Dental caries detection

• US 4,347,233 A
• Filed: 11/29/1979
• Issued: 08/31/1982
• Est. Priority Date: 12/04/1978
• Status: Expired due to Term

• Current Assignee: Kuraray Company Limited
• Original Assignee: Kuraray Company Limited
• Inventors: Omura, Ikuo, Yamauchi, Junichi, Shibatani, Kyoichiro, Nagase, Yoshinori, Ikeguchi, Eiji
• Primary Examiner(s): Fagelson, Anna P.
• Application Number:
  US06/098,686
• Time in Patent Office: 1,006 Days
• Field of Search: 424/7, 424/9, 424/49
• US Class Current: 424/9.7
• CPC Class Codes: A61K 2800/43 Pigments; Dyes
• CPC Class Codes: A61K 49/006 Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
• CPC Class Codes: A61K 8/466 containing sulfonic acid derivatives; Salts
• CPC Class Codes: A61K 8/498 having 6-membered rings or their condensed derivatives, e.g. coumarin
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

A caries detector, comprising a solution of a dye selected from the group consisting of Phloxine B (CI 45410), Phloxine BK (the corresponding dipotassium salt of CI 45410), Acid Red (CI 45100), Fast Acid Magenta (CI 17200), Fast Green FCF (CI 42053) and Rhodamine B (CI 45170) in a solvent.

Claims

1. A method for distinguishing, by observation with visible light, between the carious portion and the sound portion of a decaying tooth by selectively dyeing the carious portion, which comprises applying a solution of Acid Red (CI 45100) in a concentration of from 0.1 to 5.0% by weight in a solvent which comprises at least 60% by weight of a mono-, di- or tri-hydroxy compound containing 2 to 20 carbon atoms to a decayed tooth to selectively dye the carious portion of the tooth, and then within 10 seconds after applying the solution washing away the remaining solution before the sound portion of the tooth is dyed with said solution.

2. The method of claim 1, wherein said solvent comprises at least 80% by weight of the mono-, di- or tri-hydroxy compound containing 2 to 10 carbon atoms.

3. The method of claim 2, wherein said solvent is triethylene glycol or propylene glycol.