Magnetic attraction transfer devices for use in solid phase radioimmunoassays and in other assay methods
First Claim
1. A device for use in solid phase immumoassays, for simultaneously transferring a plurality of antigen-antibody absorbent units from one location to another, comprising a transfer element in combination with a tray of non-magnetic material having a plurality of spaced receptacles therein for containing an appropriate liquid and for containing units each comprising a core of ferromagnetic material, each said core being covered with at least one coating for preventing chemical interactions between said core and aqueous chemical solutions and for absorbing antigens or antibodies on the outer surface thereof, said transfer element having a first portion of ferromagnetic material overlying said spaced receptacles in a transfer condition of said element, and said element having a second portion of non-magnetic material overlying spaces between said receptacles when in said transfer condition, and one of said ferromagnetic core and transfer device materials having magnetic properties to effect a magnetic attraction between said units and said transfer device, whereby said units are removable from said receptacles by magnetic attraction while being maintained in spaced apart relationship by said non-magnetic material during said transfer condition.
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Accused Products
Abstract
A device for transferring, by magnetic attraction, antigen-antibody adsorbent materials from one reaction mixture to another, and to facilitate an efficient rinsing of these materials, and for transferring adsorbent materials used in other assay methods.
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Citations
12 Claims
- 1. A device for use in solid phase immumoassays, for simultaneously transferring a plurality of antigen-antibody absorbent units from one location to another, comprising a transfer element in combination with a tray of non-magnetic material having a plurality of spaced receptacles therein for containing an appropriate liquid and for containing units each comprising a core of ferromagnetic material, each said core being covered with at least one coating for preventing chemical interactions between said core and aqueous chemical solutions and for absorbing antigens or antibodies on the outer surface thereof, said transfer element having a first portion of ferromagnetic material overlying said spaced receptacles in a transfer condition of said element, and said element having a second portion of non-magnetic material overlying spaces between said receptacles when in said transfer condition, and one of said ferromagnetic core and transfer device materials having magnetic properties to effect a magnetic attraction between said units and said transfer device, whereby said units are removable from said receptacles by magnetic attraction while being maintained in spaced apart relationship by said non-magnetic material during said transfer condition.
Specification