Liquid antiseptic cleaners with improved foaming properties

• US 4,326,977 A
• Filed: 11/10/1980
• Issued: 04/27/1982
• Est. Priority Date: 11/10/1980
• Status: Expired due to Term

• Current Assignee: BASF Corporation (BASF SE)
• Original Assignee: BASF Wyandotte Corporation
• Inventors: Schmolka, Irving R.
• Primary Examiner(s): ALBRECHT, DENNIS
• Application Number:
  US06/205,115
• Time in Patent Office: 533 Days
• Field of Search: 252/106, 252/107, 252/174.21, 252/174.22, 252/351, 252/173, 424/326
• US Class Current: 510/132
• CPC Class Codes: A61K 8/43 Guanidines
• CPC Class Codes: A61K 8/90 Block copolymers A61K8/89 takes precedence
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations
• CPC Class Codes: C11D 3/3707 Polyethers, e.g. polyalkyleneoxides
• CPC Class Codes: C11D 3/48 Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
• CPC Class Codes: Y10S 516/01 Wetting, emulsifying, dispersing, or stabilizing agents

Abstract

A skin cleansing composition comprising an antiseptic agent, a polyoxyethylene-polyoxybutylene block copolymer wherein the polyoxybutylene portion of the compound has a molecular weight of from 500 to 2000 and the polyoxyethylene portions contribute from about 60 to 90 percent by weight of the compound and water.

Claims

1. A skin cleansing composition having good foaming properties comprising an agent selected from the group consisting of parachloro meta xylenol, hexachlorophene, 2-bromo-2-nitropropane diol, salicylanilide, didecyl dimethyl ammonium chloride, cetyl dimethylethyl ammonium bromide, alkyl dimethyl benzyl ammonium chloride, alkyl dimethylethyl benzyl ammonium chloride, alkyl dimethylbenzyl ammonium succinate, alkyl dimethyl-3,4-dichlorobenzyl ammonium chloride, 3,3'"'"',4'"'"',5-tetrachlorosalicylanilide, 3'"'"',4'"'"',5-trichlorosalicylanilide, 3,5-dibromo-3'"'"'-trifluoromethylsalicylanilide, 3,4,4'"'"'-trichlorocarbamilide, benzalkonium chloride, chloramine, iodine, iodophors, chlorhexidine and salts thereof, in normal antiseptic amounts agent, a polyoxyethylene-polyoxybutylene block copolymer wherein the polyoxybutylene portion of the compound has a molecular weight of from 500 to 2000 and the polyoxyethylene portions contribute from about 60 to 90 percent by weight of the compound in an amount of from 5 to 40 percent w/v and the balance substantially water.

2. The composition of claim 1 wherein said polyoxyethylene-polyoxybutylene block copolymer has the formula:

Ps

space="preserve" listing-type="equation">HO(C.sub.2 H.sub.3 O).sub.a (C.sub.4 H.sub.8 O).sub.b (C.sub.2 H.sub.4 O).sub.c H

wherein a, b and c are integers such that the copolymer consists of 60 to 90 percent by weight polyoxyethylene groups and wherein the molecular weight of the polyoxybutylene groups is about 500 to 2000.

3. The composition of claim 2 wherein said antiseptic is a chlorhexidine compound.

4. The composition of claim 2 wherein said cleansing composition is a concentrate consisting essentially of about 0.5 to 10 percent w/v of antiseptic agent, 5 to 40 percent w/v said block copolymer, and 95 to 50 percent by weight water.

5. The composition of claim 4 wherein said antiseptic agent is a chlorhexidine compound.

6. The composition of claim 5 wherein said chlorhexidine compound is a salt of chlorhexidine selected from the group consisting of the gluconate, isethionate, formate, acetate, glutamate, succinamate, mono-diglycolate, di-methanesulfonate, lactate, diisobutyrate and glucoheptanate salt.

7. The composition of claim 6 wherein said chlorhexidine compound is chlorhexidine gluconate.

8. The composition of claim 4 wherein said composition includes conventional additives selected from perfumes, coloring agents and preservatives, isopropyl alcohol, ethyl alcohol, methyl p-hydroxybenzoate or propyl p-hydroxybenzoate, and pH adjusting agents and mixtures thereof.

9. The skin cleaning composition of claim 2 which consists essentially of about 5×

10^-5 to 1.0 percent w/v of the antiseptic agent, 5×

10^-4 to 4.0 percent w/v of said block copolymer, balance water.

10. The composition of claim 9 wherein said chlorhexidine compound is a salt of chlorhexidine selected from the group consisting of the gluconate, isethionate, formate, acetate, glutamate, succinimate, mono-diglycolate, di-methanesulfonate, lactate, diisobutyrate and glucoheptanate salt.

11. The composition of claim 10 wherein said chlorhexidine compound is chlorhexidine gluconate.

12. The composition of claim 9 wherein said composition includes conventional additives selected from perfumes, coloring agents and preservatives, isopropyl alcohol, ethyl alcohol, methyl p-hydroxybenzoate or propyl p-hydroxybenzoate, and pH adjusting agents and mixtures thereof.