Multilayered integral element for the chemical analysis of the blood

• US 4,255,384 A
• Filed: 08/14/1979
• Issued: 03/10/1981
• Est. Priority Date: 08/14/1978
• Status: Expired due to Term

• Current Assignee: Fuji Photo Film Co Limited (Fujifilm Holdings Corporation)
• Original Assignee: Fuji Photo Film Co Limited (Fujifilm Holdings Corporation)
• Inventors: Arai, Fuminori, Kitajima, Masao, Kondo, Asaji
• Primary Examiner(s): Richman, Barry S.
• Application Number:
  US06/066,363
• Time in Patent Office: 574 Days
• Field of Search: 422/56, 422/57, 422/58
• US Class Current: 422/428
• CPC Class Codes: G01N 33/525 Multi-layer analytical elements

Abstract

An integral multilayered element for the chemical analysis of the blood comprising a combination of a porous spreading layer, a reagent layer, and a radiation-blocking layer, said radiation-blocking layer being water-permeable and containing at least one elemental metal or an alloy thereof.

Claims

1. An integral multilayered element for the chemical analysis of the blood comprising a combination of a porous spreading layer, a reagent layer, and a radiation-blocking layer, said radiation-blocking layer being water-permeable and containing at least one elemental metal or an alloy thereof.

2. The element of claim 1, wherein said metal is selected from the group consisting of platinum, gold, silver, nickel, chromium, aluminum, zinc, tin, and cooper and alloys and mixtures thereof.

3. The element of claim 1, wherein said element comprises a porous spreading layer, a radiation-blocking layer and a reagent layer laminated in that order.

4. The element of claim 1, wherein said element comprises a support having laminated thereto in order a reagent layer, a radiation-blocking layer and a porous spreading layer.

5. The element of claim 1, wherein said element comprises a detecting layer, a radiation-blocking layer, a reagent layer and a porous spreading layer in that order.

6. The element of claim 1, wherein said element comprises a support having laminated thereto in order a detecting layer, a radiation-blocking layer, a reagent layer, and a porous spreading layer.

7. The element of claim 1, wherein said radiation-blocking layer is positioned on one surface of said porous spreading layer.

8. The element of claim 1, which further comprises a water evaporation blocking cover releasably mounted on the surface of the porous spreading layer which is opposite the surface nearest the reagent layer.

9. The element of claim 1, wherein said radiation-blocking layer is a porous metal film.

10. The element of claim 9, wherein said porous metal film is about 50 to about 1,000 A thick.

11. The element of claim 1, which further comprises a waterproof layer in contact with the surface of the porous spreading layer opposite the surface which is nearest the reagent layer.

12. The element of claim 11, which further comprises a filter layer interposed between said waterproof layer and said porous spreading layer.

13. The element of claim 1, wherein said radiation-blocking layer is a layer of a metal powder dispersed in a binder.

14. The element of claim 13, wherein said metal powder has a particle size of about 1 to 20 μ

m.

15. The element of claim 13, wherein said metal powder is an aluminum platelet about 1 to 50 μ

m² in area and about 2 μ

m or less in thickness.

16. The element of claim 13, wherein the weight ratio of said metal powder to said binder is about 100:

1 to 1;

100.