Method for measuring the velocity of a perturbed jetting fluid in an electrostatic particle sorting system

• US 4,318,482 A
• Filed: 08/20/1979
• Issued: 03/09/1982
• Est. Priority Date: 08/20/1979
• Status: Expired due to Term

• Current Assignee: Ortho Diagnostics, Inc. (The Carlyle Group LP (Corporate Private Equity))
• Original Assignee: Ortho Diagnostics, Inc. (The Carlyle Group LP (Corporate Private Equity))
• Inventors: Barry, Donald E., Lombardo, Igino
• Primary Examiner(s): Rolla, Joseph J.
• Application Number:
  US06/068,235
• Time in Patent Office: 932 Days
• Field of Search: 209/3.1-3.3, 209/571, 209/579, 209/906, 209/127 R, 356/39, 356/72, 356/73, 356/335, 356/338, 250/222 R, 250/222 PC, 361/226, 364/413, 346/75
• US Class Current: 209/3.1
• CPC Class Codes: G01N 15/1404 Handling flow, e.g. hydrodynamic focusing
• CPC Class Codes: G01N 15/149 specially adapted for sorting particles, e.g. by their size or optical properties
• CPC Class Codes: G01N 2015/1406 Control of droplet point
• CPC Class Codes: Y10S 209/906 Pneumatic or liquid stream feeding item

Abstract

A method for the measurement of fluid velocity and fluid flow rate is described which may be applied to a system in which fluid is caused to exit through an orifice to form a free jet. Optical as well as fluidic properties of the jetting fluids are used to determine the mean velocity of the jet between its point of exit from the orifice and at least a preselected detection point. From the mean velocity determination, the fluid flow rate may also be determined. A marker signal perturbation is applied to the jetting fluid at the orifice, and is detected downstream at a stream sensing point which is located a preselected distance from that orifice.

Claims

1. An electrostatic particle sorting system comprising:

(a) flow means for establishing the flow of a continuous particle containing stream;

(b) perturbation means for perturbing said stream with at least a preselected frequency and amplitude to cause said stream to form a breakpoint at which said stream becomes a series of discrete droplets;

(c) stream surface sensing means for sensing at least the light scatter characteristic of said stream at a stream sensing point disposed above said breakpoint and at a preselected distance from said perturbation means; and

for producing a surface character output signal which is proportional thereto;

(d) marker signal means for selectively varying the perturbation caused by said perturbation means to create a marker signal in said stream; and

(e) marker signal detection means for monitoring said surface character output signal to detect the arrival of said marker signal at said stream sensing point.

2. The invention of claim 1 wherein said stream surface sensing means for sensing at least the light scatter character of said stream further comprises a light extinction means for sensing the light extinction character of said stream at said stream sensing point.

3. The invention of claim 1 wherein said system further comprises time delay detection means for determining the time delay between the creation of said marker signal and its said arrival at said stream sensing point.

4. The invention of claim 3 wherein said system further comprises a reference flow setting and an error signal generator means for producing an error signal proportional to differences between said reference flow setting and said time delay.

5. The invention of claim 4 wherein said flow means further comprises a proportional fluid flow rate driver responsive to said error signal for altering the flow rate of said continuous particle containing stream.

6. The invention of claim 1 wherein said perturbation means comprises a transducer and an oscillator for driving said transducer at a preselected amplitude and frequency.

7. The invention of claim 6 wherein said marker signal means comprises means for periodically modulating said amplitude.

8. The invention of claim 6 wherein said marker signal means comprises means for periodically modulating said frequency.

9. An electrostatic particle sorting method comprising the steps of:

(a) establishing the flow of a continuous particle containing stream;

(b) perturbing said stream with at least a preselected frequency and amplitude at a perturbation point defined therealong to cause said stream to form a breakpoint at which said stream becomes a series of discrete droplets;

(c) sensing at least the light scatter character of said stream at a stream sensing point disposed above said breakpoint and at a preselected distance from said perturbation point, and generating a surface character output signal which is proportional to said light scatter character of said stream at said point;

(d) selectively varying the perturbation caused at said perturbation point to create a marker signal in said stream; and

(e) monitoring said surface character output signal to detect the arrival of said marker signal at said stream sensing point.

10. The invention of claim 9 wherein said step of perturbing said stream with a preselected frequency and amplitude further comprises the step of selectively modulating said amplitude of perturbation to produce said marker signal.

11. The invention of claim 9 wherein said step of perturbing said stream further comprises the step of selectively modulating said frequency perturbation of said steam to produce said marker signal.

12. The method of claim 9 wherein said step of sensing at least the light scatter character of said stream further comprises the step of sensing at least the light extinction character of said stream.

13. The invention of claim 9 wherein said method further comprises the step of detecting the time delay between the creation of said marker signal at said perturbation point and its arrival at said stream sensing point.

14. The invention of claim 13 wherein said method further comprises the step of generating a reference flow setting and comparing that reference flow setting with said time delay to generate an error signal proportional to the differences between said reference flow setting and said time delay.

15. The invention of claim 14 wherein said method further comprises the step of altering the fluid flow rate of said continuous particle containing stream in response to said error signal.