representation of a time derivative of at least the fluctuating component thereof, said time derivative being at least the second time derivative of said fluctuating component; means for analyzing changes in said representation of said at least second time derivative induced by changing the applied pressure, said analyzing means including means for determining and representing whether or not said at least second time derivative at least attains a particular threshold value, said threshold value being a fraction of the maximum negative magnitude attained by said second time derivative representation across a continuous range of applied pressures which includes the diastolic-systolic pressures of the blood vessels, and means responsive to a change in the state of said threshold attainment representation as a function of said applied pressure for producing an output corresponding substantially with the applied pressure which results in a respective said state-change and is to a close approximation equal to either the diastolic or the systolic pressures of the blood vessel of the living test subject as determined by the direction of said state-change as a function of the direction of applied pressure change. - View Dependent Claims (8)
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9. A method for producing information indicative of the physical condition of a living test subject comprising:
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applying a selectively changeable pressure to the subject externally adjacent the blood vessel; measuring a quantity proportional to a sum, said sum comprising a time dependent fluctuating component representative of the pulsatile pressure within the blood vessel, plus the changeable pressure applied externally adjacent the blood vessel; converting said quantity into a representation of the second time derivative of at least the fluctuating component thereof; analyzing changes in said representation in said second time derivative induced by changing the applied pressure, said analyzing comprising the steps of determining and representing whether or not said second time derivative at least attains a particular negative threshold value and identifying a change in the state of said representation of threshold attainment in successive pulses as a function of the applied pressure; and producing from said identifying an output corresponding substantially with the applied pressure which results in a respective said state-change and is to a close approximation equal to at least one of either the diastolic or the systolic pressures of the blood vessel of the living test subject as determined by the direction of said state-change as a function of the direction of applied pressure change. - View Dependent Claims (10, 11, 12, 13)
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14. In a method for producing information indicative of the physical condition of a living test subject, including applying a selectively changeable pressure to the subject externally adjacent the blood vessel and measuring a quantity proportional to a sum, said sum comprising a time-dependent fluctuating component representative of the pulsatile pressure within the blood vessel, plus the changeable pressure applied externally adjacent the blood vessel, the improvement comprisng:
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converting said quantity into a representation of the second time derivative of at least the fluctuating component thereof; analyzing changes in said representation in said second time derivative induced by changing the applied pressure, said analyzing comprising the steps of determining and representing whether or not said second time derivative at least attains a particular threshold value, said threshold value being a fraction of the maximum negative magnitude attained by said second time derivative representation across a continuous range of applied pressures which includes the diastolic-systolic pressures of the blood vessls, and identifying a change in the state of said representation of threshold attainment in successive pulses as a function of the applied pressure; and producing from said identifying an output corresponding substantially with the applied pressure which results in a respective said state-change and is to a close approximation equal to either the diastolic or the systolic pressures of the blood vessel of the living test subject as determined by the direction of said state-change as a function of the direction of applied pressure change. - View Dependent Claims (15)
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Specification