Imaging systems

• US 4,333,053 A
• Filed: 02/28/1980
• Issued: 06/01/1982
• Est. Priority Date: 03/13/1979
• Status: Expired due to Term

• Current Assignee: Picker International, Inc. (Marconi Holdings Company Limited)
• Original Assignee: EMI (Entegris Incorporated)
• Inventors: Burl, Michael, Harrison, Colin G.
• Primary Examiner(s): Tokar, Michael J.
• Application Number:
  US06/125,495
• Time in Patent Office: 824 Days
• Field of Search: 324/300, 324/307, 324/309
• US Class Current: 324/307
• CPC Class Codes: G01R 33/3621 NMR receivers or demodulators, e.g. preamplifiers, means for frequency modulation of the MR signal using a digital down converter, means for analog to digital conversion [ADC] or for filtering or processing of the MR signal such as bandpass filtering, resampling, decimation or interpolation

Abstract

In known NMR imaging apparatuses it has been the practice to arrange the G_R field gradient, which rotates in the plane of the examined slice, with a zero crossing substantially in the center of the slice and to demodulate at the Larmor frequency at the zero crossing. It is now proposed to demodulate the detected resonance signals at a frequency which, in the presence of the field gradient, is for a part of the plane lying outside the body slice. This may be by arranging the zero-crossing to be outside the slice. In that case it is preferable that the zero-crossing of G_R lies on a straight line (27) maintained tangential to a circle (28) lying outside the body (23) about an axis (24) through the slice. Control may then be by precalculated coil currents or by precalculating fields at probe positions and adjusting the coil currents to give the expected fields.

Alternatively the zero-crossing may be maintained at the center and demodulation may be at a different frequency. It is then desirable also to measure the resonance frequency in the absence of the field gradient across the slice. The resonance signals are then effectively further demodulated at that measured frequency. The effective demodulation is preferably achieved by complex multiplication of the two signals.

Claims

1. A nuclear magnetic resonance apparatus, for examining a substantially planar slice of a body, the apparatus including means for applying magnetic fields to cause resonance preferentially in the plane of said slice, means for applying a pulsed magnetic field having a gradient across the plane of the slice to produce phase dispersion in said resonance, means for sensing resonance signals induced during said pulsed field for a plurality of different directions thereof, means for demodulating the resonance signals and means for further processing the demodulated signals to provide a representation of said slice, wherein the resonance signals are demodulated at a frequency which, in the presence of the said magnetic fields and pulsed magnetic field, is the resonance frequency for a position in the plane lying outside said slice.

2. An apparatus according to claim 1 in which the means for applying the pulsed field is arranged so that said field has a gradient with a zero crossing at the centre of the slice and the means for demodulating is arranged to demodulate at a frequency which is the resonance frequency for a position in the plane lying outside said slice in the presence of said gradient.

3. An apparatus according to claim 2 including means for effectively further demodulating the first demodulated signals to provide signals representing the change of frequency produced by the gradient.

4. An apparatus according to claim 3 including means for repeating the sensing of the resonance signals in the presence of the magnetic fields but not the pulsed gradient field and means for effectively demodulating said first sensed resonance signals at the frequency of said second sensed resonance signals.

5. An apparatus according to claim 4 in which the first and second sensed resonance signals are multiplied in complex manner to achieve said effective demodulation.

6. An apparatus according to claim 1 in which the pulsed field has a zero crossing in the plane lying outside said slice and the demodulation frequency is the resonance frequency for the plane in the absence of said pulsed field.

7. A nuclear magnetic resonance apparatus, for examining a substantially planar slice of a body, the apparatus including means for applying magnetic fields to cause resonance preferentially in the plane of said slice, means for applying a pulsed magnetic field having a gradient across the plane of the slice to produce phase dispersion in said resonance and repeating the pulsed magnetic field for a plurality of different directions of said gradient in sequence, and means for sensing a resonance signal induced during said pulsed field for each of said directions thereof wherein the means for applying the pulsed field is arranged so that said pulsed field is only of one polarity within said slice.

9. An apparatus according to either claim 7 or claim 8 in which the means for applying the pulsed magnetic field include two coil arrangements disposed to provide component fields having orthogonal gradients and control means arranged to control the proportions of said component fields to vary the direction of said first-mentioned gradient and wherein each coil arrangement is split into opposing parts and the control means are also arranged to control the proportion of each field provided by the respective parts to vary the position of the zero value of the respective component fields.

10. An apparatus according to claim 9 in which the control means are adapted to produce predetermined currents in each coil part in sequence.

8. A nuclear magnetic resonance apparatus, for examining a substantially planar slice of a body, the apparatus including means for applying magnetic fields to cause resonance preferentially in the plane of said slice, means for applying a pulsed magnetic field having a gradient across the plane of the slice in each of a plurality of different directions at different times, to produce phase dispersion in said resonance, and means for sensing a resonance signal induced during said pulsed field for each of said plurality of different directions thereof, wherein the means for applying the pulsed field is arranged so that the pulse field has a zero value along a straight line which is in the place of said slice and which, for said different directions of said gradient, is tangential to a circle surrounding the body.

11. A nuclear magnetic resonance apparatus for examining a substantially planar slice of a body, the apparatus including means for applying magnetic fields to cause resonance preferentially in the plane of said slice, means for applying a pulsed magnetic field having a gradient across the plane of the slice to produce phase dispersion in said resonance and repeating the pulsed magnetic field for a plurality of different directions of said gradient at different times, the means for applying the pulsed field being arranged so that the pulsed field is only of one polarity within the slice, means for sensing a resonance signal induced during said pulsed field for each of said directions, probe means to measure the magnetic fields at different positions in the region of the slice and means for determining the differences between the measured fields and for controlling the means for applying the pulsed magnetic field to reduce said differences.

12. An apparatus according to claim 11 in which correcting currents in coils producing the magnetic fields are provided by multiplying the field differences by an inverted matrix of fields produced by unit current in each of said coils.

13. A method of examining a substantially planar slice of a body by nuclear magnetic resonance, the method including:

applying magnetic fields to cause resonance preferentially in the plane of the slice;

applying a pulsed magnetic field having a gradient across the plane of the slice to produce phase dispersion in said resonance;

sensing the resonance signals induced during said pulsed field for a plurality of different directions thereof;

demodulating the resonance signals and further processing the demodulated signals to provide a representation of said slice;

wherein the resonance signals are demodulated at a frequency which, in the presence of the said magnetic fields and pulsed magnetic field, is the resonance frequency for a position in the plane lying outside said slice.

14. A method according to claim 13 in which the pulsed field has a gradient with a zero crossing at the centre of the slice and the demodulation frequency is the resonance frequency for a position in the plane lying outside said slice in the presence of said gradient.

15. A method according to claim 14 in which the first demodulated signals are further demodulated to provide signals representing the change of frequency produced by the gradient.

16. A method according to claim 15 including repeating the sensing of the resonance signals, in the presence of the magnetic fields but not the pulsed gradient field, and effectively demodulating said first obtained resonance signals at the frequency of said second sensed resonance signals.

17. A method according to claim 16 in which the first and second sensed resonance signals are multiplied in complex manner to achieve said effective demodulation.

18. A method according to claim 13 in which the pulsed field has a zero crossing in the plane but lying outside said slice and the demodulation frequency is the resonance frequency for the plane in the absence of said pulsed field.

19. A method according to claim 18 in which, for said plurality of directions of said gradient, the zero-crossing of said gradient is arranged to be along a straight line, in the plane of the slice, tangential to a circle surrounding the body.

20. A method of examining a substantially planar slice of a body by nuclear magnetic resonance, the method including applying magnetic fields to cause resonance preferentially in the plane of the slice, applying a pulsed magnetic field having a gradient across the plane of the slice to cause phase dispersion in said resonance, sensing the resonance signals produced thereby and repeating the procedure for a plurality of different directions of said gradient in sequence, wherein the pulsed field is arranged to have a zero value which lies in said plane but outside said slice.

22. A method according to either claim 20 or claim 21 in which the currents in coils producing said pulsed field are predetermined and are applied in a predetermined sequence.

23. A method according to either claim 20 or 21 in which the field values at a plurality of points in the region of the body are predetermined for the different directions of said gradient, the actual fields achieved at those points are measured and the means for producing the fields are adjusted to reduce differences between the predetermined and measured fields.

21. A method of examining a substantially planar slice of a body by nuclear magnetic resonance, the method including applying magnetic fields to cause resonance preferentially in the plane of the slice, applying a pulsed magnetic field, having a gradient across the plane of said slice and a zero value which is in said plane but outside said slice, to cause phase dispersion in said resonance, sensing the resonance signals, produced thereby and repeating the procedure for each of a plurality of different directions of said gradient, wherein the zero-value of said pulsed field is arranged to be along a straight line which is in the plane of the slice and which, for said different directions of said gradient, is tangential to a circle surrounding the body.

24. A method of examining a substantially planar slice of a body by nuclear magnetic resonance, the method including:

applying magnetic fields to cause resonance preferentially in the plane of the slice;

applying a pulsed magnetic field having a gradient across the plane of the slice with a zero crossing within the slice to produce phase dispersion in said resonance;

sensing the resonance signals induced during said pulsed field;

demodulating the resonance signals at a frequency which, in the presence of said magnetic fields and pulsed magnetic field, is the resonance frequency for a position in the plane lying outside said slice;

repeating the sensing of the resonance signals in the presence of the first mentioned magnetic fields but not the pulsed gradient field;

effectively demodulating said first obtained resonance signals at the frequency of said second sensed signals;

repeating the preceding steps for a plurality of different directions of said gradient and further processing the demodulated signal for said different directions to provide a representation of said slice.