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Electromagnetic method for the noninvasive analysis of cell membrane physiology and pharmacology

  • US 4,240,027 A
  • Filed: 08/31/1978
  • Issued: 12/16/1980
  • Est. Priority Date: 08/31/1978
  • Status: Expired due to Term
First Claim
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1. A method for noninvasive analysis of cell membrane physiology and pharmacology by measurement of the reflection coefficient with electromagnetic energy in the high frequency band applied to cellular suspensions in order to evaluate the selective permeability thereof comprising the steps of subjecting a sample of cell suspension to two port automatic network analysis step-wise over a plurality of preselected frequencies in the high frequency band and measuring the reflection coefficient thereof for each of the plurality of preselected frequencies and calculating the complex permittivity at each of the plurality of preselected frequencies to determine contrast between the introcellular and extracellular spaces based upon the dispersion of complex permittivity.

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