Procedure and device for the detection of extraordinary events in a series of essentially periodically recurring normal events

• US 4,231,374 A
• Filed: 10/23/1978
• Issued: 11/04/1980
• Est. Priority Date: 11/07/1977
• Status: Expired due to Term

• Current Assignee: Siemens AG
• Original Assignee: Siemens AG
• Inventors: Weigert, Kurt, Hudek, Karl
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US05/953,896
• Time in Patent Office: 743 Days
• Field of Search: 128/702, 128/703, 128/706, 128/707
• US Class Current: 600/515
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/364 Detecting abnormal ECG interval, e.g. extrasystoles, ectopic heartbeats
• CPC Class Codes: G01R 15/09 Autoranging circuits
• CPC Class Codes: G01R 23/00 Arrangements for measuring frequencies; Arrangements for analysing frequency spectra
• CPC Class Codes: G01R 29/027 Indicating that a pulse characteristic is either above or below a predetermined value or within or beyond a predetermined range of values

Abstract

In an illustrative embodiment EKG normal pulses have a time separation representing a monitoring interval, and upon the occurrence of a normal event (normal pulse), circuitry is activated to determine whether further events occur during the monitoring interval. The monitoring interval can be set at a constant value or a variably concomitant value as a function of the interval between the periodic normal events. Upon switching over from constant value to concomitant value of the monitoring interval, a comparator is activated, which comparator compares a time interval value between periodic normal events determined by means of a frequency-voltage converter with the constant value of the monitoring interval. A regulating element controls the converter output voltage by means of amplification alteration in such manner that it is altered toward the direction of the constant value of monitoring interval. Upon equality, the comparator generates a shutdown signal. The voltage value of the frequency-voltage converter serves then, after shutdown of the regulation upon attainment of the now-constant amplification factor, for the concomitant setting of the monitoring interval. Thus, the setting follows largely automatically, so that the correct value sets itself.

Claims

1. Procedure for the detection of extraordinary events in a series of essentially periodically recurring normal events, particularly extra systoles in the EKG, said procedure comprising:

manually setting a control (1) to a selected fixed value representing a time period corresponding to a fixed monitoring interval between successive occurrences of a normal event,

in a first mode of operation responding to each occurrence of the normal event to begin scanning for a further event, and continuing such scanning for a fixed time duration which corresponds to said selected fixed value, and so monitoring for a further event after each normal event directly according to said selected fixed value so long as the first mode of operation continues, shifting over from said first mode of operation to a second mode of operation, and during said second mode of operation;

(a) activating a comparator circuit (17, 18,

     28) with the compartor having a first input (29) receiving a signal in accordance with said selected fixed value from the control (1) and having a second input (27) connected with a voltage regulator (22,

     23),

(b) monitoring the actual repetition rate of currently occurring normal events by means of a frequency to voltage converter (24),

(c) supplying the output of the frequency to voltage converter (24) to said voltage regulator (22,

     23) with the output of the voltage regulator being connected to the second input (27) of he comparator circuit (17, 18,

     28),

(d) step by step adjusting the amplification factor of the voltage regulator (22,

     23) until the output therefrom as supplied to the second input (27) of the comparator circuit matches the signal at the first input (29) thereof,

(e) responding to the matching at the first and second inputs of the comparator circuit (17, 18,

     28) to fix the amplification factor at the currently adjusted value, and

(f) thereafter during said second mode of operation supplying the output of the voltage regulator (22,

     23) with the amplification factor thereof adjusted according to steps (d) and (e) as a control value representing the time duration of a concomitantly variable monitoring interval, and thereafter responding to each occurrence of the normal event to begin scanning for an extraordinary event, and continuing such scanning for a time duration which is a function of said control value during said second mode of operation.

2. Apparatus for the implementation of the procedure according to claim 14, comprising

manually adjustable control means (1) for selecting a selected fixed value representing a time period corresponding to a fixed monitoring interval between successive occurrences of a normal event,

switchover means (2) for selecting between a first mode of operation and a second mode of operation,

monitoring means (3, 5-13) connected with said manually adjustable control means (1) under the control of said switchover means (2) and operable in the first mode of operation as selected by said switchover means (2) to respond to each occurrence of the normal event to begin scanning for a further event, and continuing such scanning for a fixed time duration which corresponds to said selected fixed value, and so monitoring for a further event after each normal event directly according to said selected fixed value so long as the first mode of operation continues,

comparator circuit means (17, 18, 28) comprising a comparator (28) having a first input (29) connected with said control means (1) for receiving a signal in accordance with said selected fixed value, and having a second input (27),

voltage regulator means (22, 23) having a frequency to voltage converter (24) for supplying a signal to said regulator means (22, 23) in accordance with the frequency of occurrence of normal events, having step by step amplification adjusting means (19-21) connected therewith for controlling the amplification factor thereof, and having an output connected to the second input (27) of said comparator (28), and also connected under the control of said switchover means with said monitoring means (3, 5-9, 11-13) so that in said second mode of operation as selected by said switchover means (2) the output of said regulator means (22, 23) is supplied to said monitoring means,

said comparator circuit means (17, 18, 28) being responsive to switchover of said switchover means (2) to said second mode of operation to activate said step by step amplification adjusting means (19-21) to progressively change the amplification factor of the regulator means (22, 23) until said comparator (28) signals a match between its first and second inputs,

said monitoring means (3, 5-9, 11-13) thereafter during said second mode of operation responding to each occurrence of the normal event to begin scanning for an extraordinary event, and being responsive to the output of said regulator means (22, 23) to continue such scanning for a time duration which is a function of the output of said frequency to voltage converter (24) and the amplification factor of said regulator means as set by said step by step amplification adjustment means (19-21), thereby to provide a concomitantly variable monitoring interval.

3. Apparatus according to claim 2, with the voltage regulator means comprising a voltage amplifier (23), and a negative feedback network (22) connected between the output and the input of said voltage amplifier (23), and said step by step amplification adjusting means being operable for changing the value of the resistance of said feedback network (22) during said second mode of operation in successive steps such that the amplification factor of the voltage amplifier (23) changes step by step and generates an output voltage that rises in a step form.

4. Apparatus according to claim 3 with said step by step amplification adjusting means comprising a binary counter (20) controlling said negative feedback network (22), said negative feedback network (22) comprising a series of resistors which are connected to one another in accordance with the count of said binary counter (20).

5. Apparatus according to claim 4 with said comparator circuit means comprising a monostable flip-flip (17) connected with said binary counter (20) and responsive to switchover to said second mode of operation to set and binary counter (20) to a count initiation value.

6. Apparatus according to claim 3 with said step by step amplification adjusting means comprising a counter (20) controlling the value of the resistance of said resistance network (22) in accordance with the count thereof, and a clock generator (21) for connection with said counter (20), and a switching element (19) controlling connection of said clock generator (21) with said counter (22), said comparator circuit means comprising a bistable flip-flop (18) controlling said switching element (19), and a monostable flip-flop (17) connected with said bistable flip-flop (18) and responsive to selection of said second mode of operation by said switchover means (2) to set said bistable flip-flop to an active state and thereby to actuate said switching element (19) to initiate a step by step amplification adjustment cycle.

7. Apparatus according to claim 6 with said comparator (28) being connected with said bistable flip-flop (18) for resetting the bistable flip-flop (18) out of its active state when a match is attained between the first and second inputs of said comparator to stop the counting of said counter so that the resistance value of said negative feedback network (22) is held constant and thereby the amplification factor of the voltage regulator means is held constant corresponding to the attained count of said counter (20).

8. Apparatus according to claim 2 with said monitoring means comprising a setting mechanism (3, 5, 7-13) connected with said control means (1) in said first mode of operation, and connected with said voltage regulator means (22, 23) in said second mode of operation, and being responsive to the fixed value selected by said control means (1) to set the time period of the fixed monitoring interval in accordance therewith in said first mode of operation, an interlock switch (6) responsive to an interlock signal for controlling said setting means for preventing change of said time period thereby, said comparator circuit means (17, 18, 28) being connected with said interlock switch (6) and being operable to supply said interlock signal thereto during the activation of the step by step amplification adjusting means (19-21) to suppress operation of the setting mechanism (3, 5, 7-13).

9. Apparatus according to claim 8 with said comparator circuit means (17, 18, 28) being responsive to a match at the first and second inputs of said comparator (28) to interrupt supply of said interlock signal to said interlock switch (6), thereby to place said setting mechanism (3, 5, 7-13) in operation for setting of the duration of the scanning for a further event in accordance with the output from said voltage regulator means (22, 23).

10. Apparatus according to claim 8 with said comparator circuit means comprising a monostable flip-flop (17) responsive to switchover to said second mode of operation to supply an output signal,

a bistable flip-flop (18) connected with said interlock switch (6) and responsive to the output signal from said monostable flip-flop (17() to supply said interlock signal to said interlock switch (6),

said bistable flip-flop (18) being connected with the comparator (28) and being responsive to a match at the first and second inputs thereof to interrupt said interlock signal.

11. Apparatus according to claim 2 with said frequency to voltage converter (24) having an interlock switch (25) controlling the input thereto, and said monitoring means (3, 5-13) being connected with said interlock switch (25) for actuating said switch to suppress admission of pulse events to said frequency to voltage converter (24) for the duration of a concomitantly variable monitoring interval.

12. Apparatus according to claim 2, with said monitoring means comprising an analog-digital converter (3) selectively connectable with said control means (1) and with said voltage regulator means (22, 23) as selected by said switchover means (2), comparison means (13) having a first input for connection with said analog-digital converter (3) for receiving a digitalized voltage value in accordance with the output of said analog-digital converter (3) and having a second input, and a counter unit (11, 12) connected with said second input of said comparison means (13) and operable in conjunction with said comparison means (13) for establishing a time interval proportional to the digitalized voltage value at the first input of said comparison means (13), thereby to define the time duration of a concomitantly variable monitoring interval.