Measurement of true blood velocity by an ultrasound system

• US 4,265,126 A
• Filed: 06/15/1979
• Issued: 05/05/1981
• Est. Priority Date: 06/15/1979
• Status: Expired due to Term

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Engeler, William E., Fakiris, John A., Papadofrangakis, Emmanuel
• Primary Examiner(s): Ruehl, Charles A.
• Application Number:
  US06/048,711
• Time in Patent Office: 690 Days
• Field of Search: 73/861.25, 73/602, 128/663
• US Class Current: 73/861.25
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: G01F 1/663 by measuring Doppler frequency shift
• CPC Class Codes: G01P 5/244 involving pulsed waves
• CPC Class Codes: G01S 15/8984 Measuring the velocity vector
• CPC Class Codes: G01S 7/52063 Sector scan display

Abstract

Two components of the velocity of blood or similar liquids and the true flow vector are derived by a linear transducer array cross-beam configuration. Ultrasound pulses are transmitted from the center elements and backscattered echoes are received by left and right receiver sub-arrays whose locations depend on the observation point. A duplex imaging system with a sector scanner incorporates a Doppler modality with little added complexity and provides components of flow velocity parallel to and transverse to the acoustic beam direction from which the true velocity vector is computed.

Claims

1. A steered beam ultrasound instrument for measuring two components of the flow velocity of blood and similar liquids comprising:

a linear transducer array for transmitting pulses of ultrasound with a preselected emission frequency and for generating received echo signals,

said array being comprised of a row of elements divisible into a transmitter sub-array and into left and right receiver sub-arrays that are variably located such that received center wave vectors through any observation point in the field of view subtend approximately equal angles with respect to a transmitter wave vector through the observation point,

means for exciting the elements of said transmitter sub-array to sequentially generate ultrasound pulses that propagate along a designated beam direction and insonify a sample volume through which the true flow velocity vector is being determined,

left and right receiver means for coherently demodulating echo signals generated by the respective sub-arrays with phase quadrature emission frequency references and for producing left and right focused in-phase and quadrature signals,

computation means for deriving in-phase and quadrature Doppler signals for the beam direction and for the transverse direction realized by combining four signals representing the differences of the focused left and right in-phase and quadrature signals and the sums of the focused left and right in-phase and quadrature signals,

a range gate for extracting analog samples from said Doppler signals after every pulse transmission at a time corresponding to reception of echoes backscattered from the sample volume, and

a Doppler processor for deriving from sets of said analog samples two components of flow velocity parallel to and transverse to the beam direction.

2. The ultrasound instrument of claim 1 further including means for vectorially summing the two components of velocity to realize the true flow velocity vector.

3. The ultrasound instrument of claim 2 wherein said Doppler processor is a real time digital Fast Fourier Transform processor.

4. The ultrasound instrument of claim 1 wherein said computation means for deriving Doppler signals is comprised of circuitry for producing two difference signals representing the differences of the left and right focused in-phase and quadrature signals and two sum signals representing the sums of the left and right focused in-phase and quadrature signals, and circuitry for combining said difference and sum signals to obtain two in-phase and two quadrature Doppler signals.

5. The ultrasound instrument of claim 4 wherein one of said left and right receiver means for coherently demodulating echo signals with phase quadrature references is operative to shift the phase of the references by π

in alternate ultrasound pulse repetition intervals, and wherein said computation means includes an interpolation filter at the output of the circuitry for producing two difference and two sum signals.

6. A steered beam ultrasound instrument for measuring the true flow velocity of blood and similar liquids comprising:

a linear transducer array comprised of a row of transducer elements divisible into a central transmitter sub-array and into left and right receiver sub-arrays that are variably located such that straight lines between any observation point in the field of view and the centers of said receiver sub-arrays have equal angles with respect to a straight line between the observation point and the center of said transmitter sub-array,

transmitter means for exciting the transmitter sub-array elements to sequentially generate pulses of ultrasound with a preselected emission frequency that propagate along a designated beam direction and insonify a sample volume through which the true flow velocity vector is being determined,

left and right receiver means for coherently demodulating received echo signals, generated by the elements of the respective sub-arrays, with phase quadrature emission frequency reference signals and for time delaying and summing the demodulated signals to produce focused in-phase and quadrature signals for both the left and right sub-arrays,

a Doppler signal computation circuit for deriving two difference signals representing the differences of the left and right focused in-phase and quadrature signals and two sum signals representing the sums of the left and right focused in-phase and quadrature signals, and for combining said four sum and difference signals to produce in-phase and quadrature Doppler processor input signals for the beam direction and for the transverse direction,

a range gate for extracting analog samples from said Doppler signals after every pulse transmission at a time corresponding to reception of echoes backscattered from the sample volume,

a Doppler processor embodying a complex arithmetic implementation of the Fourier Transform for deriving from sets of said analog samples two components of flow velocity parallel to and transverse to the beam direction, and

means for vectorially summing the two components of flow velocity to realize the true velocity vector.

7. The ultrasound instrument of claim 6 wherein one of said left and right receiver means for coherently demodulating echo signals with phase quadrature reference signals has provision for shifting the phase of the reference signals by π

in alternate ultrasound pulse repetition intervals, and an interpolation filter through which the two difference and two sum signals pass before being combined.

8. The ultrasound instrument of claim 6 wherein said complex Fourier Transform processor operates in real time at plural pulse transmission repetition frequencies and is a sixteen-point Fast Fourier Transform processor.

9. The ultrasound instrument of claim 8 further including display means for visually displaying true bidirectional velocity as a function of time.

10. A duplex ultrasonic imaging system having a B-scan and Doppler orientation mode of operation and a subsequent Doppler mode of operation comprising:

a common linear array of transducer elements for both modes for transmitting pulses of ultrasound with a preselected emission frequency and for generating received echo signals,

means for exciting selected elements during B-scan operation to sequentially generate ultrasound pulses that propagate along different beam directions to perform a sector scan of a region being examined,

means for coherently demodulating said echo signals using phase quadrature emission frequency references and for time delaying and summing the demodulated signals to produce a focused in-phase and a focused quadrature signal,

means for deriving a resultant signal from said focused in-phase and quadrature signals, and a B-scan display for displaying the resultant signals as a visual image of the insonified region,

said linear array during Doppler operation being divisible into a transmitter sub-array and into left and right receiver sub-arrays that are variably located such that straight lines between any observation point in the field of view and the centers of said receiver sub-arrays have equal angles with respect to a straight line between the observation point and the center of said transmitter sub-array,

means for exciting said transmitter sub-array during Doppler operation to sequentially generate ultrasound pulses that are transmitted along a chosen beam direction intersecting a sample volume through which the true velocity vector is being measured, the received echo signals being coherently demodulated and time delayed as in B-scan mode except that in alternate ultrasound pulse repetition intervals the phase of the phase quadrature references in a left or right group of receiving channels is reversed by π

, and means for generating left and right focused in-phase and quadrature signals,

computation means for deriving in-phase and quadrature Doppler signals for the beam direction and transverse direction realized by combining four signals representing the differences and sums of the four left and right focuses signals,

a range gate for extracting analog samples from said Doppler signals after every pulse transmission period at a time corresponding to reception of echoes backscattered from the sample volume,

a Doppler processor for deriving from sets of said analog samples two components of velocity parallel to and transverse to the beam direction, and

means for vectorially summing the two components to realize the time flow velocity vector.

11. The duplex system of claim 10 wherein said computation means for Doppler signals is comprised of summing circuits for producing two difference and two sum signals representing the differences and sums of the left and right focused in-phase and quadrature signals, an interpolation filter through which pass said difference and sum signals, and multipliers and summers for producing said Doppler signals from different combinations of said four difference and sum signals.

12. The duplex system of claim 11 wherein said Doppler processor is a dual channel real time digital Fast Fourier Transform processor.

13. The duplex system of claim 12 further including Doppler display means comprised of at least a strip chart recorder for presenting true bidirectional velocity as a function of time.

14. A method of measuring the true flow velocity of blood and similar liquids by use of an ultrasound system having a linear array of piezoelectric elements which are divisible into a central transmitter sub-array and left and right receiver sub-arrays comprising the steps of:

exciting said transmitter sub-array to sequentially generate pulses of ultrasound that propagate along a chosen beam direction and insonify a sample volume in the object being examined through which the true velocity vector is being determined,

locating the positions of said receiver sub-arrays such that center wave vectors through the sample volume subtend approximately equal angles with respect to a transmitter wave vector through the sample volume, and alternately after every pulse transmission detecting received echoes and generating electrical echo signals,

processing the echo signals in a left group and right group of receiving channels, each having in-phase and quadrature channels in which the echo signals are coherently demodulated using phase quadrature emission frequency reference signals and are timed delayed and summed to generate left and right focused in-phase and quadrature signals,

computing in-phase and quadrature Doppler signals for the beam direction and for the transverse direction from combinations of the four left and right focused signals,

gating said Doppler signals for a short interval after every pulse transmission to extract two pairs of analog samples representing echoes backscattered from the sample volume,

analyzing sets of said pairs of analog samples with a Doppler processor to realize two components of velocity parallel to and transverse to the beam direction, and

vectorially summing the two components to realize the true flow velocity vector.

15. The method of claim 14 wherein the step of processing echo signals in left and right groups of receiving channels which are demodulated using phase quadrature reference signals comprises reversing the phase of the reference signals in one group of channels by π

in alternate ultrasound pulse repetition intervals.

16. The method of claim 15 wherein the step of computing Doppler signals comprises producing two difference signals representing the differences of the left and right focused in-phase signals and left and right focused quadrature signals, two sum signals representing the sums of the left and right focused in-phase signals and left and right focused quadrature signals, and producing the four Doppler signals by different combinations of said difference and sum signals.

17. A method of measuring the transverse component of the flow velocity of blood and similar liquids at right angles to an acoustic beam direction by use of an ultrasound system having a linear array of piezoelectric elements which are divisible into a central transmitter sub-array and left and right receiver sub-arrays, the transverse component to be vectorially summed with a component parallel to the beam direction to realize the true velocity vector, comprising the steps of:

exciting said transmitter sub-array to sequentially generate pulses of ultrasound that propagate along a chosen beam direction and insonify a sample volume in the object being examined through which the true velocity vector is being determined,

locating the positions of said receiver sub-arrays such that center wave vectors through the sample volume subtend approximately equal angles with respect to a transmitter wave vector through the sample volume, and alternately after every pulse transmission detecting received echoes and generating electrical echo signals,

processing the echo signals in a left group and right group of receiving channels, each having in-phase and quadrature channels in which the echo signals are coherently demodulated using phase quadrature emission frequency reference signals and are time delayed and summed to generate left and right focused in-phase and quadrature signals,

computing in-phase and quadrature Doppler signals for the transverse direction from combinations of the four left and right focused signals,

gating said Doppler signals for a short interval after every pulse transmission to extract a pair of analog samples representing echoes backscattered from the sample volume, and

analyzing sets of said pairs of analog samples with a Doppler processor to realize the component of velocity transverse to the beam direction.