Incubator for chemical analyzer

• US 4,219,529 A
• Filed: 11/28/1977
• Issued: 08/26/1980
• Est. Priority Date: 11/28/1977
• Status: Expired due to Term

• Current Assignee: Clinical Diagnostic Systems Inc.
• Original Assignee: Eastman Kodak Company
• Inventors: Meyer, Robert J., Whitcomb, Rodney J., Tersteeg, Glenn E., Nosco, Louis C.
• Primary Examiner(s): Serwin, R. E.
• Application Number:
  US05/855,124
• Time in Patent Office: 1,002 Days
• Field of Search: 23/230 R, 422/64-66, 195/127, 195/139, 119/35, 119/39, 119/43, 435/809
• US Class Current: 422/65
• CPC Class Codes: B01L 7/00 Heating or cooling apparatus autoclaves B01J3/04; Heat insulating devices
• CPC Class Codes: G01N 1/312 for samples mounted on planar substrates
• CPC Class Codes: G01N 2035/00049 for loading/unloading a carousel
• CPC Class Codes: G01N 2035/00089 Magazines
• CPC Class Codes: G01N 2035/00356 Holding samples at elevated temperature (incubation)
• CPC Class Codes: G01N 35/00029 provided with flat sample substrates, e.g. slides G01N35/028 takes precedence
• CPC Class Codes: Y10S 435/809 Incubators or racks or holders for culture plates or containers

Abstract

An incubator is provided for use with a chemical analyzer of the type in which a fluid sample is metered onto a test slide which is analyzed after a suitable period of incubation. The incubator includes a temperature-controlled chamber having a conveyor mounted therein which comprises a plurality of slide holding members. A drive means for the conveyor is adapted to successively advance the slide holding members past load and unload slots located adjacent slide transfer mechanisms.

Claims

1. An incubator for use in a chemical analyzer in which a fluid sample is metered onto a slide which is analyzed after an appropriate period of incubation, said incubator comprising:

means which defines a temperature controlled chamber, said chamber having a first location wherein slides are transferred into the chamber and a second location wherein slides are transferred out of the chamber;

rotor means in said chamber, said rotor means including a plurality of radially-extending slide holding means for releasably holding the slides in the rotor means; and

drive means for said rotor means, said drive means being adapted to effect movement of slides in the rotor means within said chamber, and said drive means being further adapted to stop said rotor means in a position such that slides can be transferred at either of said locations.

2. An incubator, as defined in claim 1, wherein said means for defining a temperature controlled chamber comprises a first side wall mounted on one side of said rotor means and a second side wall mounted on an opposite side thereof, a load slot is in said first side wall at said first location, an unload slot is in said second wall at said second location, and said slots are in alignment with each other.

3. An incubator, as defined in claim 1, wherein said drive means comprises a worm which is coupled to said rotor means, and a thread portion of said worm is disposed at a zero helix angle.

4. An incubator, as defined in claim 2, wherein said rotor means moves the slides about an axis generally parallel to the direction of slide movement into and out of said chamber.

5. An incubator, as defined in claim 2, wherein analysis means is located adjacent said unload slot, and a slide transfer mechanism adjacent said unload slot is adapted to simultaneously move a first slide out of said rotor means and into said analysis means and a second slide out of said analysis means and into a discharge chute.

6. An incubator, as defined in claim 5, wherein each of said slide holding means comprises a support member and a spring clip mounted thereon, said clip having a portion which is adapted to be biased against a slide on the support member, said slide transfer mechanism comprises a claw mechanism having a pair of members, one of said members being located radially outward of said portion and the other member being located radially inward of said portion whereby said members are on opposite sides of the portion when the claw mechanism is in contact with the slide on said support member.

7. An incubator, as set forth in claim 6, wherein said preheater means comprises a heated portion of said means for loading slides into said carrier.

8. An incubator, as set forth in claim 6, wherein said preheater means comprises a heated surface which the slides contact during movement to the conveyor.

9. An incubator for use in a chemical analyzer of the type in which a fluid sample is metered onto a test slide which is analyzed after an appropriate period of incubation, said incubator comprising:

a housing which defines a temperature controlled chamber, said housing having a load slot on one wall thereof and an unload slot on an opposite wall, said slots being directly opposite each other;

a rotor mounted for rotation within said chamber, said rotor comprising a plurality of radially extending slide holding means; and

drive means for said rotor, said drive means being adapted to successively move said slide holding means between said slots and to stop a selected one of said slide holding means in a position relative to said slots wherein a processed slide is unloaded from said one slide holding means through said unload slot and a new slide is loaded into said one slide holding means through said load slot.

10. An incubator as set forth in claim 9, wherein the rotor rotates about an axis which is generally parallel to the direction of movement of slides through said load and unload slots.

11. An incubator, as defined in claim 9, wherein a preheater is mounted adjacent said one wall and in communication with said load slot, said preheater comprising first and second elements which define a confined space slightly larger than a slide, said first element being adapted to be heated to a controlled temperature, and said second element being movable relative to said first element to permit entry of a slide into said preheater.

12. An incubator, as recited in claim 11, wherein said drive means comprises a rotor drive shaft, a ring gear mounted on said shaft, and a worm which cooperates with said ring gear, said worm including a thread having a zero helix angle in each 360 degree extension thereof.

13. An incubator, as recited in claim 12, wherein said slide holding means comprises a plurality of support members extending radially from a hub of said rotor, a spring clip is mounted on each of said members, each of said clips having a forward edge portion, and each of said clips being adapted to be cammed away from a surface on said member by the action of slide on said edge portion as the slide enters the rotor from said load slot.

14. An incubator for use in a chemical analyzer in which a fluid sample is metered onto a slide which is analyzed after an appropriate period of incubation, said incubator comprising:

a circular conveyor for moving slides through a rotary path;

means enclosing said conveyor to provide a controlled environment for slides during such movement;

means for loading slides bearing said fluid sample into said conveyor through a load slot in said enclosing means; and

slide preheater means disposed adjacent said load slot for receiving slides and raising the temperature thereof prior to movement of the slides into said incubator.