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Liquid chromatography apparatus

  • US 4,233,156 A
  • Filed: 03/07/1979
  • Issued: 11/11/1980
  • Est. Priority Date: 03/10/1978
  • Status: Expired due to Term
First Claim
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1. A liquid chromatography apparatus comprising:

  • at least one reservoir for storing at least one liquid mobile phase;

    at least one valve for controlling the liquid mobile phase flowing out of said at least one reservoir;

    a reciprocating dual-piston pump including two pistons for filling two chambers with the liquid mobile phase flowing out of said valve and pumping alternately the liquid mobile phase filled in said chambers, one end of each piston being in contact with the periphery of a rotatable cam in opposition to one end of the other piston at 180 degrees, the other end of each piston extending into each of said chambers, each of said pistons being reciprocated linearly along the contour of said cam with the rotation of said cam, thus filling said liquid mobile phase into said chambers and pumping said liquid mobile phase out of said chambers;

    an injector for injecting a specimen into the liquid mobile phase passed through said pump;

    a column for separating the specimen injected by said injector, into components;

    a detector for detecting the components of said specimen separated by said column;

    a programmer for controlling the operating time of said at least one valve;

    motor means coupled to said cam of said pump for driving said pump through successive cycles of reciprocation;

    said cam having a shape such that when the time derivative of displacement of one piston is positive over an angle range, the time derivative of displacement of the other piston is a negative fixed value over substantially the entire angle range that said one piston is positive, and when the time derivative of displacement of said one piston is negative over an angle range, the time derivative of displacement of said other piston is a positive fixed value over substantially the entire angle range that said one piston is negative.

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