Biodestructive material for bone fixation elements

• US 4,263,185 A
• Filed: 10/01/1979
• Issued: 04/21/1981
• Est. Priority Date: 10/01/1979
• Status: Expired due to Term

• Current Assignee: Anatoly B. Davydov, Anatoly D. Moschensky, Gely G. Pershin, Gennady I. Roitberg, Gennady L. Khromov, Gennady L. Voskresensky, Ilya A. Movshovich, Sergei I. Belykh, Valery A. Moskvitin
• Original Assignee: Anatoly B. Davydov, Anatoly D. Moschensky, Gely G. Pershin, Gennady I. Roitberg, Gennady L. Khromov, Gennady L. Voskresensky, Ilya A. Movshovich, Sergei I. Belykh, Valery A. Moskvitin
• Inventors: Belykh, Sergei I., Davydov, Anatoly B., Khromov, Gennady L., Moschensky, Anatoly D., Pershin, Gely G., Moskvitin, Valery A., Movshovich, Ilya A., Roitberg, Gennady I., Voskresensky, Gennady L.
• Primary Examiner(s): Hoke, V. P.
• Application Number:
  US06/080,296
• Time in Patent Office: 568 Days
• Field of Search: 260/8, 260/17.4, 260/42.14, 260/29.6 HN, 525/57, 525/178, 128/92 G, 128/92 C, 128/92 CA, 128/DIG. 8, 128/156, 526/264
• US Class Current: 523/115
• CPC Class Codes: A61B 17/58 for osteosynthesis, e.g. bone plates, screws , setting implements or the like A61B17/14, A61B17/16 take precedence
• CPC Class Codes: A61L 31/129 containing macromolecular fillers
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: C08L 39/06 Homopolymers or copolymers of N-vinyl-pyrrolidones

Abstract

This invention relates to medical technique and more particularly it relates to biodestructive materials used to manufacture elements for fixation of bone fragments.

Said material contains a matrix of non-toxic polymer resolvable in the body consisting of hydrophilic and hydrophobic repeat units, and a reinforcing component of non-toxic fibres or threads resolvable in the body. The matrix polymer is preferably a copolymer of methyl methacrylate and N-vinyl pyrrolidone, and the reinforcing component is preferably fibre or threads of polyamide and oxycellulose.

Said material can be used in medicine for fixation of bone fragments in fractures or injuries of bones.

Claims

1. A biodestructive material for bone fixation elements comprising from 20 to 50 percent by weight of a matrix of a non-toxic body resolvable copolymer consisting essentially of 20 to 40 percent by weight of hydrophilic monomer units and 80 to 60 percent by weight of hydrophobic monomer units, and 80 to 50 percent by weight of a reinforcing component made of a non-toxic and body resolvable threads or fibers wherein said hydrophilic monomer units are selected from the group consisting of N-vinyl pyrrolidone, hydrophobic acrylamides, vinyl caprolatam, the mono methacrylic acid ester of ethylene glycol and acrylic acid, the hydrophobic monomer units are selected from the groups consisting of hydrophobic acrylates and vinyl acetate, and the resolvable threads or fibers are selected from the group consisting of polyamide, oxy cellulose, polyvinyl alcohol and naturally-occurring non toxic resolvable fibers.

2. A material of claim 1, wherein the hydrophilic monomer units in the matrix polymer are N-vinyl pyrrolidone or acrylamide units.

3. A material of claim 1, wherein the hydrophobic monomer units of the matrix polymer are alkyl acrylate monomer units.

4. A material of claim 3 wherein the alkyl acrylate is methyl methacrylate.

5. A material of claim 1 or 2 or 3 or 4, wherein the reinforcing component comprises fibers or threads selected from the group consisting of polyamide, oxycellulose, polyvinyl alcohol and mixtures thereof.

6. A material of claim 1 wherein the matrix is a copolymer of methyl methacrylate and N-vinyl pyrrolidone, in which N-vinyl pyrrolidone monomer units comprises 25-28 percent by weight and the reinforcing component comprises polyamide fibers.