Sustained release pharmaceutical composition of solid medical material
First Claim
1. A sustained release pharmaceutical composition comprising a coronary and cerebral vascular dilating-effective amount of an amorphous form of nicardipine or a salt thereof, and polyethylene oxide in the form of a fine powder or fine particle granules.
0 Assignments
0 Petitions
Accused Products
Abstract
Sustained release pharmaceutical composition of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl pyrrolidone, carboxyvinyl polymer, hydroxypropylmethyl cellulose phthalate, cellulose acetate phthalate, methyl meta-acrylate meta-acrylic acid copolymer, polyvinylacetal diethylaminoacetate, dimethylaminoethyl meta-acrylate meta-acrylic acid copolymer, 2-methyl-5-vinylpyridinemethyl acrylate meta-acrylic acid copolymer, citric acid, urea, succinic acid and amino acid, and may further contain one basic substance selected from the group consisting of a surface active agent, polyethylene glycol, propylene glycol, glycerin, a glycerin fatty acid ester and a vegetable oil (first embodiment): and in the case where the solid medical material is nicardipine, the composition may consist only of the amorphous nicardipine or a salt thereof without the above compound (second embodiment).
-
Citations
13 Claims
- 1. A sustained release pharmaceutical composition comprising a coronary and cerebral vascular dilating-effective amount of an amorphous form of nicardipine or a salt thereof, and polyethylene oxide in the form of a fine powder or fine particle granules.
Specification