Apparatus and method for controlling the application of therapeutic direct current to living tissue

• US 4,323,073 A
• Filed: 08/21/1979
• Issued: 04/06/1982
• Est. Priority Date: 09/11/1978
• Status: Expired due to Term

• Current Assignee: Halium Research Corporation
• Original Assignee: COS Electronics Corporation
• Inventors: Ferris, Harold
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US06/068,431
• Time in Patent Office: 959 Days
• Field of Search: 128/419 R, 128/421, 128/422, 128/420 R, 128/420 A, 128/423 R, 128/803
• US Class Current: 607/46
• CPC Class Codes: A61N 1/36021 for treatment of pain

Abstract

Apparatus and a method for applying current of a particular form to bulk resistance means such a living tissue. The applied current is D.C. at a level so low as to generate voltage gradients within the bulk resistance such as to be substantially under nerve or muscle stimulation potential. Apparatus is provided to increase the current level at a first predetermined rate to a first level for a first period of time, to lower it to a second level for a longer period of time, then to lower it to zero at a second predetermined rate. When applied to painful living tissue substantial reduction or elimination of pain and inflamation has been found to occur.

Claims

1. Apparatus for controlling the application of therapeutic direct current to living tissue comprising:

(a) means for increasing the amplitude of an applied direct current passing through the tissue from an insignificant level to a first predetermined higher level at a first controlled rate,

(b) means for changing the current level passing through the tissue to a second predetermined lower level and maintaining it for a predetermined controlled time period following attainment of the first predetermined current level, and

(c) means for decreasing the current level passing through the tissue to an insignificant level at a second controlled rate following the controlled time period,

the current levels being such as to generate voltage gradients in the tissue which are less than nerve stimulation voltage gradients.

2. Apparatus as defined in claim 1, in which the means for changing the current level includes means for controlling the second predetermined level so as to provide a voltage gradient in the tissue up to about 50 millivolts per centimeter.

3. Apparatus as defined in claim 2 in which the first predetermined current level is higher than the second predetermined current level, including further means for maintaining the first current level for a preliminary controlled time period.

4. Apparatus as defined in claim 3, in which said first predetermined level of current is about 5 milliamperes and the second predetermined level of current is about 21/2 milliamperes.

5. Apparatus as defined in claim 4, in which the preliminary controlled time period is about 5 seconds, and the predetermined controlled time period is between about 20 and 30 seconds.

6. Apparatus as defined in claim 4 or 5, in which said first controlled rate is about 5 milliamperes per second.

7. Apparatus as defined in claim 1, 2 or 5, further including electrode means for applying said current to said tissue through a broad surface contact therewith and having means for retaining conductive fluid material between the electrode means and the tissue.

8. Apparatus as defined in claim 1, 2 or 5, further including electrode means for applying said current to said tissue through a broad surface contact therewith and having means for retaining a saline water solution between the electrode and the tissue.

9. Apparatus as defined in claim 1, in which the means for changing the current level includes means for controlling the second predetermined level so as to provide a voltage gradient in the tissue of approximately 10 millivolts per centimeter.

10. Apparatus as defined in claim 1 in which the amplitude of first predetermined current level provides a voltage gradient in the tissue of about 20 millivolts per centimeter.

11. Apparatus as defined in claim 3 or 10 in which said first controlled rate is about 20 milliamperes per second.

12. Apparatus as defined in claim 3 or 10, in which said tissue includes a capacitive component, the apparatus further including means for controlling said rates so as to be slower than a predetermined rate whereby a derivative voltage is produced in said tissue by said capacitive component when said current is applied, which derivative voltage is less than nerve stimulation voltage and which is less than standing potential across muscle membrane.

13. Apparatus as defined in claim 1, in which the current levels are such as to generate voltage gradients in the tissue which are less than muscle membrane exciting voltage gradients.

14. A method of controlling direct current applied to living tissue comprising:

(a) applying a direct current source to living tissue,

(b) increasing the amplitude of the direct current from an insignificant level to a first predetermined level at a first controlled rate,

(c) maintaining the first predetermined current level for a first period of time, and

(d) decreasing the current at a second controlled rate to an insignificant level at a second controlled rate following the first period of time,

the current which is applied being predetermined to generate voltage gradients in living tissue which are less than nerve stimulation voltage gradients.

15. A method as defined in claim 14 including raising the current to said first predetermined current level to cause a voltage gradient in the tissue of less than 50 millivolts per centimeter.

16. A method as defined in claim 14 including raising the current to said first predetermined current level to cause a voltage gradient in the tissue of approximately 20 millivolts per centimeter.

17. A method as defined in claim 14 including the step of decreasing the current level from the first current level to a second predetermined current level for a second period of time prior to said step of decreasing the current to said insignificant level.

18. A method as defined in claim 17 including raising the current to said first predetermined current level to cause a voltage gradient in the tissue of the order to 20 millivolts per centimeter, and reducing the current to said second predetermined current level to cause a voltage gradient in the tissue of about 10 millivolts per centimeter.

19. The method as defined in claim 17 in which the first period of time is in the range of about 5-10 seconds, and the second period of time is in the range of about 10-60 seconds.

20. A method as defined in claim 19 in which the first controlled rate is about 5 milliamperes per second.

21. A method as defined in claim 17, 18 or 19 in which the first predetermined current level is about 5 milliamperes and the second predetermined current level is about 2 milliamperes.

22. A method as defined in claim 17 including raising the current to said predetermined current levels to cause voltage gradients in living tissue which are below the standing voltage gradient across muscle membrane.

23. A method as defined in claim 17 in which said tissue includes a capacitive component, said method including controlling said rate whereby a derivative voltage is produced in said bulk resistance means by said capacitive component when said current is applied which is less than nerve stimulation voltage and which is less than the standing voltage gradient across muscle membrane.