Pyrido-[2,3-d]pyrimidine compounds
First Claim
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1. A pyrido[2,3-d]pyrimidine of formula (B) ##STR15## wherein R1 is alkyl of 1 to 6 carbon atoms or hydroxyalky of 1 to 6 carbon atoms or --CH2 (CHOH)n H where n is 1 to 5 and wherein R2, R3 and R4 are the same or different and can each represent hydrogen or alkyl having from 1 to 4 carbon atoms.
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Abstract
8-Substituted pyrido[2,3-d]pyrimidines having activity against microorganisms which utilize de novo synthesis of riboflavin.
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8 Claims
- 1. A pyrido[2,3-d]pyrimidine of formula (B) ##STR15## wherein R1 is alkyl of 1 to 6 carbon atoms or hydroxyalky of 1 to 6 carbon atoms or --CH2 (CHOH)n H where n is 1 to 5 and wherein R2, R3 and R4 are the same or different and can each represent hydrogen or alkyl having from 1 to 4 carbon atoms.
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4. 2,3,4,8-Tetrahydro-5,6-dimethyl-2,4-dioxo-8-D-ribitylpyrido[2,3-d]pyrimidine.
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5. 2,3,4,8-Tetrahydro-2,4-dioxo-8-D-ribitylpyrido[2,3-d]pyrimidine.
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6. 2,3,4,8-Tetrahydro-6,7-dimethyl-2,4-dioxo-8-D-ribitylpyrido[2,3-d]pyrimidine.
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Current AssigneeBurroughs Wellcome Co. (GlaxoSmithKline PLC)
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Original AssigneeBurroughs Wellcome and Co.
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InventorsWood, Hamish C. S., Paterson, Thomas
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Primary Examiner(s)Daus, Donald G.
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Assistant Examiner(s)Turnipseed, James H.
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Application NumberUS05/891,831Time in Patent Office1,062 DaysField of Search544/279US Class Current544/279CPC Class CodesC07D 471/04 Ortho-condensed systems
