Gas exchange apparatus

• US 4,228,125 A
• Filed: 06/20/1978
• Issued: 10/14/1980
• Est. Priority Date: 06/20/1978
• Status: Expired due to Term

• Current Assignee: COBE Laboratories Incorporated (Terumo Corporation)
• Original Assignee: COBE Laboratories Incorporated (Terumo Corporation)
• Inventors: Herman, Stephen J., Lobdell, Donn D.
• Primary Examiner(s): Richman, Barry S.
• Application Number:
  US05/917,350
• Time in Patent Office: 847 Days
• Field of Search: 422/46, 422/47, 195/1.8, 261/128, 261/152, 261/123, 261/124, 261/126, 261/DIG. 28, 128/DIG. 3, 55/255, 55/256, 435/2
• US Class Current: 422/46
• CPC Class Codes: A61M 1/32 Oxygenators without membranes
• CPC Class Codes: A61M 1/325 Surfactant coating; Improving wettability
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: Y10S 128/03 Heart-lung
• CPC Class Codes: Y10S 261/28 Blood oxygenators

Abstract

Diffusing gas into and out of a liquid at a uniform rate by distributing a foam consisting of bubbles with liquid walls surrounding the gas through elongated passages defined by a corrugated surface adjacent to a smooth surface, while simultaneously providing for indirect heat - exchange of the blood foam while the foam is within the elongated passages.

Claims

1. A blood oxygenator comprising

foaming means for bubbling gas into blood to form a foam composed of bubbles, each bubble having a wall formed of said blood,

heat and gas exchanging means located downstream of said foaming means, said heat and gas exchanging means comprising

a heat-conductive corrugated sheet having first and second opposing surfaces,

a housing adjacent said first opposing surface and defining therebetween a chamber for passing heat-transfer fluid along said first surface, said housing having an inlet for connection to a heat-transfer fluid source and an outlet for removing said heat-transfer fluid from said chamber, the flow through said chamber being isolated from said second opposing surface, and

a wall surface adjacent to said second opposing surface, said wall surface and said second surface defining a plurality of passages corresponding to the corrugations in said sheet, said passages distributing said foam into a corresponding plurality of streams and providing locations for simultaneous

heat transfer between said fluid and said foam and

gas transfer between said gas and said blood at the walls of said bubbles, and

defoaming means located downstream of said heat and gas exchanging means for breaking up said bubbles.

2. The apparatus of claim 1 wherein said liquid is blood and said passages defined by said corrugated surface and smooth surface are oblong in transverse cross-section with a ratio of larger transverse dimension to smaller transverse dimension of between 3 and 10.

3. The apparatus of claim 1 wherein the size of said passages is adapted to make uniform the size of said bubbles.

4. The apparatus of claim 1 wherein said passages are vertical.

5. The apparatus of claim 1 wherein said smooth surface is planar and parallel with a plane defined by peaks of the corrugations in said corrugated surface.

6. The apparatus of claim 1 wherein said peaks of said corrugated surface closest to said smooth surface either touch said smooth surface or are separated therefrom by a gap up to 0.04 inches.

7. The apparatus of claim 1 wherein said corrugated sheet is a metal sheet.

8. The apparatus of claim 1 wherein the ratio of the longitudinal dimension of each of said passages to the smaller transverse dimension is between 100 and 300.

9. The apparatus of claim 8 wherein the smaller transverse dimension of each of said passages varies between 0.055 and 0.070 inches.

10. The apparatus of claim 8 wherein the longitudinal dimension of each of said passages is between 10 and 12 inches.