Anion sensing electrode

• US 4,349,426 A
• Filed: 10/24/1980
• Issued: 09/14/1982
• Est. Priority Date: 10/26/1979
• Status: Expired due to Term

• Current Assignee: Hitachi, Ltd.
• Original Assignee: Hitachi, Ltd.
• Inventors: Mori, Junji, Sugahara, Kenshi
• Primary Examiner(s): Tung, T.
• Application Number:
  US06/200,458
• Time in Patent Office: 690 Days
• Field of Search: 204/1 T, 204/195 P, 204/195 M, 204/195 L, 204/1 B, 23/230 B
• US Class Current: 204/415
• CPC Class Codes: G01N 27/3335 the membrane containing at least one organic component G01N27/3271 takes precedence; aspects concerning the enzyme reagent in enzyme electrodes C12Q1/001

Abstract

A sensing membrane is fixed to one end of a tube comprising polyvinyl chloride. An aqueous sodium chloride solution is contained in the tube, and is in contact with an internal electrode wire. The sensing membrane comprises a support substance of polyvinyl chloride, a sensing substance of quaternary ammonium salt having an alkyl chain having 8 to 16 carbon atoms, and a plasticizer of normal decyl alcohol. Anions in a body fluid sample can be measured with a small measurement error by an electrode provided with the sensing membrane of that composition.

Claims

1. An anion sensing electrode which comprises a vessel means containing an inner filling solution;

an internal electrode in contact with the inner filling solution;

a sensing membrane fixed to the vessel means, said sensing membrane containing a polymeric substance as a support substance, a quaternary ammonium salt as a sensing substance and normal tetradecyl alcohol as a plasticizer.

2. An anion sensing electrode according to claim 1, wherein the sensing membrane comprises 10-20% by weight of the sensing substance, 20-40% by weight of the alcohol and 40-60% by weight of the support substance, making total 100% by weight.

3. An anion sensing electrode according to claim 1 or 2, wherein the quaternary ammonium salt is an aliphatic ammonium salt having alkyl groups of 8 to 16 carbon atoms.

4. An anion sensing electrode according to claim 1 or 2, wherein the support substance is selected from polyvinyl chloride, polycarbonate, and silicone rubber.

8. An anion sensing electrode according to claim 1 or claim 5, wherein the quaternary ammonium salt is selected from the group consisting of methyl-n-tridodecyl ammonium chloride, methyl-n-tetradecyl ammonium chloride, and methyl-n-trioctyl ammonium chloride and the support substance is polyvinyl chloride.

9. An anion sensing electrode according to claim 1 or claim 8, wherein said sensing membrane comprises an admixture of the support substance, the sensing substance and the plasticizer in the form of a sheet.

11. An anion sensing electrode according to claim 3, wherein the support substance is selected from polyvinyl chloride, polycarbonate, and silicone rubber.

5. An anion sensing electrode, which comprises a vessel means containing an inner filling solution;

an internal electrode in contact with the inner filling solution; and

a sensing membrane fixed to the vessel means, the sensing membrane comprising a polymeric substance as a support substance, a quaternary ammonium salt as a sensing substance and normal tetradecyl alcohol as a plasticizer;

the content of the support substance being not more than 60% by weight and the content of the plasticizer being more than the content of the sensing substance.

6. An anion sensing electrode according to claim 5, wherein the vessel means is a cylinder comprising polyvinyl chloride.

7. An anion sensing electrode according to claim 6 or 5, wherein the sensing membrane comprises 55% by weight of the support substance, 15% by weight of the sensing substance, and 30% by weight of the plasticizer.

10. An anion sensing electrode according to claim 5, wherein the sensing membrane comprises 40 to 60% by weight of the support substance and the ratio of the plasticizer to the sensing substance is at least 1.5.