Physiologically adaptive cardiac pacemaker
First Claim
1. A demand cardiac pacemaker having circuitry for carrying out demand pacer functions, adapted to be utilized in combination with an electrode for delivering stimulus signals to a patient'"'"'s heart and for receiving from said patient'"'"'s heart signals representative of heart activity, comprising:
- a. stimulus signal generator means for delivering stimulus signals, having modifiable means for setting its escape interval;
b. T wave means for sensing a T wave of an evoked heart response following a delivered stimulus signal, and for determining the time relationship of said T wave relative to said delivered stimulus signal; and
c. modifying means connected to said T wave means and said modifiable means for modifying said escape interval as a function of said time relationship.
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Accused Products
Abstract
A cardiac pacemaker is disclosed having means for automatically adjusting the rate of operation to correspond to physiological changes. Circuitry is provided for detecting the presence or absence of an evoked T wave following a delivered stimulus pulse, and for measuring the time interval between the stimulus pulse and the following T wave. The escape interval of the pacemaker pulse generator is varied in accordance with the detected stimulus-T interval and in the same direction, so as to vary the pacing rate in accordance with variations in such interval. Since this interval in turn corresponds to physiological changes, the pacemaker is adapted to automatically follow the patient'"'"'s physiological changes.
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Citations
37 Claims
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1. A demand cardiac pacemaker having circuitry for carrying out demand pacer functions, adapted to be utilized in combination with an electrode for delivering stimulus signals to a patient'"'"'s heart and for receiving from said patient'"'"'s heart signals representative of heart activity, comprising:
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a. stimulus signal generator means for delivering stimulus signals, having modifiable means for setting its escape interval; b. T wave means for sensing a T wave of an evoked heart response following a delivered stimulus signal, and for determining the time relationship of said T wave relative to said delivered stimulus signal; and c. modifying means connected to said T wave means and said modifiable means for modifying said escape interval as a function of said time relationship. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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- 11. In a demand pacer having a stimulus generator with an adjustable escape interval for delivering pacing stimuli, said pacer being adapted to receive signals representative of heart activity, the improvement consisting of means for setting said escape interval as a function of the time interval between a pacing stimulus delivered by said pacer and the evoked heart repolarization following such delivered stimulus.
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21. A pacing system having a demand pacemaker with a stimulus generator for normally delivering stimulus signals at a normal rate and means for resetting said stimulus generator upon detection of a natural heartbeat, in combination with an electrode adapted to deliver stimulus signals to a heart and to provide signals representative of activity of said heart, said pacemaker being characterized by
a. said stimulus generator having a circuit providing an adjustable escape interval, and b. comprising means for detecting the time relationships between delivered stimulus signals and the corresponding T waves following such delivered stimulus signals, and means for setting the escape interval of said stimulus generator as a function of said detected time relationships.
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25. A demand cardiac pacer having a stimulus generator for generating stimulus pulses and demand logic circuitry for resetting said stimulus generator upon detection of a signal representing a natural heartbeat, further characterized by:
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means for sensing T wave signals; means for determining the time interval between a stimulus pulse and the following evoked T wave signal, and for generating a modifying signal corresponding to said time interval; and means for modifying the escape interval of said stimulus generator with said modifying signal.
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26. A method of cardiac pacing of a patient wherein the rate of pacing is adapted to react to physiological changes, comprising:
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generating a first stimulus pulse and delivering said first stimulus pulse to said patient'"'"'s heart, thereby evoking a heartbeat, said heartbeat including a QRS wave and a T wave; sensing said T wave of said evoked heartbeat; measuring the time interval between said T wave and a prior time reference point; and
thendelivering a next stimulus pulse after a second time interval which is a predetermined function of said determined time interval. - View Dependent Claims (27)
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28. A cardiac pacemaker adapted to react to physiological changes of the patient being paced by such pacemaker, comprising:
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stimulus generator means for generating stimuli for delivery to the patient'"'"'s heart, said stimulus generator means having a variable escape interval; means for developing a signal corresponding to the QRS-T interval of a heart signal evoked by one of said stimuli; and means for varying said escape interval for the next subsequent stimulus as a function of said corresponding signal, thereby controlling the rate of said stimulus generator in accordance with said patient'"'"'s changing QRS-T interval. - View Dependent Claims (29)
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30. A method of cardiac pacing of a human patient, comprising:
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normally delivering stimulus signals to said patient; utilizing an electrode in contact with said patient'"'"'s heart for delivering stimulus signals thereto; utilizing the same electrode for sensing the occurrence of natural QRS signals generated in said patient'"'"'s heart, and inhibiting the delivery of the next said normally delivered stimulus signal following each sensed QRS signal; utilizing the same electrode to sense the evoked T wave signal following delivery of a stimulus signal; determining the time of delivering the next stimulus signal as a function of the timing of said sensed T wave signal; and delivering the next stimulus pulse at said determined time.
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31. A cardiac pacemaker system comprising:
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a stimulus generator circuit characterized by normally operating to generate successive pacing stimuli, said generator circuit having an escape interval circuit which controls the generator escape interval and thus the time rate of successive stimuli; a circuit for measuring the stimulus-T wave interval for evoked heartbeats and for providing at its output a signal corresponding to said interval; connecting circuitry connecting pacing stimuli to an output adapted for connection to a pacing electrode, and for connecting said output to said measuring circuit; a pacing electrode connected to said output and adapted to deliver said pacing stimuli to a patient'"'"'s heart and to deliver signals representative of the patient'"'"'s heart activity to said output; and a circuit connected between said measuring circuit output and said escape interval circuit for modifying the operation of said escape interval circuit so as to control said escape interval.
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32. A cardiac pacer having a stimulus generator with an adjustable escape interval for delivering pacing stimuli, said pacer having means for receiving signals representative of heart activity, wherein the improvement comprises means for detecting the T wave component of heart signals and means for setting said escape interval as a function of the time interval between the last delivered pacing stimulus and the detected T wave following said last delivered pacing stimulus.
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33. A demand cardiac pacemaker having circuitry for carrying out demand pacer functions, adapted to be utilized in combination with an electrode for delivering stimulus signals to a patient'"'"'s heart and for receiving from said patient'"'"'s heart signals representative of heart activity, wherein the improvement comprises:
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a. stimulus signal generator means for delivering stimulus signals, having modifiable means for setting its escape interval; b. sensing means for sensing the T wave portion of the heartbeat signal of an evoked heart response following a delivered stimulus signal and deriving a signal therefrom, and for determining the time relationship of said derived signal relative to said delivered stimulus signal; and c. modifying means connected to said sensing means and said modifiable means for modifying said escape interval as a function of said time relationship. - View Dependent Claims (34, 35, 36, 37)
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Specification