Calculated parameter generation in a hematology parameter measurement apparatus

• US 4,167,038 A
• Filed: 10/17/1977
• Issued: 09/04/1979
• Est. Priority Date: 10/17/1977
• Status: Expired due to Term

• Current Assignee: The First National Bank of Boston (Bank of America Corp.)
• Original Assignee: Boehringer Mannheim Diagnostics Corp. (Roche Holding AG)
• Inventors: Hennessy, James W.
• Primary Examiner(s): Smith, Jerry
• Application Number:
  US05/842,508
• Time in Patent Office: 687 Days
• Field of Search: 364/416, 364/555, 128/2 G, 235/92 PC, 235/92 PL, 324/71 CP, 356/39
• US Class Current: 600/368
• CPC Class Codes: G01N 15/132 Circuits

Abstract

In a hematology parameter measuring apparatus, signals indicative of measured parameters are obtained and loaded into first digital registers. Calculated parameter values are generated through use of the values stored in the digital registers. A first parameter value is circulated from a register into a digital divider through a digital data line to set a divisor in the divider. A control circuit circulates a value from another register to the divider for utilization as a signal indicative of a dividend. The output of the divider is coupled to a result register to store a value indicative of the calculated parameter. In this manner, calculated parameter values are obtained, and the first registers retain values indicative of the measured parameter values. The control means may selectively couple signals to a display from any of the registers or to a printing unit.

Claims

1. In a hematology parameter measuring apparatus for producing outputs indicative of measured values including transducer means for producing signals indicative of parameter values and register means for storing indications of measured values, the improvement of means for producing calculated parameter values comprising:

calculation means for calculating a calculated value as a function of measured values supplied thereto and comprising a digital divider having a dividend register and a divisor register, control means for commanding generation of calculated parameter values and means for supplying preselected measured values from said register means in a preselected sequence to said calcuation means in response to an input from said control means, wherein said register means comprises parameter registers, and said means for supplying preselected measured value comprises means for circulating a value from one of said parameter registers to one of said registers in said digital divider and means for applying a source of clock pulses for incrementing said parameter register by a number of counts to return to its original setting, means for sensing the overflow of said parameter register, and means for providing to each said register in said digital divider a multiple of the number of counts provided to the parameter register after overflow until the provision of the number of counts to the parameter register is completed, whereby said calculation means provides an output indicative of a calculated value.

2. Apparatus according to claim 1 wherein said means for circulating a value from one of said parameter registers to said divisor registers comprises means for providing to said divisor register a number of counts equal to counts occurring after overflow until the provision of the number of counts to the parameter register is completed.

3. Apparatus according to claim 2 wherein said means for circulating a value from one of said parameter registers to said dividend register comprises means for providing to said dividend register a multiple of the number of counts provided to the parameter register after overflow until the provision of the number of counts provided to the parameter register is completed which multiple is equal to a scaling factor.

4. Apparatus according to claim 1 wherein said parameter registers comprise a white blood cell count register, red blood cell count register, hemoglobin register, and hematocrit register, and wherein said means for supplying preselected measured values comprises means for accessing a value from each parameter register indicative of the parameter by which the parameter register is named.

5. Apparatus according to claim 4 wherein said means for preselected measured values comprises means for circulating a value from the red blood cell count register to the divisor register and for circulating a value dependent upon the value in the hematocrit register to dividend register whereby said digital divider provides an output indicative of mean corpuscular volume, means for circulating a value indicative of the value in the red blood cell count register to the divisor register and circulating a value based on the value in the hemoglobin register to said dividend register, whereby said digital divider provides an output indicative of mean corpuscular hemoglobin, and means for circulating a value from said hematocrit register to said divisor register and for circulating a value based on the value in the hemoglobin register to the dividend register, whereby said digital divider provides an output indicative of mean corpuscular hemoglobin concentration.

6. In a method for producing parameter values in a hematology parameter measuring apparatus comprising producing signals indicative of measured values and storing said signals in register means, the improvement of:

providing calculation means comprising a digital divider having a dividend register and a divisor register for producing calculated values as a function of measured values supplied thereto, and providing in response to a command preselected ones of said measured values in a predetermined sequence to said calculation means comprising providing a first measured value from a first register to the dividend register and providing a second measured value from a second register to said divisor register, the step of providing a value from a register to said calculating means comprising providing a number of counts to said register to return said register to its original setting, sensing reset of said register and providing a multiple of the number of counts produced after reset to said calculation means, whereby a value indicative of said calculated value from said calculation means is provided.

7. The method according to claim 6 further comprising the step of providing a result register and providing the signal indicative of each calculated value to a location in a result register.