Composite implant materials and process for preparing same

• US 4,222,128 A
• Filed: 05/08/1978
• Issued: 09/16/1980
• Est. Priority Date: 05/20/1977
• Status: Expired due to Term

• Current Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
• Original Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
• Inventors: Aoki, Hideki, Tomonaga, Atsushi
• Primary Examiner(s): McCarthy, Helen M.
• Application Number:
  US05/903,579
• Time in Patent Office: 862 Days
• Field of Search: 106/39.5, 106/35, 32/8, 32/10 A, 3/1.9, 3/1.91, 128/92 R, 128/92 C, 427/2, 427/385 R, 427/385 B, 433/201
• US Class Current: 623/23.51
• CPC Class Codes: A61C 8/0012 characterised by the material or composition, e.g. ceramics, surface layer, metal alloy use of specific materials A61K6/00
• CPC Class Codes: A61C 8/0016 polymeric material
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2002/30065 thermoplastic, i.e. softening or fusing when heated, and hardening and becoming rigid again when cooled
• CPC Class Codes: A61F 2002/30224 cylindrical
• CPC Class Codes: A61F 2002/30968 Sintering
• CPC Class Codes: A61F 2210/0071 thermoplastic
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2310/00293 containing a phosphorus-containing compound, e.g. apatite
• CPC Class Codes: A61L 27/12 Phosphorus-containing materials, e.g. apatite
• CPC Class Codes: A61L 27/44 having a macromolecular matrix
• CPC Class Codes: A61L 27/46 with phosphorus-containing inorganic fillers

Abstract

Disclosed is a composite implant material comprising a sintered apatite material and a thermoplastic or thermosetting resin. Said composite material is prepared by forming a sintered apatite material and filling or impregnating a thermoplastic or thermosetting resin into the pores or holes of the sintered apatite material, which have been formed during the formation of said sintered material or perforated after the formation thereof. Said composite implant material has controlled compatibility to bone as well as excellent physical strength.

Claims

1. A composite implant material usable as a prosthesis for a bone or tooth, comprising a perforated sintered apatite material having perforation holes formed therein in a desired configuration and a thermoplastic or thermosetting resin, at least said perforated sintered apatite material existing in a continuous phase, said resin being filled or impregnated into said holes, and the respective phases of said sintered apatite material and said resin being exposed, in part, to the surface of said implant material.

2. A composite implant material according to claim 1, wherein said sintered apatite material comprises hydroxyapatite.

3. A composite implant material according to claim 1, wherein said thermoplastic or thermosetting resin is selected from the group consisting of polyethylene, polypropylene, polymethyl methacrylate, polyurethane, polyester, acrylonitrile-butadiene-styrene resins, fluorocarbons, polyamides, polyacetals, polycarbonate, polysulfone, epoxy resins, silicone resins, diallyl phthalate resins and furan resins.

4. A composite implant material according to claim 3, wherein said resin contains a reinforcing material selected from carbon, silicon carbide, glass, alumina, magnesia, zirconia, tungsten, molybdenum and stainless steel.

5. A process for preparing a composite implant material according to claim 1, comprising forming a sintered apatite material, perforating the sintered apatite material to form holes in a desired configuration therein, and filling or impregnating a thermoplastic or thermosetting resin into said holes.

6. A process according to claim 5, wherein said sintered apatite material is formed using hydroxyapatite.

7. A process according to claim 5, wherein said thermoplastic or thermosetting resin is selected from the group consisting of polyethylene, polypropylene, polymethyl methacrylate, polyurethane, polyester, acrylonitrile-butadiene-styrene resins, fluorocarbons, polyamides, polyacetals, polycarbonate, polysulfone, epoxy resins, silicone resins, diallyl phthalate resins and furan resins.

8. A process according to claim 5, wherein said sintered apatite material is perforated by mechanical perforation or chemical treatment, or by perforation by means of ultrasonic wave, laser or water jet.