Process for pheresis procedure and disposable plasma
First Claim
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1. A blood pheresis process, comprising the steps of:
- (a) withdrawing whole blood from a donor through phlebotomy needle means connected to said donor and simultaneously admixing anticoagulant therewith;
(b) introducing the resulting anticoagulated whole blood by way of a fluid conduit system into the bottom of a first reservoir while said reservoir is rotating about an axis of rotation;
(c) rotating said first reservoir at centrifuging speed thereby to separate the plasma in said blood from the red cells;
(d) transferring the resulting separated plasma to a second reservoir affixed coaxially to said first reservoir and rotating about said axis of rotation therewith;
(e) stopping said rotating so that the red cells settle to the bottom of the first reservoir;
(f) returning said red cells to said donor through said fluid conduit system, the connection between said donor, said fluid conduit system, and said first reservoir being maintained throughout steps (a)-(f); and
(g) separating said second reservoir from said first reservoir in a manner to aseptically seal said plasma within said second reservoir.
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Abstract
A pheresis process and apparatus for carrying it out. Blood from a donor is transferred to a pheresis bowl formed to have a red cell reservoir and a plasma reservoir in fluid communication through plasma ducts. The pheresis bowl is adapted for centrifuging to separate the red cells and plasma. This separation is accomplished simultaneously with the withdrawal of blood from the donor. At the end of the withdrawal the red cells are returned to the donor. The connection with the donor is thus continuously maintained during the entire procedure. The process is safe, fast and economical.
100 Citations
4 Claims
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1. A blood pheresis process, comprising the steps of:
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(a) withdrawing whole blood from a donor through phlebotomy needle means connected to said donor and simultaneously admixing anticoagulant therewith; (b) introducing the resulting anticoagulated whole blood by way of a fluid conduit system into the bottom of a first reservoir while said reservoir is rotating about an axis of rotation; (c) rotating said first reservoir at centrifuging speed thereby to separate the plasma in said blood from the red cells; (d) transferring the resulting separated plasma to a second reservoir affixed coaxially to said first reservoir and rotating about said axis of rotation therewith; (e) stopping said rotating so that the red cells settle to the bottom of the first reservoir; (f) returning said red cells to said donor through said fluid conduit system, the connection between said donor, said fluid conduit system, and said first reservoir being maintained throughout steps (a)-(f); and (g) separating said second reservoir from said first reservoir in a manner to aseptically seal said plasma within said second reservoir. - View Dependent Claims (2, 3)
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4. A blood pheresis process, comprising the steps of:
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(a) withdrawing whole blood from a donor through phlebotomy needle means connected to said donor and simultaneously admixing anticoagulant therewith; (b) introducing the resulting anticoagulated whole blood by way of a fluid conduit system into the bottom of a first reservoir while said reservoir is rotating about an axis of rotation; (c) rotating said first reservoir at centrifuging speed thereby to separate the plasma in said blood from the red cells; (d) transferring the resulting separated plasma to a second reservoir affixed coaxially to said first reservoir and rotating about said axis of rotation therewith, the plasma being transferred to a second reservoir through ducts communicating with the tops of each of the first and second reservoirs; (e) stopping said rotating so that the red cells settle to the bottom of the first reservoir; and (f) returning said red cells to said donor through said fluid conduit system, the connection between said donor, said fluid conduit system, and said first reservoir being maintained throughout steps (a)-(f).
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Specification