Method for iontophoretic treatment

• US 4,301,794 A
• Filed: 10/18/1978
• Issued: 11/24/1981
• Est. Priority Date: 10/18/1978
• Status: Expired due to Term

• Current Assignee: Robert Tapper
• Original Assignee: Robert Tapper
• Inventors: Tapper, Robert
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US05/952,341
• Time in Patent Office: 1,133 Days
• Field of Search: 128/172.1, 128/419 R, 128/419 S, 128/420 R, 128/421, 128/422, 128/423 R, 128/803, 128/207.21
• US Class Current: 604/20
• CPC Class Codes: A61N 1/0428 Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
• CPC Class Codes: A61N 1/0432 Anode and cathode
• CPC Class Codes: A61N 1/18 Applying electric currents by contact electrodes
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428

Abstract

A method and apparatus for applying iontophoretic treatment to a living body is provided by which a unidirectional treatment current is periodically interrupted by a relatively short pulse of current in the opposite direction in order to prevent the formation of undesirable vesicles and bulla in the skin being treated. The apparatus and method are arranged to impose the treatment current gradually at the beginning of each treatment.

Claims

1. A method of minimizing vesicle formation while applying iontophoretic treatment to a living body, said method including the steps of:

conducting direct current through the skin of said body in a first direction from a first electrode to a second electrode on said skin;

intermittently reversing the polarity of said electrodes to cause direct current to flow in a second direction opposite said first direction; and

controlling the flow of said current in said first and second directions so that the energy applied in said first direction exceeds the energy applied in said second direction by a ratio of between about 2;

1 and 7;

1.

2. A method as set forth in claim 1 wherein said energy applied in said first direction exceeds said energy applied in said second direction by a ratio of about 2.3 to 1.

3. A method as set forth in claim 1 further including the step of gradually increasing said current in said first direction to a treatment level at the beginning of each treatment period.

4. A method as set forth in claim 3 wherein said gradual increase of said current occurs over a period of about two seconds.

5. A method as set forth in claim 1, wherein in the step of intermittently reversing, the current flows in the second direction for a duration of about 10 μ

sec.

6. A method as set forth in claim 5, wherein in the step of intermittently reversing, the time period between successive reversals of the direction of current is at least 35 μ

sec.