Variable stop syringe

• US 4,278,086 A
• Filed: 01/28/1980
• Issued: 07/14/1981
• Est. Priority Date: 01/28/1980
• Status: Expired due to Term

• Current Assignee: Coulter Electronics, Inc. (Danaher Corporation)
• Original Assignee: Coulter Electronics, Inc. (Danaher Corporation)
• Inventors: Saltz, Ivan K., Hodgins, Bruce J., Ginsberg, Guenter
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US06/115,624
• Time in Patent Office: 533 Days
• Field of Search: 128/215, 128/218 R, 128/218 A, 128/214 R, 128/214 E, 128/214 F, 128/224, 128/DIG. 1, 128/DIG. 12, 128/213, 222/129, 222/132, 222/136, 222/137, 222/145
• US Class Current: 222/137
• CPC Class Codes: B01L 3/0224 having mechanical means to set stroke length, e.g. movable stops B01L3/0231, B01L3/0234 take precedence
• CPC Class Codes: G01F 11/023 with provision for varying the stroke of the piston

Abstract

A variable stop syringe for automatically selecting, aspirating and dispensing one of a desired plurality of fluid volumes. The variable syringe includes a plurality of stops in an array each of which defines a particular fluid volume. The array selectively is moved to position the desired stop in the fully aspirated position of the syringe plunger. The stop positions are coded and automatically may be read to select the desired syringe stop for the particular volume of fluid desired to be aspirated and dispensed. The completely dispensed and the fully aspirated positions of the plunger, as well as the speed of the plunger operation, may be monitored to ensure that the plunger is operating properly.

Claims

1. A method of aspirating and dispensing one of a plurality of predetermined fluid volumes from a fluid supply comprising:

selecting one of the fluid volumes;

moving a plunger stop corresponding to said selected fluid volume into a fully aspirated position;

driving a syringe plunger coupled to the fluid supply from a rest or fully dispensed position to the fully aspirated position defined by said plunger stop to aspirate said selected fluid volume; and

driving said plunger from the fully aspirated position to said fully dispensed position to dispense said selected fluid volume.

2. A method as claimed in claim 1 including:

mounting a plurality of plunger stops in an array, with one stop corresponding to each predetermined fluid volume; and

rotating said array to align the plunger stop corresponding to the selected fluid volume in said fully aspirated position.

3. A method as claimed in claim 2 including:

coding each of said plunger stop positions with an individual code; and

reading said coding as said array is rotated to select the correct plunger stop.

4. A method as claimed in claim 1 including:

sensing when said plunger is in said fully dispensed and said fully aspirated positions to ensure that said plunger has aspirated and dispensed the selected fluid volume.

5. A method as claimed in claim 4 including:

timing the elapsed time between sensing the plunger in one position and sensing the plunger in the opposite position to ensure said plunger is operating properly.

6. A method as claimed in claim 1 including:

sensing the speed of said plunger as it is driven between said positions to ensure said plunger is operating properly.

7. An apparatus adapted to selectively aspirate and dispense one of a plurality of predetermined fluid volumes when coupled to a fluid supply comprising:

means for selecting one of the fluid volumes;

plunger stop means;

means for moving said plunger stop means into a fully aspirated position corresponding to said selected fluid volume;

syringe plunger means;

means for driving said syringe plunger means from a rest or fully dispensed position to a fully aspirated position defined by said plunger stop means; and

means for driving said syringe plunger means from the fully aspirated position to said fully dispensed position.

8. An apparatus as claimed in claim 7 including:

means for sensing the speed of said plunger means as it is driven between said positions to ensure said plunger means are operating properly.

9. An apparatus as claimed in claim 7 including:

means for sensing when said plunger means are in said fully dispensed position; and

means for sensing when said plunger means are in said fully aspirated position to ensure that said plunger means have reached each position.

10. An apparatus as claimed in claim 9 including:

means for timing the elapsed time between sensing said plunger means in one position and sensing said plunger means in the opposite position to ensure said plunger means are operating properly.

11. An apparatus as claimed in claim 9 including:

said aspirated position sensing means include actuation means carried by said syringe plunger means actuated by contact with said plunger stop means for indicating when said plunger means are in said fully aspirated position; and

said dispensed position sensing means include actuation means actuated by said syringe plunger means reaching said dispensed position.

12. An apparatus as claimed in claim 11 including:

said aspirated position actuation means include a reciprocable button and a switch which is actuated by said button being displaced by contact with said plunger stop means; and

said dispensed position actuation means include a switch which is actuated by tab means carried by said plunger means.

13. An apparatus as claimed in claim 7 including:

said plunger stop means include a plurality of plunger stops mounted in an annular array, with one stop corresponding to each predetermined fluid volume; and

said moving means include means for rotating said array to align the plunger stop corresponding to the selected fluid volume in said fully aspirated position.

14. An apparatus as claimed in claim 13 including:

said plunger stops are removably mounted in an annular array on a carousel.

15. An apparatus as claimed in claim 13 including:

individual code means coding each of said plunger stop positions; and

means for reading said coding as said array is rotated to select the correct plunger stop.

16. An apparatus as claimed in claim 15 including:

said code means include a code disc fixedly mounted for rotation with said array; and

said reading means include a non-rotating optical reader which reads the angular position of said code disc.

17. An apparatus as claimed in claim 15 including:

means for sensing when said plunger means are in said fully dispensed position; and

means for sensing when said plunger means are in said fully aspirated position to ensure that said plunger means have reached each position.

18. An apparatus as claimed in claim 17 including

said aspirated position sensing means include actuation means carried by said syringe plunger means actuated by contact with said plunger stop for indicating when said plunger means are in said fully aspirated position;

and

said dispensed position sensing means include actuation means actuated by said syringe plunger means reaching said dispensed position.

19. An apparatus as claimed in claim 18 including:

said aspirated position actuation means include a reciprocable button and a switch which is actuated by said button being displaced by contact with said plunger stop; and

said dispensed position actuation means include a switch which is actuated by tab means carried by said plunger means.