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Somatostatin analogues

  • US 4,230,617 A
  • Filed: 07/05/1979
  • Issued: 10/28/1980
  • Est. Priority Date: 07/05/1979
  • Status: Expired due to Term
First Claim
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1. A compound of the formula:

  • ##STR3## its linear precursor intermediates or non-toxic acid addition salts thereof in whichX2 is NH2, Ala-Gly-, Ala-D-Ala, Gly-Gly-Gly-, lower alkanoyl or benzoyl;

    X4 is Arg, His, D-Arg, or D-His;

    X5 is His, Tyr, Glu, D-His, D-Tyr, or D-Glu;

    X7 is Trp, Tyr, Met, or His;

    andX8 is Trp or D-Trp.

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