Method of and device for determining internal body structure

• US 4,263,920 A
• Filed: 03/26/1979
• Issued: 04/28/1981
• Est. Priority Date: 03/25/1978
• Status: Expired due to Term

• Current Assignee: Hermann Schomberg, Manfred Tasto
• Original Assignee: Hermann Schomberg, Manfred Tasto
• Inventors: Schomberg, Hermann, Tasto, Manfred
• Primary Examiner(s): Michell, Robert W.
• Assistant Examiner(s): Jaworski, Francis J.
• Application Number:
  US06/024,273
• Time in Patent Office: 764 Days
• Field of Search: 128/630, 128/653, 128/713, 128/734, 324/57 R, 324/62 R, 324/65 R, 364/481-482
• US Class Current: 600/547
• CPC Class Codes: A61B 5/0536 Impedance imaging, e.g. by tomography
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287

Abstract

Determining the internal structure of a body, for example, a human body, by means of an electric field which extends between individual electrodes of an electrode array which at least partly surrounds the body. Each time the value of the currents flowing through the individual electrodes is measured. From the currents electrical resistance values in individual tubes of flux generated between the electrodes are measured. By exposure of the body successively to electric fields which each have a different direction and by measurement of the resistance values then occurring, the specific resistance in individual elements of a matrix which is imagined to be stationary with respect to the body can be determined. From the given distribution of the specific resistance in the elements of the matrix, resistance values are calculated in all tubes of flux successively at least once for each field direction. For determination of a correction for the specific resistance in the elements of the matrix, the calculated resistance values are compared with the measured resistance values. The magnitude of the difference determines the magnitude of the correction.

Claims

1. A method of determining the internal structure of a body comprising the steps of:

exposing the body to an electric field which extends between individual electrodes of an electrode array which at least partially surrounds the body;

successively rotating the electric field through a plurality of different orientations with respect to the body;

measuring electric currents which flow between the individual electrodes for each of the different orientations of the electric field;

determining electrical resistance projections for individual tubes of current flux generated between the electrodes for each of the orientations of the electric field from the measurements of electrical current; and

determining the value of electrical resistance in individual elements of an imaginary matrix defined over the body by;

(a) assuming a specific distribution of resistance over the matrix elements;

(b) calculating an approximate distribution of field lines and equipotential lines within the body for each orientation of the field on the basis of the assumed distribution of resistance;

(c) calculating an approximate resistance in each tube of flux on the basis of the approximate distribution of the field lines and the assumed distribution of resistance;

(d) calculating a correction resistance distribution in each tube of flux by determination of the difference between the approximate resistance in that tube and the resistance projection determined from the measurement of the electric currents; and

(e) calculating a correction value for the specific resistance value for each element from the correction resistance distribution by interpolation.

2. A method as claimed in claim 1 wherein the approximate resistance value for each tube of flux is calculated by:

(a) subdividing each tube of flux into meshes which are bonded by equipotential lines;

(b) determining the length and width dimensions of each mesh as defined by the cross-points of field lines and equipotential lines;

(c) determining, for each mesh, an approximate resistance by interpolation between the assumed specific resistance values associated with matrix elements which at least partially coincide with that mesh; and

(d) summing the approximate resistance of individual meshes associated with the tube of flux.

3. A method as claimed in claim 2 wherein calculating the correction resistance distribution in each tube of flux comprises the steps of:

determining the difference between the measured value of a resistance projection and the calculated approximate resistance value and

determining a mesh correction which is directly porportional to the difference and to the length of the associated mesh; and

is inversely porportional to the width of the associated mesh and to the sum of the squares of the quotients of the length and the width of each mesh in the tube of flux.

4. A method as claimed in claim 1, 2, or 3 wherein the step of rotating the electric field comprises rotating the electrode array around an axis extending through the body;

the axis being directed transverse to the electric field generated between the electrodes, the position of the axis remaining unchanged with respect to each electrode during rotation.

5. A method as claimed in claim 4 wherein the electric field is produced by connecting an alternating electric voltage to one or more of the electrodes of the array.

6. A method as claimed in claim 1, 2 or 3 wherein the step of rotating the electric field comprises generating differently directed electric fields by reversing the polarity of individual electrodes in the electrode array;

the position of the electrode array remaining unchanged with respect to the body during rotation.

7. A method as claimed in claim 6 wherein the electric field is produced by connecting an alternating electric voltage to one or more of the electrodes of the array.

8. A method as claimed in claim 1, 2, or 3 wherein the electric field is produced by connecting an alternating electric voltage to one or more of the electrodes of the array.

9. A device for determining the internal structure of a body comprising:

an electrode array comprising a plurality of individual electrodes disposed to at least partially surround the body;

means for producing a potential difference between at least some of the electrodes to produce an electric field in the body;

measuring means connected to at least some of the electrodes for measuring currents flowing through individual electrodes, the measuring system functioning to measure currents flowing through individual electrodes at different orientations of the electric field with respect to the body, the currents being a measure of the electrical resistance values in tubes of flux generated between electrodes of different potential;

means for successively changing the orientation of the elelctric field with respect to the body;

first storage means for storing orientation values which are a measure of the orientation of the successive electric fields with respect to the body and for storing projections of the measured resistance values which are derived from currents measured at an associated orientation of the field;

second storage means for storing specific, assumed resistance values each of which is associated with one element of an imaginary matrix of elements defined over the body;

third storage means for the storage of further data; and

central processor means for;

determining, for each orientation, electric field and equipotential lines which divide a space determined by the matrix into meshes from the assumed resistance value and the orientation values, and for storing values which are a measure of coordinates of the meshes in the third storage means;

determining, by interpolation, an approximate mesh resistance in each mesh from the specific resistance values in the elements and the coordinates of each mesh and for storing the approximate mesh resistances in the third storage means;

calculating a resistance value between two field lines by summation of mesh resistance values which are directly proportional to the approximate mesh resistance and to the length and inversely proportional to the width of the associated mesh;

determining, from the difference between the measured resistance value and the calculated resistance value for each field direction, a correction resistance distribution for each mesh which is directly proportional to the difference and to the length of the mesh and which is inversely proportional to the width of the mesh, and for storing the correction resistance value in the third storage means;

determining, by interpolation, from the stored correction resistance values a correction for the assumed resistance value in each elements; and

adding the correction to the associated assumed resistance value and storing sums thus obtained in the second storage means.

10. A device as claimed in claim 9 wherein the electrode array is rotatable with respect to an axis which is transverse to the direction of the electric fields generated between the individual electrodes of the array and further comprising angle measuring means coupled to the electrode array for producing the orientation values.

11. A device as claimed in claim 10 further comprising a tank of insulating material having a square cross-section, the electrode array being disposed on inner walls of the tank, at least one inner wall of the tank being provided with a row of measuring electrodes which are insulated one from the other, at least one further electrode being formed on a wall opposite the row, the further electrode having dimensions parallel and perpendicular to the row of measuring electrodes which are equal to the overall dimensions of the row of electrodes.

12. A device as claimed in claim 9 further comprising a cylindrical tank of insulating material, the electrode array being formed on an inner wall of the tank, individual electrodes of the array being adjacently arranged in a ring-like array and electrically insulated one from another, the plane of the ring being directed transverse to the cylinder axis and further comprising means for selectively reversing the polarity of individual electrodes in the array.

13. A device as claimed in claim 12 wherein the electrode array comprises individual rod-shaped electrodes which are arranged in a rigid cylinder shape, the plane of the ring being directed transverse to the cylinder axis and the electrodes being displaceable with respect to the cylinder of insulating material in the direction of the axis;

and further comprising means for selectively reversing the polarity of individual electrodes.

14. A device as claimed in claim 9 wherein the electrode array comprises an elastic band adapted to be disposed against the body and adjacent electrodes comprising an elastic, electrically conductive material which enclose the body;

and further comprising switching means for reversing the polarity of individual electrodes.

15. A device as claimed in claim 9, 11, 12, 13 or 14 wherein the electrode array further comprises guard electrode elements disposed on both sides of intermediate electrodes in the array;

the guard electrodes having dimensions which correspond to those of the individual intermediate electrodes and means for maintaining at least some of the guard electrodes at the same potential as the intermediate electrodes therebetween.