Device for rheoplethysmography by occlusion

• US 4,169,463 A
• Filed: 06/06/1977
• Issued: 10/02/1979
• Est. Priority Date: 06/16/1976
• Status: Expired due to Term

• Current Assignee: Commissariat a L'Energie Atomique (French Alternative Energies and Atomic Energy Commission)
• Original Assignee: Commissariat a L'Energie Atomique (French Alternative Energies and Atomic Energy Commission)
• Inventors: Piquard, Jean-Francois
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US05/803,776
• Time in Patent Office: 848 Days
• Field of Search: 128/25, 128/2.05 A, 128/2.05 P, 128/2.05 V, 128/2.1 Z
• US Class Current: 600/506
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295

Abstract

The device for studying vascular behavior particularly in a lower limb of a patient comprises pressure applying means for causing occlusion of the limb under study, means for controlling the characteristics of progressive variation in the pressure applied by the pressure-applying means as a function of time during occlusion of the limb under study, a plethysmograph for delivering signals which are representative of an electrical impedance related to the limb under study and of variations in such electrical impedance, and means for determining, from coefficients of standardization which are characteristic of the healthy vascular operation of a normal limb of the same type as the limb under study and from the signals, indices which are representative of the vascular behavior of the limb under study.

Claims

1. A device for rheoplethysmography by occlusion adapted in particular to the study of vascular behavior of a lower limb of a patient comprising pressure-applying means for causing occlusion of a lower limb under study, means for controlling the characteristics of progressive variation in the pressure applied by the pressure-applying means as a function of time during occlusion of the limb under study, a plethysmograph for delivering signals which are representative of an electrical impedance related to said limb under study and of the variations in said electrical impedance, of a normal limb of the same type as the limb under study, and means for determining, from coefficients of standardization which are characteristic of the healthy vascular operation of a normal limb of the same type as the limb under study and said signals, indices which are representative of the vascular behavior of said limb under study, said pressure-applying means including a control loop having a amplifier for establishing a comparison between a predetermined reference value and the value of the pressure within the collar, a transducer for measuring said collar pressure, a circuit means for controlling the inflation of the collar, and a pump which inflates said collar.

2. A device according to claim 1, including means for the visual display of the standardized values of said indices.

3. A device according to claim 2, wherein the visual display means includes a calibrated galvanometer provided in the case of each index with references corresponding to predetermined pathological thresholds defining means for comparison with the predetermined thresholds.

4. A device according to claim 2, wherein the visual display means includes an X-Y recorder provided in the case of each index with references corresponding to predetermined pathological thresholds defining means for comparison with the predetermined thresholds.

5. A device according to claim 1 including means for comparing said indices with predetermined discrimination thresholds.

6. A device according to claim 1 wherein the pressure-applying means for causing occlusion of the limb includes a pneumatically inflated collar which surrounds said limb, and a pneumatic inflating device for inflating said collar.

7. A device according to claim 1, including means for releasing the occlusion in the form of a solenoid-actuated exhaust valve connected to said collar.

8. A device according to claim 1, wherein said measurement indices represent:

an index of rate of filling of the vascular territory during occlusion, characterized by an initial slope P_r of a curve which gives the variation in measured limb impedance as a function of time,

an index of extensibility at the time of limb filling, characterized by the amplitude of filling or the venous capacity A_r as a function of the maximum value of the time-dependent variation in limb impedance,

an index of rate of evacuation at release of the occlusion, characterized by a slope at a point of origin P_v of a curve which represents the variation in limb impedance as a function of time,

an evacuation index characterized by the amplitude of evacuation or the venous contraction A_v as a function of the maximum value of the time-dependent variation in limb impedance,

an evacuation time constant C_v

a coefficient of elasticity of the veins of the limb under study as a function of the variation in limb impedance in accordance with the applied pressure,

a venous pressure defining a threshold from which a variation in limb impedance takes place as a function of the applied pressure.

9. A device according to claim 1, wherein the means for determining the indices from the coefficients of standardization and from the signals include an analog circuit and means for visually displaying and recording of curves of said signals.

10. A device according to claim 1 including a sequencer for programming the characteristics of the pressure applied by the pressure-applying means for programming the conditions of recording of the signals and for programming the measurement of the particular indices desired.

11. A device according to claim 10, wherein the pressure applied is represented by a step function, a ramp function, a ramp-step function, or the like.

12. A device according to claim 10 including a logical operator for assisting diagnosis the said operator comparing measured indices with predetermines values.

13. A device according to claim 1, wherein the plethysmograph includes a four-pole impedance plethysmograph.

14. A device according to claim 1, wherein the plethysmograph includes an extensometer gage.