Apparatus for administering intravenous drugs

• US 4,233,973 A
• Filed: 05/09/1979
• Issued: 11/18/1980
• Est. Priority Date: 05/12/1978
• Status: Expired due to Term

• Current Assignee: Vishnu S. Shukla
• Original Assignee: Vishnu S. Shukla
• Inventors: Shukla, Vishnu S.
• Primary Examiner(s): Michell, Robert W.
• Assistant Examiner(s): Wallen, T. J.
• Application Number:
  US06/037,957
• Time in Patent Office: 559 Days
• Field of Search: 128/214 R, 128/214.2, 128/214.4, 128/272.1, 128/218 M, 128/215
• US Class Current: 604/84
• CPC Class Codes: A61M 5/1409 in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems needle sets A61M5/162

Abstract

Apparatus for administering intravenously a drug supplied initially in powdery form, in particular cytotoxic drugs, said apparatus comprising a sealed container for the drug, an infusion set supplying a drip feed of intravenous liquid to the patient and also being in communication with the interior of said sealed container, and a piston-cylinder pump assembly also in communication with the interior of said container in such a manner that appropriate actuation of the pump assembly can first of all draw intravenous liquid from the infusion set into the container to dissolve the drug into solution and thereafter can feed a controlled volume of said solution from the container to the patient. The apparatus thereby provides a closed circuit for the drug which can be administered without removing from the circuit any component containing or transporting the drug. The apparatus can readily be made opaque thereby avoiding photodegradation of photosensitive drugs being administered.

Claims

1. Apparatus for administering intravenously a drug supplied in powdery form, the apparatus comprising an intravenous infusion set having a drip feed including a venipuncture member for feeding intravenous liquid into a patient'"'"'s vein, a sealed container for the powdery drug, pump means for controlling the flow of fluid to and from the sealed container, said pump means including a piston-cylinder assembly, the cylinder of which is in communication with the upper regions of the sealed container, and a tubular member extending from the lower regions of said container to communicate into the drip feed of the intravenous liquid to the patient, the arrangement being such that withdrawal of the piston in the cylinder of the pump means partially evacuates the sealed container, the removed gaseous content of said container being replaced by intravenous liquid fed under gravity from the infusion set to dissolve the powdery drug into solution, controlled return movement of the piston in the cylinder of the pump means forcing a controlled volume of solution from the sealed container through the tubular member to the infusion set whereby said solution, together with the intravenous liquid from the infusion set, is fed by the venipuncture member to the patient.

2. Apparatus as claimed in claim 1 in which the pump means comprises a medical injection syringe.

3. Apparatus as claimed in claim 2 and including a stopper of a resilient, self-sealing material sealing the container, and a rigid hollow needle one end of which is attached to the syringe, said needle extending through said stopper, the other end of the needle being located in the upper regions of said container.

4. Apparatus as claimed in claim 3 in which the tubular member includes a rigid, hollow needle extending from the lower regions of the container, through the upper regions of said container, through said stopper to the exterior of the container, and a length of flexible tubing from the upper end of said needle to the venipuncture member.

5. Apparatus as claimed in claim 4 and including a safety valve in the length of flexible tubing between the upper end of said needle and the venipuncture member to prevent air passing from the sealed container to the venipuncture member.

6. Apparatus as claimed in claim 1 in which the venipuncture member includes a flexible cannula one end of which is for location in a patient'"'"'s vein and the other end of which is adapted for attachment to both the infusion set and the tubular member extending from the lower regions of the container.

7. Apparatus as claimed in claim 6 in which the infusion set includes a further length of tubing, an extent of resilient, self-sealing material being contained within said further length of tubing, a hollow arm member being provided at the other end of the cannula to extend substantially laterally from said cannula, said further length of tubing being attached to said arm member, a rigid hollow needle attached to the end of the tubular member remote from the sealed container, said needle having a free end projecting through the material of, into the bore of, said extent of resilient, self-sealing material.

8. Apparatus as claimed in claim 7 in which a plug of a resilient self-sealing material closes the other end of the cannula, and a transparent chamber forms an extension of said other end of the cannula, the venipuncture member further comprising a rigid, hollow needle extending through the plug and through the bore of the cannula to terminate in a one end projecting just beyond the one end of the cannula, the other end of said needle being located within said transparent chamber.

9. Apparatus as claimed in claim 1 and including a safety valve in the infusion set between a source of intravenous liquid in said set and the venipuncture member.

10. Apparatus as claimed in claim 1 in which the container and at least that part of the tubular member between the container and the venipuncture member are opaque.