Device for delivering drug to biological environment
First Claim
1. A drug delivery device comprising:
- (a) a drug;
(b) a housing having a shape-retaining wall defining an internal space, said housing having at least one opening connecting the space with the exterior of the device;
(c) a container in the housing, said container having a collapsible wall surrounding a reservoir for storing the drug and a passageway for delivering drug from the container to the exterior of the device; and
,(d) a laminate in the housing surrounding the container comprising a lamina of an absorbent material and a lamina of a swellable hydrophilic cross-linked polymer, said laminate capable of imbibing fluid into the housing thereby causing the laminate to expand and exert pressure on the container which collapses said container and concomitantly pumps drug through the passageway from the device at a controlled rate over a prolonged period of time.
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Accused Products
Abstract
A self-powered device for delivering drug is disclosed. The device comprises (1) a substantially rigid housing, (2) a collapsible container storing a drug and having a passageway for delivering the drug in the housing, and (3) an expandable laminate positioned between the housing and the container. The laminate comprises (a) a lamina formed of an absorbent material laminated to (b) a lamina placed adjacent to the container and formed of a swellable hydrophilic polymer. In operation, when the device is in a biological environment, fluid from the environment is imbibed by the laminate into the housing causing the laminate to expand and exert pressure on the container, thereby collapsing the container and concomitantly pumping drug through the passageway from the device at a correspondingly controlled rate over a prolonged period of time.
25 Citations
8 Claims
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1. A drug delivery device comprising:
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(a) a drug; (b) a housing having a shape-retaining wall defining an internal space, said housing having at least one opening connecting the space with the exterior of the device; (c) a container in the housing, said container having a collapsible wall surrounding a reservoir for storing the drug and a passageway for delivering drug from the container to the exterior of the device; and
,(d) a laminate in the housing surrounding the container comprising a lamina of an absorbent material and a lamina of a swellable hydrophilic cross-linked polymer, said laminate capable of imbibing fluid into the housing thereby causing the laminate to expand and exert pressure on the container which collapses said container and concomitantly pumps drug through the passageway from the device at a controlled rate over a prolonged period of time. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification