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Cystic fibrosis detection method

  • US 4,273,869 A
  • Filed: 04/16/1979
  • Issued: 06/16/1981
  • Est. Priority Date: 04/16/1979
  • Status: Expired due to Term
First Claim
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1. A method for the diagnosis of cystic fibrosis, the detection of non-symptomatic carriers of the disease and the identification of non-affected persons, which method comprises:

  • (A) obtaining a sample of cells possessing mitochondria from a human subject,(B) preparing a homogenate of the cells,(C) performing an assay on the homogenate of cells which measures the mitochondrial activity of the cells, and(D) evaluating the assay by comparing the measurements with standards established as a result of similar assays of other subjects of known cystic fibrosis condition.

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