Integrated array of electrochemical sensors

• US 4,225,410 A
• Filed: 12/04/1978
• Issued: 09/30/1980
• Est. Priority Date: 12/04/1978
• Status: Expired due to Term

• Current Assignee: Technicon Instruments Corporation
• Original Assignee: Technicon Instruments Corporation
• Inventors: Pace, Salvatore J.
• Primary Examiner(s): Kaplan, G. L.
• Application Number:
  US05/966,171
• Time in Patent Office: 666 Days
• Field of Search: 364/416, 364/497, 195/127, 204/195 R, 204/195 B, 204/1 E, 422/90, 422/98, 128/2 E, 128/2 G, 128/635
• US Class Current: 204/412
• CPC Class Codes: G01N 33/492 Determining multiple analytes
• CPC Class Codes: Y10S 435/817 Enzyme or microbe electrode

Abstract

A disposable integrated miniaturized array of chemical sensors for analyzing concurrently a number of analytes in a fluid sample is described. Each sensor is a complete electrochemical cell consisting of its own individual reference and indicator electrodes and is selective with respect to a particular analyte in the sample.

Where required, a sensor can be individually calibrated, such that each analysis can be read directly.

Claims

1. An article of manufacture used for analyzing a multiplicity of analytes in a fluid sample, said article comprising an array of discrete, electrically isolated electrochemical sensors supported on a common substrate for analyzing different ones of said analytes, at least one of said sensors in said array having a built in calibrating means including means to establish a differential concentration of an analyte within said one sensor during measurement comprising, a first electrode layer containing a given concentration of the analyte being measured, and a second electrode layer containing a given but different concentration of the analyte being measured, and electrical means to provide access to each of said sensors.

2. The article of manufacture of claim 1, wherein said electrical means comprises electrical conductors supported upon said substrate to provide access to said discrete sensors, said conductors extending to a periphery of said substrate to define a plug-in type connector.

3. The article of manufacture of claim 2, wherein said electrical connectors comprise printed connectors deposited upon a common substrate.

4. The article of manufacture of claim 3, wherein selected ones of said sensors comprise printed electrodes deposited upon said substrate in electrical continuity with respective ones of said printed connectors.

5. The article of manufacture of claim 3, wherein said printed connectors are adapted to be received in a snap-in receptacle of an analyzing means responsive to at least selected ones of said sensors.