Cardiovascular grafts

• US 4,300,244 A
• Filed: 09/19/1979
• Issued: 11/17/1981
• Est. Priority Date: 09/19/1979
• Status: Expired due to Term

• Current Assignee: Carbomedics Inc. (Snia SpA)
• Original Assignee: Carbomedics Inc. (Snia SpA)
• Inventors: Bokros, Jack C.
• Primary Examiner(s): Bashore, S. Leon
• Assistant Examiner(s): Lander, Ferris H.
• Application Number:
  US06/077,047
• Time in Patent Office: 790 Days
• Field of Search: 3/1, 3/1.4, 128/334 R, 128/334 C, 128/335, 128/335.5
• US Class Current: 623/1.13
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable

Abstract

Springs are used to form cardiovascular grafts.

A tightly wound spring coated with carbon while in a stretched position will have a biocompatible interior surface which provides an unobstructed passageway for blood. Fabric sleeves may be employed around springs to improve the fluid integrity of the interior surfaces.

Springs may also be used to join blood vessel segments by puncturing one segment of the blood vessel with a first end of a spring, coiling the spring therearound, puncturing a second segment of the blood vessel with a second end of the spring and coiling the spring therearound.

Claims

1. A vascular prosthesis for implantation in a living body comprising:

a tubular configuration of organopolymeric fabric;

dense, isotropic carbon coating along at least the interior surface of said tubular configuration; and

a biocompatible wire in the form of a helical spring of uniform spring diameter disposed inside said tubular configuration and having an outside spring diameter such that said spring is in surface contact with said carbon coated interior of said tubular configuration;

said spring having a pitch not greater than twice the diameter of said wire;

whereby a blood compatible surface is defined on the interior of said prosthesis where said blood compatible surface consists of at least 50% exposed surface of said spring and the remainder of said blood compatible surface consists of portions of said interior surface of said tubular configuration.

2. A vascular prosthesis according to claim 1 in which a generally cylindrical passageway is provided for blood which is free from obstruction so that blood interfaces with said prosthesis only at said blood compatible surface.

3. A cardiovascular prosthesis according to claim 1 where said wire is metal.

4. A cardiovascular prosthesis according to claim 1 wherein said wire is polymer.

5. A cardiovascular prosthesis according to claim 1 where said wire comprises a metal core surrounded by a polymer coating.

6. A cardiovascular prosthesis according to claim 1 where said carbon coating on said organopolymeric fabric has a thickness of between about 0.1 and about 0.7 microns a B.A.F. of about 1.3 or less and a density of between about 1.6 gm/cc and about 2.0 gm/cc.

7. A cardiovascular graft according to claim 1 where the pitch of said spring is equal to the diameter of said wire.

8. A vascular prosthesis according to claim 1 wherein said fabric is an array of fibers.

9. A vascular prosthesis according to claim 1 wherein said fabric is a porous polymeric material.

10. A method for grafting a first segment with a second segment of a small blood vessel comprising:

cuffing back a first and a second end of a tubular configuration of organopolymeric fabric and dense isotropic carbon coating along an interior surface of said tubular configuration, where said tubular configuration is disposed around a helical spring which is biocompatible with blood and vascular tissue and which has a first terminus and a second terminus bent outward from an axis of said helix,

puncturing the first segment of the blood vessel with said first terminus from the inside to the outside of the blood vessel,

rotating said spring about its axis in a first direction a plurality of turns thereby winding said spring around the first segment of the blood vessel;

puncturing the second segment with said second terminus from the inside to the outside of the blood vessel;

rotating said spring around its axis in a second direction a plurality of turns thereby winding said spring around the second segment until severed coils are wound around the second segment while several coils remain wound around the first segment; and

uncuffing said tubular configuration so that said tubular configuration extends over the junctions of said spring and the first and second segments whereby the first segment and the second segment are joined together to form a unitary blood conduit.

11. A method for grafting a first segment with a second segment of a small blood vessel according to claim 10 where said spring is coated with carbon.

12. A method according to claim 10 wherein said tubular configuration is an array of fibers.

13. A method according to claim 10 wherein said tubular configuration is formed from a porous polymeric material.