Fluid self-sealing bioelectrode

• US 4,166,457 A
• Filed: 11/14/1977
• Issued: 09/04/1979
• Est. Priority Date: 08/16/1976
• Status: Expired due to Term

• Current Assignee: University of Utah Research Foundation (State of Utah)
• Original Assignee: University of Utah Research Foundation (State of Utah)
• Inventors: Jacobsen, Stephen C., Knutti, David F., Stephen, Robert L., Johnson, Richard T., Luntz, Richard D., Mandleco, Carl F.
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US05/851,082
• Time in Patent Office: 659 Days
• Field of Search: 128/2.06 E, 128/2.1 E, 128/404, 128/410, 128/411, 128/416-418, 128/DIG. 4
• US Class Current: 600/397
• CPC Class Codes: A61B 2562/0217 Electrolyte containing
• CPC Class Codes: A61B 5/324 Means for providing electrolytes, e.g. syringes
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428

Abstract

A dry-state bioelectrode having a self-sealing receptacle for receiving electrolyte and/or medicament fluid contents. The receptacle is attached at its opening to a sheet-like flexible base member having an opening in common with the receptacle opening, the bottom of the base member being adapted for fixation at a skin surface. A portion of the skin surface is exposed to the fluid contents of the receptacle through the common opening. An injection site communicates through the wall of the receptacle and provides controlled access for filling. Upon completion of filling, the receptacle self seals, retaining the fluid contents therein for application of iontophoresis treatment or other procedures requiring use of a potential gradient. An electrode plate is supported at an interior surface of the receptacle for supplying the desired electric potential.

Claims

1. A self-sealing bioelectrode for use with electrode fluids including:

(a) a sheet-like base member having a base opening therethrough, and adapted at a bottom surface thereof for conforming contact at a skin surface;

(b) a receptacle having an opening which is attached at said base member to define a fluid channel through said base opening to the interior of said receptacle;

(c) an injection channel means communicating between the exterior and interior of said receptacle for filling said receptacle with fluid when affixed at said skin surface, said channel means having restricted access means for passing said fluid into said receptacle while precluding subsequent introduction of other fluids therethrough;

(d) a conductive electrode plate disposed within said receptacle interior at such location so as to be remote from said base opening when said electrode is filled with fluid; and

(e) means for coupling said electrode plate to an electric circuit.

2. An electrode as defined in claim 1, wherein said receptacle is constructed of deformable material which adapts said receptacle to be flattened against said base member causing the receptacle to be substantially void of air when in a dry-state, but expandable when filled with fluid after being affixed to said skin surface.

3. An electrode as defined in claim 1, further comprising a reservoir means integrally attached to and having opening means communicating at said injection channel means.

4. An electrode as defined in claim 3, wherein said reservoir means comprises a prefilled bag of electrode fluid having a weak seal as opening means thereof and being operable to break upon squeezing to facilitate discharge of bag contents into the injection channel means.

5. An electrode as defined in claim 3 wherein said restricted access means comprises:

a. breakaway connection means between the reservoir means and injection channel means which is adapted to break upon bending or twisting to form an opening from said reservoir means to a tube flow channel,

b. radially protruding rib structure projecting along a length of said breakaway connection means and being attached at the reservoir means,

c. an enclosing elastic tube attached at said injection channel means and stretched around said breakaway connection means, said tube being partially extended along an intermediate length thereof away from an exterior surface of said channel means by said rib structure to thereby form said tube flow channel between said exterior surface and said elastic tube, and

d. said opening means communicating from said tube flow channel to said injection channel means.

6. An electrode as defined in claim 1, further comprising a wicking member disposed across said base opening proximate to said bottom surface.

7. An electrode as defined in claim 1, wherein said base member is made of flexible material adaptable for emplacement over sharply contoured skin surfaces.

8. An electrode as defined in claim 1, further comprising an absorbent shield disposed interior of said receptacle between said electrode plate and said base opening and having sufficient size for precluding substantial physical contact between contacting interior surfaces of said receptacle and between said electrode plate and said skin surface.

9. An electrode as defined in claim 1, wherein said injection channel means includes a flow channel communicating between said receptacle interior and an external location.

10. An electrode as defined in claim 9, wherein said restricted access means comprises a self-sealing plug located within said channel and impervious to fluids except as they may be delivered through said plug by an inserted syringe means.

11. An electrode as defined in claim 9, wherein said channel is disposed along the top surface of said base member providing a direction of electrolyte injection substantially parallel to said top surface and away from said skin surface.

12. An electrode as defined in claim 1, further comprising means for two-stage injection of electrolyte, said first stage comprising means for blocking fluid flow from an inserted tip of an electrolyte containing syringe means to facilitate temporary storage in ready-to-charge condition, and a second stage comprising means requiring further movement of said syringe means to enable communication of electrolyte through said tip to said receptacle interior.

13. An electrode as defined in claim 1, wherein said electrode plate has a periphery and surface substantially similar in contour to said base opening for improving uniform electric field at said opening during operation.

14. An electrode as defined in claim 1, wherein said electrode plate coupling means comprises an exterior conductive plate mounted opposite and electrically coupled to said interior plate with a wall section of the receptacle compressed therebetween to seal off fluid flow between said plates, said exterior plate having means for coupling to external electrical circuitry.

15. An electrode as defined in claim 14, wherein said electrical coupling between said interior and exterior plates comprises a spot weld connection.

16. An electrode as defined in claim 1, further comprising a removable SYRETTE coupled to said injection channel means for charging said electrode, said SYRETTE including a closed chamber having a pumping means and a cannula means providing a fluid path between said chamber and an exterior point from said SYRETTE, said cannula means being adapted for mating with a section of said injection channel means to form a continuous channel connecting said chamber with said receptacle interior.