Novel material for immunological assay of biochemical components and a process for the determination of said components
First Claim
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1. A microcapsule comprising an oily liquid core material and a wall material having bound thereto an antigen or antibody to the surface thereof, wherein a marking substance is incorporated into said core material.
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Abstract
Antigen- or antibody-bound microcapsules are employed for immunological assay of biochemical components having immunological activity. The microcapsule system provides high detection sensitivity, high accuracy and excellent reproducibility in immunological assay, without causing non-specific reaction. The microcapsules can be labelled with isotopes, enzymes, etc., for use in quantitative assays of trace amounts of biochemical components.
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37 Claims
- 1. A microcapsule comprising an oily liquid core material and a wall material having bound thereto an antigen or antibody to the surface thereof, wherein a marking substance is incorporated into said core material.
- 10. A method for determining a biological component having immunological activity which comprises mixing a microcapsule comprising an oily liquid core material and a wall material having bound thereto an antigen or antibody at the surface thereof with said biological component to thereby cause an immunological reaction therebetween, wherein a marking substance is incorporated into said core material.
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