Volume flow measurement system

• US 4,227,407 A
• Filed: 11/30/1978
• Issued: 10/14/1980
• Est. Priority Date: 11/30/1978
• Status: Expired due to Term

• Current Assignee: Cornell Research Foundation Incorporated (Cornell University)
• Original Assignee: Cornell Research Foundation Incorporated (Cornell University)
• Inventors: Drost, Cornelis J.
• Primary Examiner(s): Ruehl, Charles A.
• Application Number:
  US05/965,456
• Time in Patent Office: 684 Days
• Field of Search: 73/861.28, 128/663
• US Class Current: 73/861.28
• CPC Class Codes: A61B 5/0275 using tracers, e.g. dye dilution
• CPC Class Codes: G01F 1/66 by measuring frequency, phase shift or propagation time of electromagnetic or other waves, e.g. using ultrasonic flowmeters

Abstract

An apparatus and method for direct measurement of the volume flow of fluids through a tube, using an interferometric transit time technique is disclosed. First and second transducers for producing and receiving waves which are capable of being modified by the flow of the fluid in the conduit are positioned so that the conduit is fully and evenly illuminated by the waves. The transducers are located with respect to the conduit so that there will be a component of fluid flow along the axis of the illuminating wave beam. Means are provided to first activate one transducer to transmit waves while the other is in a receive mode and thereafter to place the second transducer in a transmit mode while the first is switched to its receive mode. The received waves are converted to corresponding electric signals by the corresponding transducers, and these signals are periodically sampled and stored for comparison. The result of this comparison is an electric signal which is proportional to fluid flow and is to a high degree independent of flow profile, conduit geometry, and alignment of the conduit within the probe. The device is particularly useful in measuring the flow of blood through a vessel.

Claims

1. A flow measurement device for obtaining a signal representive of the volume flow of a fluid, comprising:

a first transducer for producing and for receiving acoustic waves capable of being modified by the flow of a fluid;

a second transducer for producing and for receiving acoustic waves capable of being modified by the flow of said fluid;

means for positioning said first and second transducers to illuminate substantially uniformly the entire diameter of said fluid flow by waves produced by said transducers, said transducers being so related that the fluid to be measured will have a component of flow along the axis of said waves;

first means for energizing said first transducer to produce a first beam of said waves for a first period of time in a first direction with respect to said component of flow;

said wave beam being directed to and received by said second transducer to produce first electrical signals representing the received waves;

second means for energizing said second transducer to produce a second beam of said waves for a second period of time in a second direction with respect to said component of flow, said second wave beam being directed to and received by said first transducer to produce second electrical signals representing the received waves;

said first and second means for energizing said first and second transducers comprising oscillator means producing a high frequency electrical output, normally deactivated first and second gate means connecting said oscillator output to said first and second transducers, respectively, and control means for periodically and alternately activating said first and second gate means in transmit modes to produce bursts of acoustic waves which travel between said first and second transducers;

receiver means responsive to said first and second electrical signals produced by said second and first transducers, respectively, said receiver means being connected to said first and second transducers by said first and second gate means, respectively, said control means periodically and alternately activating said gate means in receive modes to permit said first and second electrical signals to travel to said receiver means;

synchronous detector means connected to said receiver means and to said oscillator means for alternately comparing each of said first and second electrical signals with the high frequency output of said oscillator to produce corresponding alternate first and second variable signals;

integrator means for alternately integrating each of said first and second variable signals to produce first and second output signals corresponding to said first and second electrical signals; and

means responsive to the difference between said first and second output signals for producing a resultant signal which is proportional to the volume flow of said fluid.

2. The flow measuring device of claim 1, wherein said means responsive to the difference between said first and second output signals comprises:

a first sample and hold circuit for sampling and storing a valve corresponding to said first output signal;

a second sample and hold circuit for sampling and storing a second value corresponding to said second output signal; and

means for comparing said first and second values, for providing said resultant signal corresponding to the volume flow signal.

3. The flow measuring device of claim 1, wherein said integrator means is a normally deactivated gated integrator, and wherein said control means operates in its receive modes to activate said gated integrator and a selected one of said sample and hold circuits.

4. The flow measuring device of claim 3, wherein said oscillator means includes a normally deactivated gated power amplifier for supplying said high frequency electrical output to said first and second gate means, said control means activating said gated power amplifier only in said transmit mode.

5. The flow measuring device of claim 1, further including housing means defining a cavity and means for mounting said first and second transducers in said housing so that said waves produced by said transducers illuminate the entire cross section of said cavity with a substantially constant wave intensity, said cavity being adapted to receive said fluid flow.

6. The flow measuring device of claim 5, wherein said fluid flows through a conduit, and wherein said cavity is adapted to receive said conduit.

7. The flow measuring device of claim 6, wherein said fluid is blood, and said conduit is a blood vessel, said resultant signal being proportional to the volume flow of said blood and independent of flow profile or vessel wall thickness.

8. The flow measuring device of claim 7, wherein said conduit is of a material which has a wave attenuation comparable to that of said fluid.

9. The volume flow measurement device of claim 1, wherein said first and second transducers are located on diametrically opposed sides of the flow path of said fluid.

10. The volume flow measurement device of claim 1, wherein said first and second transducers are located on the same side of the flow path of said fluid, said device further including a wave reflective surface aligned with the waves transmitted by said transducers and located on the side of said flow path diametrically opposed to the location of said transducers, said transducers and said reflective surface being angularly related so that the beam of waves produced by one transducer will be received by the other transducer after reflection from said reflective surface, whereby the beam of waves will pass twice through said fluid flow path.

11. A flow measurement system for obtaining a resultant signal representative of the volume flow of a fluid stream, comprising:

first and second acoustic wave transducers adapted to be located adjacent the fluid stream, said transducers being so located that an acoustic wave beam transmitted by one transducer will pass through said fluid stream and will impinge on the other transducer;

means for generating a drive signal for activating said transducers, said drive signal being of an amplitude and frequency sufficient to drive said transducers to produce ultrasonic wave beams, said transducers each producing a wave beam of sufficient dimension to illuminate with uniform intensity tne entire cross section of the portion of the fluid stream to be measured;

control means for periodically and alternately switching said transducers between transmit and a receive modes, whereby said drive signal is applied to said first transducer and the resulting acoustic wave beam is received by said second transducer and thereafter said drive signal is applied to said second transducer and the resulting acoustic wave beam is received by said first transducer;

synchronous detector means for comparing the signal received by said second transducer with said drive signal to provide a first variable signal and for comparing the signal received by said first transducer with said drive signal to provide a second variable signal;

means for integrating each of said first and second variable signals to produce first and second output signals; and

means responsive to the difference between said first and second output signals for producing a resultant signal which is proportional to the volume flow of said fluid stream.

12. The flow measurement system of claim 11, wherein said transducers are so located with respect to said fluid stream that said wave beam transmitted by said first transducer passes through said fluid at an upstream angle, and said wave beam transmitted by said second transducer passes through said fluid at a downstream angle, and wherein said first output signal is proportional to the transit time of said first beam and said second output signal is proportional to the transit time of said second beam, said resultant signal being proportional to the difference in transit times, and this proportional to fluid volume flow.

13. The flow measurement system of claim 11, wherein said means responsive to the difference between said first and second output signals includes first and second sample and hold circuits.