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Method and preparation for administration to the mucosa of the oral or nasal cavity

  • US 4,250,163 A
  • Filed: 12/13/1979
  • Issued: 02/10/1981
  • Est. Priority Date: 03/05/1979
  • Status: Expired due to Term
First Claim
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1. In a method for administering a medicament which comprises adhering with a polyacrylate to the mucosa of the oral cavity a pharmaceutical preparation, the improvement comprising adhering said medicament with(a) a water-swellable and mucosa-adhesive polymeric matrix comprising about 50 to about 95% by weight of a cellulose ether and about 50 to about 5% by weight of a homo- or copolymer of acrylic acid or pharmaceutically acceptable salt thereof, and(b) dispersed therein, a pharmaceutically effective amount of the medicament to be adhered to the oral mucosa,said preparation releasing continuously the medicament at a controlled rate;

  • and causing the released medicament to be absorbed through the mucosa or enterally.

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