Preparation of 2,3-dichloro-5-trichloromethylpyridine

• US 4,331,811 A
• Filed: 03/12/1981
• Issued: 05/25/1982
• Est. Priority Date: 03/12/1981
• Status: Expired due to Fees

• Current Assignee: The Dow Chemical Company (Dow, Inc.)
• Original Assignee: The Dow Chemical Company (Dow, Inc.)
• Inventors: Werner, John A., Wilson, Charles A., Mixan, Craig E.
• Primary Examiner(s): Rotman, Alan L.
• Application Number:
  US06/243,166
• Time in Patent Office: 439 Days
• Field of Search: 546/345, 546/346
• US Class Current: 546/345
• CPC Class Codes: B01J 2231/4277 C-X Cross-coupling, e.g. nucleophilic aromatic amination, alkoxylation or analogues
• CPC Class Codes: B01J 2531/64 Molybdenum
• CPC Class Codes: B01J 2531/66 Tungsten
• CPC Class Codes: B01J 2531/821 Ruthenium
• CPC Class Codes: B01J 31/20 Carbonyls
• CPC Class Codes: C07D 213/26 Radicals substituted by halogen atoms or nitro radicals

Abstract

Preparation of 2,3-dichloro-5-trichloromethylpyridine in high yields and purity by chlorinating 2-chloro-5-trichloromethylpyridine at 70° to 250° C. with chlorine in the presence of a catalyst containing one or more molybdenum, tungsten or ruthenium compounds.

Claims

1. In a process for making 2,3-dichloro-5-trichloromethylpyridine by contacting 2-chloro-5-trichloromethylpyridine with chlorine in the presence of a catalyst at a temperature of 70°

to 250°

C., the improvement comprising employing a catalyst selected from the group consisting of tungsten hexacarbonyl or molybdenum hexacarbonyl.

2. Process of claim 1 wherein the temperature is from 150°

to 200°

C.

3. Process of claim 1 wherein the reaction is carried out under ambient pressure conditions.

4. Process of claim 1 wherein the reaction is carried out under elevated pressure conditions.