Patient data controlled respiration system

• US 4,326,513 A
• Filed: 06/30/1980
• Issued: 04/27/1982
• Est. Priority Date: 07/03/1979
• Status: Expired due to Term

• Current Assignee: Dragerwerk AG
• Original Assignee: Dragerwerk AG
• Inventors: Heim, Ulrich, Schulz, Volker, Kunke, Stefan
• Primary Examiner(s): Recla, Henry J.
• Application Number:
  US06/164,573
• Time in Patent Office: 666 Days
• Field of Search: 128/204.21, 128/204.22, 128/204.23, 128/203.14, 128/671
• US Class Current: 128/203.14
• CPC Class Codes: A61M 16/00 Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes stimulating the respiratory movement by mechanical, pneumatic or electrical means, iron lungs combined with gas breathing means A61H31/00
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)

Abstract

A respiration system and method for minimizing the oxygen concentration of inspiration gas supplied to a patient while maintaining a desired arterial oxygen partial pressure in the patient comprising a regulator for changing the oxygen concentration of inspiration gas supplied to a respirator according to a desired nominal value therefor and a sensed value therefor taken from the patient, a control device for adjusting parameters of the breathing gas in the respirator supplied to the patient while maintaining the desired arterial oxygen partial pressure, and a minimizer connected to the control device for changing a direction of the adjustment when the oxygen concentration in the inspiration gas cannot be maintained within a range between a first sensed instantaneous value for the oxygen concentration in the inspiration gas and a lower limit set for that value.

Claims

1. A respiration system for minimizing inspiration breathing gas oxygen partial pressure FiO₂ while maintaining a desired arterial oxygen partial pressure PaO₂ for a patient, including a respirator which supplies breathing gas to the patient at a plurality of respirator parameters, comprising:

PaO₂ sensor means for sensing actual arterial oxygen partial pressure of a patient and supplying a signal corresponding thereto;

mixing means for mixing oxygen plus at least one other gas to supply a breathing gas mixture having an actual oxygen partial pressure FiO₂, value to the respirator,

regulator means connected to said mixer for regulating the relative amounts of oxygen and the other gas in the breathing gas, said regulator means having a nominal PaO₂ value and receiving the PaO₂ sensor means signal for regulating the mixing means so that the actual PaO₂ value approaches the PaO₂ value;

comparator means connected to the mixing means and having a lower threshold value Su;

storage means connected to said mixing means and said comparator means for storing said actual FiO₂ value and supplying that value as the So value to said comparator means for a subsequent comparison step of said comparator means, said comparator means comparing said actual FiO₂ value from said mixing means with said Su and So values;

clocking means associated with said comparator means for establishing a time period as the duration of each comparison step;

parameter adjustment means connected to the respirator and the comparator means for selectively adjusting said plurality of respirator parameters, one at a time, in a selected direction and by a selected increment; and

control means operatively connected to said comparator means and said storage means for controlling the parameter adjustment means to select one of said plurality of respiratory parameters and adjust said one selected respiratory parameter in accordance with one of the following conditions;

(i) with the actual FiO₂ value being between the Su and So values during a comparison step duration, the control means being operable to cause the parameter adjustment means to make an adjustment of said one parameter in a positive or negative direction, store the direction of said adjustment, and select another of said plurality of respiratory parameters for adjustment;

(ii) with the actual FiO₂ value being outside the range between the Su and So values, said control means being operable to maintain the So value of the previous comparison step in said storage means, reverse the direction of adjustment of the previous selected parameter and adjust the previous selected parameter by a selected increment in the reverse direction, and adjust the one selected parameter in a position or negative direction.

2. A respirator system according to claim 1, wherein said control means comprises a microprocessor for storing the direction of the adjustment of said parameter adjustment means.

3. A respirator system according to claim 2, including a plurality of additional sensor means for sensing additional conditions of the patient, a window comparator connected to each of said additional sensor means for producing a signal when a respective one of the conditions rises above and falls below selected values therefor, said former mentioned comparator means producing no signal when said actual FiO₂ value is between said So and Su values and for producing a signal when said actual FiO₂ value is outside the range between said So and Su values, an OR-gate having a plurality of inputs connected to each of said window comparators and said formerly mentioned comparator means and an output connected to said microprocessor, said microprocessor being operable to make adjustments in said respirator parameters through said parameter adjustment means with no signal coming from said OR-gate and, to cancel adjustment of one of of the respirator parameters and to change the direction of adjustment of said one of said respirator parameters with a signal coming from said OR-gate.

4. A respiration system according to claim 3 including a warning device connected to each of said window comparators.

5. A respiration system according to claim 3 including a warning device connected to said comparator means indicating when said comparator means continues to produce a signal even after said control means has changed the direction of said adjustment.

6. A respirator system according to claim 3 including an alarm connected to said control means.

7. A method of minimizing inspiration breathing gas oxygen partial pressure FiO₂ while maintaining a desired arterial oxygen partial pressure PaO₂ for a patient using a respirator which supplies breathing gas to the patient having a plurality of respirator parameters, comprising:

(a) sensing the actual PaO₂ value of the patient;

(b) providing a nominal PaO₂ value for the patient;

(c) supplying the actual and nominal PaO₂ values to a regulator which is connected to a gas mixer, for controlling the gas mixer to adjust an amount of oxygen provided in breathing gas for the mixer to the patient so that the actual PaO₂ value can be made to approach the nominal PaO₂ value, the breathing gas having an actual oxygen partial pressure value FiO₂ ;

(d) comparing the actual FiO₂ value with upper and lower threshold values for the FiO₂ value, So and Su, respectively;

(e) storing the actual FiO₂ value to act as the So value in a following comparison step;

(f) automatically selecting a parameter of the plurality of parameters and modifying said parameter in accordance with one of the following conditions;

(i) with the actual FiO₂ value being between the stored So and the Su values, adjusting the selected parameter of the plurality of respirator parameters by a selected increment in a positive or negative direction, storing the direction of the adjustment, and repeating steps (a) to (f) for each respirator parameter;

(ii) with the actual FiO₂ value being out of the range between So and Su, maintaining the So value of a previous comparison step, reversing the stored direction of the adjustment of the previous selected respirator parameter and adjusting the previous selected parameter by a selected increment in the reverse direction, and repeating steps (a) to (f) for the selected respirator parameter.