System for measurement of oxygen uptake and respiratory quotient

• US 4,197,857 A
• Filed: 04/06/1978
• Issued: 04/15/1980
• Est. Priority Date: 04/06/1978
• Status: Expired due to Term

• Current Assignee: Johnson & Johnson Medical Incorporated (Johnson & Johnson)
• Original Assignee: UAB Research Foundation (University of Alabama System)
• Inventors: Osborn, John J.
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US05/894,189
• Time in Patent Office: 740 Days
• Field of Search: 128/2.07, 128/2.08, 128/2 C, 128/718, 128/719, 128/750, 73/421.5 R, 23/232 R, 23/232 B, 422/83, 422/84
• US Class Current: 600/531
• CPC Class Codes: A61B 5/0876 using means deflected by the fluid stream, e.g. flaps
• CPC Class Codes: G01F 1/36 the pressure or differential pressure being created by the use of flow constriction
• CPC Class Codes: G01F 1/40 Details of construction of the flow constriction devices
• CPC Class Codes: G01N 33/497 of gaseous biological material, e.g. breath

Abstract

A system for measuring the oxygen uptake and respiratory quotient of a patient which employs a high resistance gas flow path in parallel with a pneumotachograph. The high resistance path is connected to each side of the pneumotachograph and a small chamber is included in the high resistance path at each end thereof adjacent its connection to the pneumotachograph. The volume of the high resistance path, together with its resistance relative to that of the pneumotachograph is chosen such that, during respiration of the patient employing the device, the high resistance path will never be completely flushed through in one direction before flow starts in the opposite direction. The high reistance path is chosen to be a constant resistance such that the amount of flow therethrough is proportional to the flow through the pneumotachograph. Thus by sampling and analyzing a small portion of the gas of the two chambers and measuring the amount of gas flow by the pneumotachograph, the exact amount of oxygen uptake can be calculated.

Claims

1. Apparatus for use in a system for measuring oxygen uptake and the like comprising first conduit means for conducting flow of respiration gases to and from a patient, said first conduit means including first flow resistance means, second conduit means having one end thereof in communication with said first conduit means on one side of said first flow resistance means and the other end thereof in communication with said first conduit means on the other side of said first flow resistance means, said second conduit means including second flow resistance means, the volume of said second conduit means being substantially greater than the volume of gases conducted therethrough by a single breath of the patient whereby flushing of the second conduit means is precluded, and sampling means coupled adjacent the ends of said second conduit means for analyzing the gases therein.

2. Apparatus as defined in claim 1 wherein said second flow resistance means affords substantially greater resistance to the flow of gases than said first flow resistance means.

3. Apparatus as defined in claim 1 wherein said first flow resistance means comprises the flow resistance of a pneumotachograph.

4. Apparatus as defined in claim 1 wherein said second flow resistance means comprises an elongated tube.

5. Apparatus as defined in claim 1 wherein said second flow resistance means comprises a series of elongated tubes arranged in parallel.

6. Apparatus as defined in claim 1 wherein said second flow resistance means comprises a housing having inlet and outlet ports and an orifice membrane disposed across the interior of said housing between said inlet and outlet ports, said orifice membrane being formed of an elastic material, said orifice membrane defining an orifice, a flap disposed within and substantially coextensive with said orifice and having one edge thereof integral with said membrane to thereby form a hinged connection between said flap and said membrane, said flap including sides which converge to form the narrowest portion of the flap at that portion thereof most remote from the hinged connection to the orifice membrane, said hinged connection being narrower than the widest portion of said flap.

7. Apparatus as defined in claim 1 wherein said first and second flow resistance means each provide a constant resistance to the flow of respiration gases over a wide range of flow velocity.

8. Apparatus as defined in claim 1 wherein said second flow resistance means affords resistance to the flow of gases fifty times greater than does said first flow resistance means.

9. Apparatus as defined in claim 1 wherein said second flow resistance means affords resistance to the flow of gases one hundred times greater than does said first flow resistance means.

10. Apparatus as defined in claim 1 wherein said second conduit means comprises a first chamber at one end thereof and a second chamber at the other end thereof, said second flow resistance means being disposed in communication between said chambers, said sampling means being coupled to said chambers.

11. Apparatus as defined in claim 10 together with baffle means disposed within said first and second chambers.