Method and apparatus for measuring the ohmic contact resistance of an electrode attached to body tissue

• US 4,245,643 A
• Filed: 08/15/1979
• Issued: 01/20/1981
• Est. Priority Date: 08/15/1979
• Status: Expired due to Term

• Current Assignee: Children's Hospital & Medical Center
• Original Assignee: Children's Hospital & Medical Center
• Inventors: Benzing, George III, Iltis, Rumult
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US06/066,770
• Time in Patent Office: 524 Days
• Field of Search: 128/419 PT, 128/419 R, 128/421, 128/422, 128/695, 128/696, 128/697, 128/642
• US Class Current: 607/28
• CPC Class Codes: A61B 2018/00875 Resistance or impedance
• CPC Class Codes: A61N 1/3706 Pacemaker parameters stimulation threshold A61N1/371
• CPC Class Codes: G01R 27/14 Measuring resistance by measuring current or voltage obtained from a reference source G01R27/16, G01R27/20, G01R27/22 take precedence

Abstract

A method and apparatus are disclosed for measuring the ohmic, that is, purely d-c, resistance at the area of contact between cardiac tissue and a pacemaker electrode surgically implanted in the heart of a patient requiring a pacemaker. The contact resistance is measured by apparatus connected across the electrical circuit formed by the electrode and heart. The apparatus includes circuitry for sampling and holding the instantaneous voltage across the electrical circuit formed by the electrode and heart at the onset of a pulse generated by the pacemaker pulse generator, at which time the effect of a parallel capacitance in the electrical circuit formed by the pulse generator, electrode wire, electrode, heart, and return path through the body to the pulse generator is such that the current initially produced is determined only by the voltage and equivalent output impedance of the pulse generator, the resistance of the electrode wire, and the resistance at the area of contact between cardiac tissue and the electrode. The apparatus further includes analog signal processing circuitry for deriving the contact resistance from the instantaneous voltage based on an equivalent circuit model for the electrical circuit formed by the pacemaker and the heart taking into account the effect of the parallel capacitance at the onset of a pulse. The apparatus also includes a device for displaying the measured contact resistance. The disclosed method and apparatus are also applicable for measuring the ohmic contact resistance of an electrode attached to other body tissue.

Claims

1. A method for measuring the ohmic contact resistance of an electrode attached to body tissue, the method including the steps of:

attaching the electrode to the body tissue;

connecting a pulse generator having a given pulse amplitude and a given equivalent output impedance to the electrode, the pulse generator, electrode, and body tissue forming an electrical circuit;

generating a pulse by means of the pulse generator;

determining the instantaneous voltage across the body tissue and electrode at the onset of the pulse;

deriving the ohmic contact resistance of the electrode based on the given amplitude, the given equivalent output impedance, and the instantaneous voltage; and

displaying the ohmic contact resistance.

2. A method for measuring the ohmic contact resistance of an electrode surgically implanted in a patient'"'"'s heart, the electrode for electrically connecting a pacemaker pulse generator having a given equivalent output impedance to the heart, the pulse generator, electrode, and heart forming an electrical circuit, the pulse generator for generating discrete pulses having a given amplitude, the pulses for providing pacing signals for stimulating the heart, the method including the steps of:

generating an enabling signal in response to the leading edge of a pulse;

sampling and holding the instantaneous voltage across the electrode and heart in response to the enabling signal;

deriving the ohmic contact resistance of the electrode based on the given equivalent output impedance, the given amplitude, and the instantaneous voltage; and

displaying the ohmic contact resistance.

3. Apparatus for measuring the ohmic contact resistance of an electrode attached to body tissue, said apparatus comprising:

a pulse generator connected to said electrode, said pulse generator having a given pulse amplitude and a given equivalent output impedance, said pulse generator, electrode, and body tissue forming an electrical circuit;

a means connected across said body tissue and electrode for determining the instantaneous voltage across said body tissue and electrode at the onset of a pulse generated by said pulse generator;

analog signal processing circuitry connected to said instantaneous voltage determining means for deriving the ohmic contact resistance of said electrode based on said given amplitude, said given equivalent output impedance, and said instantaneous voltage; and

a means connected to said analog signal processing circuitry for displaying said ohmic contact resistance derived by said signal processing circuitry.

5. The apparatus in claim 3 or 4 wherein said equivalent output impedance of said pacemaker is Z₀ and said amplitude of said pulses is e_s and wherein said analog signal processing circuitry includes:

an inverting amplifier having an input and an output, said inverting amplifier input being connected by an input resistor to said sample and hold circuitry, said inverting amplifier input and output being interconnected by a feedback resistor, the ratio of said feedback resistor to said input resistor being preset to equal |Z₀ |;

a noninverting amplifier having an input and an output, said noninverting amplifier input being connected to said sample and hold circuitry;

circuitry for producing an offset in the signal at said noninverting amplifier output, said offset being preset to equal e_s ; and

a divider having two inputs and an output, said divider inputs being respectively connected to said amplifier outputs for dividing the signal at said inverting amplifier output by the signal at said noninverting amplifier output.

6. The apparatus in claim 5 wherein the electrode wire resistance is small relative to said ohmic contact resistance and said divider output is connected to said display means.

7. The apparatus in claim 5 wherein the electrode wire resistance is not small relative to said ohmic contact resistance and wherein said analog signal processing circuitry further includes:

a second noninverting amplifier having an input and an output, said noninverting amplifier input being connected to said divider output;

circuitry for producing an offset in the signal at said second noninverting amplifier output, said offset being preset to equal said electrode wire resistance, said second noninverting amplifier output being connected to said display means.

8. The apparatus in claim 6 wherein said display means is a digital voltmeter.

9. The apparatus in claim 7 wherein said display means is a digital voltmeter.

4. Apparatus for measuring the ohmic contact resistance of an electrode surgically implanted in a patient'"'"'s heart, said electrode for electrically connecting a pacemaker pulse generator having a given equivalent output impedance to said heart, said pulse generator, electrode, and heart forming an electrical circuit, said pulse generator for generating discrete pulses having a given amplitude, said pulses for providing pacing signals for stimulating said heart, said apparatus comprising:

control circuitry connected to said pulse generator and responsive to the leading edge of a pulse for generating an enabling signal;

sample and hold circuitry connected across said electrode and heart and connected to said control circuitry and responsive to said enabling signal for capturing the instantaneous voltage across said electrode and heart at the onset of said pulse;

analog signal processing circuitry connected to said sample and hold circuitry and responsive to said captured instantaneous voltage for deriving the ohmic contact resistance of said electrode based on said given equivalent output impedance, said given amplitude, and said captured instantaneous voltage; and

a means connected to said analog signal processing circuitry for displaying said ohmic contact resistance derived by said analog signal processing circuitry.