Heat exchanger for blood

• US 4,177,816 A
• Filed: 03/27/1978
• Issued: 12/11/1979
• Est. Priority Date: 03/27/1978
• Status: Expired due to Term

• Current Assignee: Avecor Incorporated (Medtronic Plc)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Torgeson, William L.
• Primary Examiner(s): Trapp, Lawrence W.
• Application Number:
  US05/890,077
• Time in Patent Office: 624 Days
• Field of Search: 128/399, 128/400, 128/401, 128/402, 165/172, 165/177, 165/46, 165/158, 23/258.5
• US Class Current: 607/106
• CPC Class Codes: A61F 7/00 Heating or cooling appliances for medical or therapeutic treatment of the human body heating or cooling means in connection with bedsteads or mattresses A47C21/00 ; massage, therapeutic baths A61H; hyperthermia using electric or magnetic fields or ultrasound A61N; electric heating elements H05B
• CPC Class Codes: A61M 2205/366 by liquid heat exchangers
• CPC Class Codes: A61M 5/44 having means for cooling or heating the devices or media
• CPC Class Codes: F28D 2021/005 for medical applications
• CPC Class Codes: F28D 7/16 the conduits being arranged in parallel spaced relation F28D7/0008 - F28D7/0058 take precedence; F28D7/02 - F28D7/10 take precedence
• CPC Class Codes: F28F 13/06 by affecting the pattern of flow of the heat-exchange media F28F13/003 takes precedence; static flow control means in header boxes F28F9/026

Abstract

A disposable, tube-and-shell heat exchanger for controlling the temperature of blood. The tube portion includes a plurality of parallel tubes having serpentine inserts therein in heat-exchange contact with smooth inner walls of the tubes. The tubes are of sufficient number, length and flow area to permit gentle laminar blood flow at 37° C. of up to five liters per minute.

Claims

1. A disposable heat exchanger for controlling the temperature of blood, comprising a plurality of generally parallel tubes having smooth inner walls, inlet and outlet means for supplying blood to and for collecting blood from the tubes, a jacket about the tubes having inlet and outlet means enabling the flow of a heat exchange medium through the jacket and in heat exchange proximity with the tubes, the tubes being characterized by including elongated inserts therein, each insert having periodic reverse bends providing the insert with a serpentine configuration, outer surfaces of the bends being in heat-exchange contact with inner walls of the tubes, the tubes with inserts being of sufficient number, length and flow area to enable gentle, laminar blood flow through the tubes at 37°

C. at a rate of up to about 5 liters per minute.

2. The heat exchanger of claim 1 wherein the inserts are ribbon-like in configuration and have a generally rectangular cross-section with rounded edges, the maximum cross-sectional width of the inserts being not greater than about 90 percent of the inner diameter of the tubes.

3. The heat exchanger of claim 1 wherein the inserts are generally circular in cross-section and have a diameter not greater than about 40 percent of the inner diameter of the tubes.

4. The heat exchanger of claim 1 including a thin, continuous, biologically-acceptable coating disposed upon all blood-confronting surfaces of the tubes and inserts.

5. The heat exchanger of claim 1 in which the total priming volume of the tubes with inserts is not greater than about 125 milliliters.

6. The heat exchanger of claim 5 so constructed and arranged as to provide a flow of blood, under a pressure drop of 85 mm of mercury and at a temperature of 37°

C., at a rate of not less than about 5 liters per minute and wherein the latter blood flow is characterized by a Reynolds number of not greater than about 400.

7. The heat exchanger of claim 1 in which the number of reverse insert bends in a length of tubing equal to ten times the tubing inner diameter, is from about 2 to about 8.

8. The blood heat exchanger of claim 1 in which the tubes and inserts are of metal and are in metal-to-metal contact with one another, the interior of each tube and the insert therewithin having a continuous, thin, biologically-acceptable coating thereon.

9. A disposable heat exchanger for controlling the temperature of blood, the heat exchanger comprising a plurality of metal tubes having smooth interior walls and circular cross-sections, inlet and outlet means for supplying blood to and for collecting blood from the tubes, heat-exchange means for applying a heat exchange medium to exterior surfaces of the tubes, the tubes having elongated metal inserts therein, each insert having periodic reverse bends along its length providing the insert with a serpentine configuration, exterior surfaces of the inserts at such bends lying in metal-to-metal contact with interior surfaces of the tubes and being retained in the tubes by friction between the contacting surfaces of the tubes and inserts, the interiors of the tubes and surfaces of the associated inserts having a continuous, thin, biologically-acceptable coating thereon, the tubes with inserts being sufficient in number, length and flow area to provide, at a pressure drop across the tubes of not greater than about 85 mm of mercury and at a blood temperature of about 37°

C. a laminar flow of blood characterized by a Reynolds number of not greater than about 400 and a blood flow rate of not less than about 5 liters per minute.

10. The heat exchanger of claim 9 in which the total priming volume of the tubes with inserts is not greater than about 125 milliliters.

11. The heat exchanger of claim 10 in which the heat exchange means comprises a jacket formed about the tubes and having inlet and outlet means permitting counter current flow of a heat exchange medium about the tubes, the heat exchanger having a heat exchange effectiveness factor at a blood flow rate of 2 liters per minute of not less than about 0.5, the effectiveness factor being defined as ##EQU2##

12. The heat exchanger of claim 10 in which the inserts are of sufficient size as to reduce the area of the tubes available for blood flow by about 5 to about 25 percent.