5,5-Diphenylhydantoins
First Claim
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1. A 5,5-diphenylhydantoin compound having the structural formula:
- ##STR12## wherein each R is independently selected from the group consisting of hydrogen and --CH(R1)--O--P(O)(OH)2, wherein R1 is selected from the group consisting of hydrogen and C1 -C7 straight or branched chain alkyl;
with the proviso that the R'"'"'s cannot simultaneously be hydrogen;
or the pharmaceutically acceptable acid addition or basic salts, C1 -C4 alkylhalide quaternary salts or N-oxide thereof.
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Abstract
Novel 5,5-diphenylhydantoins useful as anticonvulsants, antiepileptics and antiarrhythmics have the structural formula: ##STR1## wherein each R is hydrogen or --CH(R1)--X--P(O)(OH)2, R1 is hydrogen or C1 -C7 straight or branched chain alkyl, and X is O or S, with the proviso that both R'"'"'s cannot simultaneously be hydrogen.
59 Citations
3 Claims
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1. A 5,5-diphenylhydantoin compound having the structural formula:
- ##STR12## wherein each R is independently selected from the group consisting of hydrogen and --CH(R1)--O--P(O)(OH)2, wherein R1 is selected from the group consisting of hydrogen and C1 -C7 straight or branched chain alkyl;
with the proviso that the R'"'"'s cannot simultaneously be hydrogen;
or the pharmaceutically acceptable acid addition or basic salts, C1 -C4 alkylhalide quaternary salts or N-oxide thereof. - View Dependent Claims (2, 3)
- ##STR12## wherein each R is independently selected from the group consisting of hydrogen and --CH(R1)--O--P(O)(OH)2, wherein R1 is selected from the group consisting of hydrogen and C1 -C7 straight or branched chain alkyl;
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Current AssigneeDuPont Performance Elastomers L (Bristol-Myers Squibb Company)
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Original AssigneeInterx Research Corporation
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InventorsStella, Valentino J., Sloan, Kenneth B.
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Primary Examiner(s)Randolph, John D.
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Assistant Examiner(s)Fan, Jane T.
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Application NumberUS06/033,234Time in Patent Office713 DaysField of Search548/312, 548/112US Class Current548/112CPC Class CodesC07D 233/72 Two oxygen atoms, e.g. hyda...C07F 9/6506 having the nitrogen atoms i...
