Device and method for treating and healing a newly created bone void

• US 4,186,448 A
• Filed: 11/21/1977
• Issued: 02/05/1980
• Est. Priority Date: 04/16/1976
• Status: Expired due to Term

• Current Assignee: Osmed Incorporated
• Original Assignee: John H. Brekke
• Inventors: Brekke, John H.
• Primary Examiner(s): Frinks, Ronald L.
• Application Number:
  US05/853,417
• Time in Patent Office: 806 Days
• Field of Search: 3/1, 3/1.9, 128/92 R, 128/92 B, 128/92 BC, 128/92 G, 128/334 R, 128/335.5, 128/325, 128/296
• US Class Current: 128/898
• CPC Class Codes: A61B 17/58 for osteosynthesis, e.g. bone plates, screws , setting implements or the like A61B17/14, A61B17/16 take precedence
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/2875 Skull or cranium A61F2/2803 and A61F2/3099 take precedence
• CPC Class Codes: A61F 2002/2878 for orbital repair
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61L 2300/252 Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
• CPC Class Codes: A61L 2300/412 Tissue-regenerating or healing or proliferative agents
• CPC Class Codes: A61L 2300/418 Agents promoting blood coagulation, blood-clotting agents, embolising agents
• CPC Class Codes: A61L 2430/02 for reconstruction of bones; weight-bearing implants
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: C08L 67/00 Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain of polyester-amides C08L77/12; of polyester-imides C08L79/08; Compositions of derivatives of such polymers

Abstract

Device and method for treating a newly created bone void or soft tissue deficiency including a one piece moldable body having a form sufficient to cover a bone void and made of a biodegradable material. The body includes enclosed interconnected randomly positioned, randomly shaped and randomly sized voids extending throughout the mass of the body member with each void communicating with the others and communicating with substantially the entire exterior of the body to which blood is attracted by capillary action from arteries leading to the bone void for saturation of the body with blood for the development of blood capillaries whereby the bone void is healed as the body member biodegrades.

Claims

1. The method of treating and healing a newly created bone void consisting in forming a one piece body of moldable biodegradable material having enclosed interconnected randomly positioned, randomly sized and randomly shaped voids therein and throughout, each void communicating with the others and communicating with substantially the entire exterior of the body and through which blood is attracted by capillary action to saturate the body with blood for blood vessel development throughout the body and the body of a size adapted to substantially fill the void said voids occupying about 90% of the volume of the body and said body having a wetting agent incorporated therewith, filling the void with the body, then allowing the blood saturated body to remain in the void whereby blood vessels are produced throughout the body and the bone void is healed as the body is biodegraded.

2. The method of claim 1 in which the biodegradable material is polylactic acid polymer.

3. The method of treating and healing tissue deficiencies consisting in forming a body member of a biodegradable material having enclosed interconnected randomly positioned, sized and shaped voids communicating substantially with each other and substantially with the entire exterior of the body, said voids occupying about 90% of the volume of the body and said body having a wetting agent incorporated therewith, then applying the body member to the tissue deficiency, then allowing the body member to remain whereby the tissue deficiency is healed and the body member biodegraded.

4. A device for treating and healing a newly created bone void comprising:

(a) a one piece body member formed of a biodegradable material,

(b) said body member having a form sufficient to fill and cover a bone void, and

(c) having enclosed interconnected randomly positioned and randomly sized and shaped voids therein each void connecting with the others and communicating with the exterior of the body through which voids blood is attracted by capillary action for saturation of the body with blood said voids occupying about 90% of the volume of the body and said body having a wetting agent incorporated therewith, whereby a bone void filled and covered by the body member is healed as the body member biodegrades.

5. The device of claim 4 in which the biodegradable material is polylactic acid polymer.

6. The device of claim 4 in which said body member material has a therapeutic agent incorporated in said material to assist healing.

7. The method of treating and healing a tissue deficiency in the orbital floor consisting in forming a sheet member of a biodegradable material including a first layer having a solid smooth outer surface which is integral with a second opposed layer having enclosed randomly positioned and randomly sized and shaped interconnected voids therein and communicating with the exterior thereof through which blood is attracted by capillary action to saturate the second opposed layer with blood, said voids occupying about 90% of the second layer and said sheet member having a wetting agent incorporated therewith, then applying the sheet member to the tissue deficiency, then allowing the sheet member to remain whereby the tissue deficiency is healed and the sheet member biodegraded.

8. A device for treating a bone fracture comprising:

(a) a one piece body member formed of a biodegradable material,

(b) a first portion of said body member being solid in formation and surrounding in one plane

(c) a further portion of said body member having enclosed interconnected randomly sized, randomly poritioned and randomly shaped voids therein;

each void connecting with the others and communicating with the exterior of the body through which voids blood is attracted by capillary action for saturation of the body with blood, said voids occupying about 90% of the volume of the further portion and said body member having a wetting agent incorporated therewith, said further body portion biodegrading first and followed by the biodegrading of the first portion. a product being pierced; and

means for locking said stripper carriage in position with said stripper plate resting upon a product while said knives are being withdrawn from the product.