Synthetic absorbable surgical devices of poly(alkylene oxalates)
First Claim
1. A surgical prosthesis comprising a fabric manufactured at least in part from synthetic absorbable fibers comprising a polymer having a major portion of units of the formula ##STR3## wherein R is a C3 to C16 alkylene and n is the degree of polymerization resulting in a fiber-forming polymer having an inherent viscosity of at least about 0.4 as determined at 25°
- C. on a 0.1 percent solution of polymer in chloroform or hexafluoroisopropanol.
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Abstract
Synthetic filaments composed of homopolymers and copolymers of poly(alkylene oxalates) are absorbable in animal tissue with minimal adverse tissue reaction. Polymers prepared by reacting a dialkyl oxalate with an alkylene diol are melt spun and drawn to obtain oriented fibers having good tensile properties and a high level of flexibility and softness. The filaments are particularly useful in the preparation of surgical prosthesis comprising woven or knitted fabrics and meshes. Other absorbable surgical devices including films and molded items may also be prepared from the disclosed polymer.
349 Citations
9 Claims
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1. A surgical prosthesis comprising a fabric manufactured at least in part from synthetic absorbable fibers comprising a polymer having a major portion of units of the formula ##STR3## wherein R is a C3 to C16 alkylene and n is the degree of polymerization resulting in a fiber-forming polymer having an inherent viscosity of at least about 0.4 as determined at 25°
- C. on a 0.1 percent solution of polymer in chloroform or hexafluoroisopropanol.
- View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A surgical prosthesis comprising a solid surgical aid, cast or machined from an absorbable polymer having a major portion of units of the formula ##STR4## wherein R is a C3 to C16 alkylene and n is the degree of polymerization resulting in a polymer having an inherent viscosity of at least 0.4 determined at 25°
- C. on a 0.1 percent solution of polymer in chloroform or hexafluoroisopropanol.
- View Dependent Claims (9)
Specification