Method and apparatus for detecting and/or imaging clusters of small scattering centers in the body

• US 4,338,948 A
• Filed: 03/27/1980
• Issued: 07/13/1982
• Est. Priority Date: 03/27/1980
• Status: Expired due to Term

• Current Assignee: Regents of the University of California (University of California)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Perez-Mendez, Victor, Sommer, Frank G.
• Primary Examiner(s): Pellegrino, Stephen C.
• Assistant Examiner(s): Jaworski, Francis J.
• Application Number:
  US06/134,624
• Time in Patent Office: 838 Days
• Field of Search: 128/660-661, 73/597-598, 73/602, 73/609-612, 73/614, 73/618-626
• US Class Current: 600/437
• CPC Class Codes: A61B 8/0825 for diagnosis of the breast, e.g. mammography
• CPC Class Codes: Y10S 128/915 Ultrasound mammography

Abstract

An ultrasonic method and apparatus are provided for detecting and imaging clusters of small scattering centers in the breast wherein periodic pulses are applied to an ultrasound emitting transducer and projected into the body, thereafter being received by at least one receiving transducer positioned to receive scattering from the scattering center clusters. The signals are processed to provide an image showing cluster extent and location.

Claims

1. An apparatus for detecting clusters of scattering centers in a volume of a body, comprising:

means for directing ultrasonic energy towards a given cluster of scattering centers in periodic bursts of ultrasonic energy at a predetermined frequency;

means for receiving some of said directed ultrasonic energy at a plurality of different points circumferentially spaced around said body after said energy has come in contact with said cluster of scattering centers, said receiving means distinguishing between received ultrasonic energy having substantially the same, common amplitude at the various receiving points from received ultrasonic energy having differing amplitudes at the various receiving points, whereby to distinguish scattered ultrasonic energy having substantially the same amplitude at all of the receiving points from noise or reflected ultrasonic energy; and

means responding only to the scattered ultrasonic energy received and distinguished by said receiving means for producing a corresponding output signal.

2. Apparatus as in claim 1 where the predetermined frequency has a wavelength of the same order of magnitude as the size of the scattering centers.

3. Apparatus as in claim 1 together with means for receiving and processing said output signal and for receiving the processed signal and displaying an image of the clusters.

4. Apparatus as in claim 1 wherein said receiving means includes a plurality of receiving transducers disposed at different positions in a plane and directed to receive the scattered ultrasound energy for providing said output signal.

5. Apparatus as in claim 4 including means for receiving and processing said output signal to provide an image of the clusters and their location.

6. Apparatus as in claim 1 wherein said means for processing said signal and providing an indication of said clusters indicates the size and location of said clusters.

7. An apparatus according to claim 1 wherein said receiving points are located at selected angles around said body between 20°

and 170°

with respect to said directing means.

8. An apparatus according to claim 1 wherein said ultrasonic energy directing means is positioned at a fixed location relative to said body and wherein said receiving means includes separate receivers at selected angles around said body between 20°

and 170°

with respect to said ultrasonic energy directing means.

9. An apparatus for detecting clusters of scattering centers in a volume of a body comprising:

a steerable transmitting transducer for receiving electrical high frequency pulses and emitting pulses of ultrasonic energy at a predetermined frequency into said body in response to the pulses;

means including a plurality of spaced receiving transducers positioned around said body to receive said ultrasonic energy after the latter has come in contact with said clusters of scattering centers and circuitry for distinguishing between received energy having substantially the same, common amplitude at the various transducers from energy of varying amplitude at the various transducers and for generating electrical signals corresponding to the ultrasonic energy having said common amplitude, whereby said generated signals correspond to scattered ultrasonic energy as opposed to noise or reflected ultrasonic energy; and

means for receiving and processing said signals to provide indications of said clusters.

10. A method of detecting clusters of scattering centers in a volume of material, comprising:

directing ultrasonic energy towards a given cluster of scattering centers in periodic bursts of ultrasonic energy at a predetermined frequency;

receiving some of said directed ultrasonic energy at a plurality of different points circumferentially spaced around said body after said energy has come in contact with said cluster of scattering centers;

distinguishing between received ultrasonic energy having substantially the same, common amplitude at the various receiving points from received ultrasonic energy having differing amplitudes at various receiving points, whereby to distinguish scattered ultrasonic energy having substantially the same amplitude at all of the receiving points from noise or reflected ultrasonic energy; and

responding only to the scattered ultrasonic energy received and distinguished for producing a corresponding output signal.