Surgical cement composition

• US 4,288,355 A
• Filed: 05/22/1978
• Issued: 09/08/1981
• Est. Priority Date: 05/22/1978
• Status: Expired due to Term

• Current Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Original Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Inventors: Randklev, Ronald M., Anderson, Harvey L.
• Primary Examiner(s): Michl, Paul R.
• Application Number:
  US05/908,576
• Time in Patent Office: 1,205 Days
• Field of Search: 260/29.6 M, 260/42.55, 260/29.6 H
• US Class Current: 523/116
• CPC Class Codes: A61K 6/30 Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
• CPC Class Codes: A61K 6/54 Filling; Sealing
• CPC Class Codes: A61K 6/887 Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61K 6/889 Polycarboxylate cements; Glass ionomer cements
• CPC Class Codes: A61L 27/446 with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
• CPC Class Codes: A61L 27/50 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: C08L 33/00 Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
• CPC Class Codes: C08L 33/02 Homopolymers or copolymers of acids; Metal or ammonium salts thereof
• CPC Class Codes: Y10S 524/906 Multipackage compositions

Abstract

A surgical cement comprised of a concentrated non-gelling aqueous solution of a polycarboxylic acid and an aqueous suspension of metal oxide powder which when mixed together form a plastic mass which is formable into the desired shape before it hardens. The surgical cement has particular utility for dental applications.

Claims

1. A process for the preparation of a surgical cement which comprises forming a mixture of an aqueous suspension of metal oxide powder, said powder being about 30 to 60 percent by volume of said suspension, and an aqueous solution of polycarboxylic acid, said acid being about 55 to about 80 percent by weight of said solution, and wherein the weight ratio of said suspension of metal oxide powder to said aqueous polycarboxylic acid is 0.5/1 to 8/1.

2. A process in accordance with claim 1 wherein said metal oxide powder comprises zinc oxide.

3. A process in accordance with claim 1 wherein the metal oxide powder comprises polyvalent-cation-containing glass.

4. A process in accordance with claim 1, wherein said polycarboxylic acid is selected from the group consisting of polyacrylic acid, polymethacrylic acid, polymers derived from unsaturated alpha, beta-dicarboxylic acids, and copolymers of acrylic acid, methacrylic acid and unsaturated alpha, beta-dicarboxylic acids.

5. A process in accordance with claim 1, wherein said polycarboxylic acid comprises polyacrylic acid.

6. A process in accordance with claim 5 wherein said polyacrylic acid has a molecular weight of about 2000 to about 20,000.

7. A process in accordance with claim 1 wherein said polycarboxylic acid comprises a blend of a first polyacrylic acid having molecular weight of about 2,000 to about 20,000 and a second polyacrylic acid having a molecular weight greater than about 20,000 and wherein said first acid is present in an amount greater than said second acid.

8. A process in accordance with claim 1 wherein said aqueous solution of polycarboxylic acid also contains a thickener.

9. A process in accordance with claim 1 wherein said aqueous solution of polycarboxylic and said suspension of metal oxide powder are in paste form and are dispensed from a syringe.

10. A surgical cement pack comprising (a) a first paste consisting essentially of an aqueous solution of polycarboxylic acid, said acid being about 55 to 80 percent by weight of said solution, and (b) a second paste consisting essentially of an aqueous suspension of metal oxide powder, said powder being about 30 to 60 percent by volume of said suspension;

said pack having means to prevent premature reaction between said first and second pastes;

whereby when said second paste is mixed with said first paste, in a weight ratio of about 0.5/1 to 8/1, a plastic mass is formed which rapidly hardens as a surgical cement but which remains plastic for a time sufficient to permit forming thereof into the desired shape.