Method of storing a biological reference control standard and biological reference control standard obtained thereby
First Claim
1. An improved method of storing a blood serum reference composition for subsequent use in analysis of biologically similar unknowns, said composition comprising in its non-biological component from about 40 to about 85 weight percent water, from about 15 to about 60 weight percent of at least one alkylene polyol having from 2 to 5 carbon atoms, the remainder being chiefly at least one labile natural biological material selected from a group consisting of blood serum, enzyme, metabolites, electrolytes, and hormones, wherein the improvement comprises lowering the temperature of said composition to below the freezing point thereof and storing said composition in a frozen state.
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Abstract
An improved method of storing and shipping a blood serum reference composition comprising in its non-biological component from about 40 to about 85 weight percent water, from about 15 to about 60 weight percent of at least one alkylene polyol having from 2-5 carbon atoms, the remainder being chiefly at least one natural biological material selected from a group consisting of blood serum, enzyme, metabolites, electrolytes, and hormones. The improvement comprises storing and/or shipping the composition at a temperature below the freezing point thereof.
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10 Claims
- 1. An improved method of storing a blood serum reference composition for subsequent use in analysis of biologically similar unknowns, said composition comprising in its non-biological component from about 40 to about 85 weight percent water, from about 15 to about 60 weight percent of at least one alkylene polyol having from 2 to 5 carbon atoms, the remainder being chiefly at least one labile natural biological material selected from a group consisting of blood serum, enzyme, metabolites, electrolytes, and hormones, wherein the improvement comprises lowering the temperature of said composition to below the freezing point thereof and storing said composition in a frozen state.
- 6. A frozen blood serum reference composition for use in analysis of biologically similar unknowns upon thawing, said composition comprising in its non-biological component from about 40 to about 85 weight percent water, from about 15 to about 60 weight percent of at least one alkylene polyol having from 2 to 5 carbon atoms, the remainder being chiefly at least one labile natural biological material selected from a group consisting of blood serum, enzymes, metabolites, electrolytes, and hormones.
Specification