Molded body comprising vegetable oil for generating aerosol for treating athlete's foot

• US 4,340,053 A
• Filed: 10/22/1980
• Issued: 07/20/1982
• Est. Priority Date: 06/20/1980
• Status: Expired due to Term

• Current Assignee: Kiichiro Sarui
• Original Assignee: Kiichiro Sarui
• Inventors: Sarui, Kiichiro
• Primary Examiner(s): Cannon, James C.
• Application Number:
  US06/199,544
• Time in Patent Office: 636 Days
• Field of Search: 424/27, 424/28, 424/38, 424/358, 424/40, 36/43, 428/256, 422/305, 219/271, 219/274, 128/256, 128/260, 128/368, 128/383
• US Class Current: 604/293
• CPC Class Codes: A61F 2007/0028 Rectum
• CPC Class Codes: A61F 2007/0045 Foot
• CPC Class Codes: A61F 7/03 thermophore, i.e. self-heating, e.g. using a chemical reaction
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 36/47 Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• CPC Class Codes: A61K 36/55 Linaceae (Flax family), e.g. Linum
• CPC Class Codes: A61K 36/63 Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
• CPC Class Codes: A61K 36/8962 Allium, e.g. garden onion, leek, garlic or chives
• CPC Class Codes: A61K 41/13 by ultrasonic waves
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: Y10T 442/109 Metal or metal-coated fiber-containing scrim

Abstract

A molded body for generating an aerosol for treating athlete'"'"'s foot comprised of a vegetable oil composition which is solid at room temperature. The composition may additionally contain a metal catalyst for accelerating the oxidation of the vegetable oil or an organic catalyst for retarding the progress of the oxidation of the vegetable oil. The molded body becomes molten on being heated and then generates an aerosol which treats athlete'"'"'s foot. Being solid at ordinary temperatures, this aerosol generating body is easy to handle and safe for use in an athlete'"'"'s foot treating apparatus.

Claims

1. A method for treating athlete'"'"'s foot fungal infection which comprises contacting a portion of the skin afflicted with such fungus with an aerosol produced by heating a molded body comprising a vegetable oil containing composition which is solid at room temperature and which melts upon heating to generate said aerosol, said aerosol comprising an effective amount of oxidation products of such vegetable oil to destroy said fungus.

2. The method according to claim 1 wherein said fungus is of the genus Trichophyton.

3. The method according to claim 1 wherein said molded body comprises said vegetable oil composition deposited on a wire mesh substrate.

4. The method according to claim 1 wherein said oxidation products comprise hydroperoxides.

5. The method according to claim 4 wherein said composition is heated to 40°

C. to 80°

C.

6. The method according to claim 5 wherein said composition contains a metal oxidation catalyst and organic oxidation inhibitor or both.

7. A molded body for treating athlete'"'"'s foot comprising a vegetable oil containing composition which is solid at room temperature and which melts upon heating to form an aerosol containing an effective amount of oxidized products of said vegetable oil to treat athlete'"'"'s foot.

8. The molded body according to claim 7 wherein said vegetable oil has the following physical properties:

space="preserve" listing-type="tabular">______________________________________ Specific gravity 15°

/15°

0.911-0.943 Refractive index 1.468/15°

-1.478/15°

Saponification value 186-215 Iodine value 83-180 Acid value 1-20 Unsaponifiable matter 0.2-3% Melting point (mixed fatty acids) 13-70°

C. ______________________________________

9. The molded body according to claim 7 wherein said composition further contains a metal oxidation catalyst and organic oxidation inhibitor or both.

10. The molded body according to claim 7 wherein said vegetable oil is deposited on a wire mesh substrate.