Blood oxygen analyzer
First Claim
1. Apparatus for determining the oxygen exchange characteristics of hemoglobin without necessity of sample pretreatments or critical transfer requirements, comprising:
- a light-transmissive vessel for receiving a partial filling of a physiologically balanced solution a minor part of which is a blood sample,means for passing gas through said solution for changing the oxygen in contact with the solution,means for introducing light to the solution in said vessel, andmeans for spectrophotometrically evaluating the change of oxygen saturation of the blood in said solution as a function of the oxygen tension of the solution.
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Abstract
A method and system for measuring the oxygen carrying capacity of normal and abnormal hemoglobins and red cells under controlled pH, ionic strength, temperature and gas conditions is described. A blood sample and a physiologically balanced medium are placed in a cuvette and means are associated therewith for measuring the fractional saturation of the sample and the partial pressure of the oxygen (sometimes referred to as the oxygen tension) and provide output signals to an X-Y plotter for continuous recording. Preferably, means for maintaining the temperature of the medium and the blood sample is provided.
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Citations
19 Claims
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1. Apparatus for determining the oxygen exchange characteristics of hemoglobin without necessity of sample pretreatments or critical transfer requirements, comprising:
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a light-transmissive vessel for receiving a partial filling of a physiologically balanced solution a minor part of which is a blood sample, means for passing gas through said solution for changing the oxygen in contact with the solution, means for introducing light to the solution in said vessel, and means for spectrophotometrically evaluating the change of oxygen saturation of the blood in said solution as a function of the oxygen tension of the solution. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. The method of determining the oxygen exchange characteristics of hemoglobin comprising,
preparing a physiologically balanced solution including a minute blood sample, introducing light into said solution, introducing to the solution a gas which contrasts, in respect to presence or absence of oxygen therein, with the blood sample in the solution, for changing the oxygen concentration in said sample, and spectrophotometrically measuring the change in the light absorption characteristics and simultaneously measuring the change in partial pressure of the oxygen to which the solution is subjected.
Specification