Apparatus for conducting fluids in a dialysis system

• US 4,191,646 A
• Filed: 10/13/1977
• Issued: 03/04/1980
• Est. Priority Date: 10/14/1976
• Status: Expired due to Term

• Current Assignee: Gambro Lundia AB (Baxter International Inc.)
• Original Assignee: Gambro AB (Baxter International Inc.)
• Inventors: Larsson, Lars-Ake L., Traven, Lars J. C.
• Primary Examiner(s): Wyse, Thomas G.
• Assistant Examiner(s): Sadowski, David R.
• Application Number:
  US05/841,896
• Time in Patent Office: 873 Days
• Field of Search: 210/85, 210/90, 210/137, 210/143, 210/149, 210/181, 210/321 B, 210/103, 210/321 HT, 137/517, 165/32, 165/40, 165/46, 165/96
• US Class Current: 210/103
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: F16K 7/02 with tubular diaphragm
• CPC Class Codes: Y10S 210/929 Hemoultrafiltrate volume measurement or control processes

Abstract

Fluid conducting apparatus is disclosed for a dialysis system having a dialyzer, a source of dialysis fluid for the dialyzer, a heating chamber for heating dialysis fluid before introduction into the dialyzer, and pump means for pumping heated dialysis fluid from the heating chamber to and through the dialyzer. The fluid conducting apparatus includes first and second fluid conducting means. The first fluid conducting means is adapted to be connected to the source of dialysis fluid and to the heating chamber for introducing dialysis fluid into the heating chamber, and the second fluid conducting means is adapted to be connected to the heating chamber, the dialyzer and the pump means for conducting the fluid from the heating chamber to and through the dialyzer. The apparatus also includes shut-off means adapted to terminate the flow of heated dialysis fluid from the heating chamber to the dialyzer when the rate of flow of fluid out of the chamber exceeds the rate of flow of fluid into the chamber. In this way, the heating chamber will not be emptied of dialysis fluid.

Claims

1. Apparatus for conducting fluids in a dialysis system having a dialyzer, a source of dialysis fluid for the dialyzer, heating means for heating dialysis fluid before introduction into the dialyzer, and pump means for pumping heated dialysis fluid to and through the dialyzer, said fluid conducting apparatus comprising:

a heating chamber for cooperation with said heating means to heat fluid introduced into said heating chamber, said heating chamber comprising a collapsible member having an inlet for introducing dialysis fluid into said collapsible member and an outlet for withdrawing fluid from said collapsible member;

first fluid conducting means for connection to the source of dialysis fluid and to said inlet of said heating chamber collapsible member for delivering dialysis fluid from the source of dialysis fluid to said heating chamber collapsible member;

second fluid conducting means for connection to said outlet of said heating chamber collapsible member, the dialyzer, and the pump means for conducting fluid from said heating chamber collapsible member to and through the dialyzer; and

shut-off means associated with said second fluid conducting means for terminating the flow of fluid from said heating chamber collapsible member to the dialyzer to prevent the emptying of fluid from said heating chamber collapsible member, said shut-off means comprising first and second flexible wall portions of said heating chamber collapsible member, said first and second flexible wall portions being juxtaposed to one another and arranged to be free to more between an open, separated position and a closed, abutting position, and said outlet of said heating chamber collapsible member being positioned in said first flexible wall portion so that when the amount of fluid being withdrawn from said heating chamber collapsible member exceeds the amount of fluid being introduced into said heating chamber collapsible member and the amount of fluid in said heating chamber collapsible member falls below a predetermined value, said first and second flexible wall portions are caused to move towards said closed, abutting position whereby said second flexible wall portion closes said outlet in said first flexible wall portion.

2. The apparatus of claim 1 wherein said flexible wall portions are planar and parallel to one another.

3. The apparatus of claim 1 wherein said first fluid conducting means, said second fluid conducting means and said shut-off means are disposable.

4. An improved dialysis system for treating a first fluid with dialysis fluid, the system comprising:

a dialyzer in which the treatment occurs;

a source of dialysis fluid for said dialyzer;

a heating chamber having heating means for heating the dialysis fluid before being conducted to said dialyzer, said heating chamber comprising a collapsible member having an inlet for introducing dialysis fluid into said collapsible member and an outlet for withdrawing fluid from said collapsible member;

first fluid conducting means for delivering dialysis fluid from said source of dialysis fluid to said heating chamber collapsible member;

second fluid conducting means for conducting fluid from said heating chamber collapsible member to and through said dialyzer;

first pump means in said second fluid conducting means for pumping through said second fluid conducting means dialysis fluid from said heating chamber collapsible member to and through said dialyzer; and

shut-off means associated with said second fluid conducting means for terminating the flow of fluid from said heating chamber collapsible member to said dialyzer to prevent emptying of fluid from said heating chamber collapssible member, said shut-off means comprising first and second flexible wall portions of said heating chamber collapsible member, said first and second flexible wall portions being juxtaposed to one another and arranged to be free to move between an open, separated position and a closed, abutting position, and said outlet of said heating chamber collapsible member being positioned in said first flexible wall portion so that when the amount of fluid being withdrawn from said heating chamber collapsible member exceeds the amount of fluid being introduced into said heating chamber collapsible member and the amount of fluid in said heating chamber collapsible member falls below a predetermined value, said first and second flexible wall portions are caused to move towards said closed, abutting position whereby said second flexible wall portion closes said outlet in said first flexible wall portion.

5. The dialysis system of claim 4 further including second pump means for pumping dialysis fluid to said heating chamber collapsible member through said first fluid conducting means.

6. The dialysis system of claim 5 further including pressure stabilizing means responsive to the pressure in said first fluid conducting means for controlling said second pump means to maintain a substantially constant pressure in said first fluid conducting means.

7. The dialysis system of claim 6 wherein said pressure stabilizing means comprises pressure measuring means for measuring the pressure in said first fluid conducting means and control means for controlling said second pump means, said control means being responsive to the pressure measured by said pressure measuring means to control said second pump means so as to maintain the pressure measured by said pressure measuring means substantially constant.

8. The dialysis system of claim 7 further including means for preventing dialysis fluid in said first fluid conducting means from coming into contact with said pressure measuring means.

9. The dialysis system of claim 4 wherein said flexible wall portions are planar and parallel to one another.

10. The dialysis system of claim 4 further including pressure stabilizing means responsive to the pressure in said second fluid conducting means for controlling said first pump means to maintain a substantially constant pressure in said second fluid conducting means when said shut-off means terminates the flow of fluid from said heating chamber collapsible member.

11. The dialysis system of claim 10 wherein said pressure stabilizing means comprises pressure measuring means for measuring the pressure in said second fluid conducting means, and control means for controlling said first pump means, said control means being responsive to the pressure measured by said pressure measuring means to control said first pump means so as to maintain the pressure measured by said pressure measuring means substantially constant.

12. The dialysis system of claim 11 further including means for preventing dialysis fluid in said second fluid conducting means from coming into contact with said pressure measuring means.

13. The dialysis system of claim 4 wherein said first fluid conducting means, said second fluid conducting means and said shut-off means are disposable.

14. The dialysis system of claim 13 wherein the source of dialysis fluid comprises a receptacle containing dialysis fluid.

15. The dialysis system of claim 14 wherein said second fluid conducting means communicates with said receptacle downstream of said dialyzer, and wherein said receptacle further includes regeneration means for cleaning dialysis fluid that has been conducted through said dialyzer.

16. The dialysis system of claim 14 wherein said second fluid conducting means communicates with said receptacle downstream of said dialyzer, and wherein said receptacle includes means for collecting ultrafiltrate from said dialyzer during ultrafiltration.

17. The dialysis system of claim 16 wherein said means for collecting ultrafiltrate includes a spillway for said receptacle positioned at substantially the same elevation as the elevation of dialysis fluid in said receptacle prior to operation of said dialysis system, and a container for collecting run-off from said spillway, so that any ultrafiltrate conducted to said receptacle will run off said spillway and into said container.

18. The apparatus of claim 14 wherein said receptacle includes means for emptying said receptacle of dialysis fluid, and wherein said receptacle is disposable.

19. The apparatus of claim 4 wherein said heating chamber collapsible member includes temperature measuring means for measuring the temperature of dialysis fluid in said heating chamber collapsible member and control means responsive to the temperature measured by said temperature measuring means for controlling said heating means in order to maintain a desired temperature of dialysis fluid in said heating chamber collapsible member.